Fengzeng Jian

ORCID: 0000-0001-7860-278X
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Spinal Dysraphism and Malformations
  • Cervical and Thoracic Myelopathy
  • Medical Imaging and Analysis
  • Cerebrospinal fluid and hydrocephalus
  • Spinal Cord Injury Research
  • Scoliosis diagnosis and treatment
  • Pelvic and Acetabular Injuries
  • Head and Neck Surgical Oncology
  • Musculoskeletal pain and rehabilitation
  • Spinal Hematomas and Complications
  • Intracranial Aneurysms: Treatment and Complications
  • Glioma Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Management of metastatic bone disease
  • Neurofibromatosis and Schwannoma Cases
  • Bone Tumor Diagnosis and Treatments
  • Congenital Anomalies and Fetal Surgery
  • Sarcoma Diagnosis and Treatment
  • Congenital Diaphragmatic Hernia Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Neuroblastoma Research and Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Nerve Injury and Rehabilitation

Capital Medical University
2016-2025

Chinese Institute for Brain Research
2020-2025

First Affiliated Hospital of Hebei Medical University
2025

Hebei Medical University
2025

Central Hospital of Zibo
2019-2024

Binzhou Medical University
2024

Beijing Tian Tan Hospital
2023

Beijing Xuanwu Traditional Chinese Medicine Hospital
2020-2022

Xuan Wu Hospital of the Capital Medical University
2021

First Affiliated Hospital Zhejiang University
2019

To report the surgical technique and clinical results for treatment of basilar invagination (BI) with atlantoaxial dislocation (AAD) by direct posterior reduction fixation using intraoperative distraction between occiput C2 pedicle screws.From May 2004 to June 2008, 29 patients who had BI AAD were surgically treated in our department. Pre- postoperative dynamic cervical x-rays, computed tomographic scans, 3-dimensional reconstruction views performed assess degree dislocation. Ventral...

10.1227/01.neu.0000367632.45384.5a article EN Neurosurgery 2010-03-17

OBJECTIVE Current treatment options for posttraumatic syringomyelia (PTS) lack clear standardization and often result in common complications. This study aims to introduce a novel minimally invasive technique modified subarachnoid−subarachnoid (S−S) bypass procedure PTS. METHODS The included 20 consecutive patients with symptomatic PTS who underwent the S−S bypass. surgical of involved two-laminae fenestration based on preoperative MRI myelography results showing normal subarachnoid space...

10.3171/2024.10.spine24987 article EN Journal of Neurosurgery Spine 2025-02-01

Abstract Background Clinical diagnosis and therapy for the lumbar disc herniation requires accurate vertebra segmentation. The complex anatomical structure degenerative deformations of vertebrae makes its segmentation challenging. Methods An improved level set method, namely edge- region-based method (ERBLS), is proposed CT images By considering gradient information local region characteristics images, model can efficiently segment with intensity inhomogeneity blurry or discontinuous...

10.1186/1475-925x-12-48 article EN cc-by BioMedical Engineering OnLine 2013-05-28

Oblique lumbar interbody fusion (OLIF) is a minimally invasive technique performed through the antero-oblique trajectory to address wide range of pathologies. However, it can lead complications. We reviewed results OLIF and discussed effective methods avoid such complications.Seventy-nine consecutive patients who underwent between May 2016 July 2019 were retrospectively analyzed. They divided into three groups: stand-alone, posterior, lateral fixation, according whether they followed up with...

10.21037/atm-20-2159 article EN Annals of Translational Medicine 2021-01-01

ABSTRACT Background Iatrogenic cervical kyphosis (ICK) often requires complex anterior and posterior correction, which is associated with multiple complications. Consequently, there a need to investigate alternative treatment approaches that streamline the operative process markedly diminish postoperative This study, therefore, aimed evaluate feasibility efficacy of single‐stage controllable antedisplacement fusion (ACAF) in revision surgeries for ICK. Methods A retrospective review was...

