A5023231005- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Lung Cancer Research Studies
- Immune Response and Inflammation
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cell Adhesion Molecules Research
- Pancreatic and Hepatic Oncology Research
- NF-κB Signaling Pathways
- Pediatric health and respiratory diseases
- Immune responses and vaccinations
- Pulmonary Hypertension Research and Treatments
- Proteoglycans and glycosaminoglycans research
- Biomedical Research and Pathophysiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Hemoglobin structure and function
- Cytokine Signaling Pathways and Interactions
- Metabolism, Diabetes, and Cancer
- HER2/EGFR in Cancer Research
- Human Health and Disease
- Diet and metabolism studies
- Psoriasis: Treatment and Pathogenesis
- Alcohol Consumption and Health Effects
- Barrier Structure