10.1111/os.14366 article EN cc-by-nc-nd Orthopaedic Surgery 2025-01-21

Revision surgery for patients with persistent, recurrent, or progressive syringomyelia following foramen magnum decompression (FMD) Chiari malformation I-syringomyelia (CM-SM) is not uncommon and presents both strategic technical challenges. We conducted a retrospective study including all who underwent revision Cerebellar Tonsillectomy (CTL) CM-SM between 2003 2023. Additionally, we performed uni- multivariate analyses to identify possible factors contributing failed CTL outcomes....

10.1016/j.wneu.2025.123690 article EN cc-by World Neurosurgery 2025-02-18

Syringomyelia was a rare condition characterized by the formation of fluid-filled cysts (syrinx) within spinal cord, resulting in sensory and motor dysfunction. Currently, there no satisfactory treatment for syringomyelia. Ependymal cells were integral to water transport may represent promising therapeutic target. Induction syringomyelia occurred 8-week old female rats followed histological analyses at 3-, 7-, 14-, 30-, 60-, 180-, 365-days later. Scanning electron microscope (SEM)...

10.1186/s12987-025-00631-2 article EN cc-by-nc-nd Fluids and Barriers of the CNS 2025-02-24

BACKGROUND AND OBJECTIVES: The exact pathways of fluid outflow within the central canal (CC) spinal cord are not completely understood. best management approach for patients with post-traumatic syringomyelia that progresses to cranial end CC, also known as syringobulbia (PT-syringobulbia), is still a topic debate. This study aims introduce new surgical indication foramen magnum and Magendie dredging (FMDD) procedure in PT-syringobulbia prospectively assess its outcomes. METHODS: included 15...

10.1227/neu.0000000000003378 article EN Neurosurgery 2025-03-03

OBJECTIVE The objective of this study was to develop a vertebral artery (VA) classification system that improves risk assessment using 2D map the VA position at craniovertebral junction (CVJ), and outline surgical strategies for managing anomalous VAs during posterior atlantoaxial joint release, distraction, fusion technique in treatment basilar invagination (BI) instability (AAI). METHODS In retrospective study, 125 patients (mean age 44.1 years) with BI AAI who underwent surgery between...

10.3171/2024.12.spine24185 article EN Journal of Neurosurgery Spine 2025-03-01

<title>Abstract</title> <bold>Purpose</bold> Current surgical options for treating nontraumatic adhesive syringomyelia, particularly in patients with a history of previous spinal canal intervention (PSCAS), lack clear standardization and frequently lead to common complications such as recurrent adhesions, tube disconnections, neurological injuries related myelotomy, resulting the need multiple revision surgeries. This study aims introduce novel, minimally invasive technique modified...

10.21203/rs.3.rs-6290624/v1 preprint EN Research Square (Research Square) 2025-04-04

Although cerebrospinal fluid (CSF)-based liquid biopsy was proved to be practical in molecular analysis of intracranial gliomas, primary intramedullary astrocytoma rarely reported. Given the distinct genomic profiles between glioma and astrocytoma, whether feasibility CSF-based gliomas can replicated spinal cord needs investigated. The aim this pilot study is evaluate through sequencing CSF-derived circulating tumor DNA (ctDNA).Two grade IV diffuse midline 1 II, I were included....

10.14245/ns.2346210.105 article EN cc-by-nc Neurospine 2023-06-30

Abstract BACKGROUND The management of atlantoaxial dislocation (AAD) associated with basilar invagination (BI) is challenging, and traditional posterior-only approaches lack the ability to release anterior soft tissue resulting in unsatisfactory reduction. Furthermore, vertebral artery anomalies deformed anatomy increase surgical risks. OBJECTIVE To introduce a safe efficient technique reduce congenital AAD BI through single-stage approach. METHODS A total 65 patients concomitant who had...

10.1093/ons/opaa391 article EN Operative Neurosurgery 2020-12-29

The authors recently used a combination of minimally invasive oblique lumbar interbody fusion (OLIF) and lateral fixation for the treatment degenerative spine deformity. early results were promising. Radiographic clinical as well complications retrospectively assessed in current study.Eleven patients with deformity underwent combined OLIF instrumentation without real-time electromyography (EMG) monitoring. measurements including coronal Cobb angle, central sacral vertebral line (CSVL),...

10.1155/2019/5672162 article EN BioMed Research International 2019-01-08
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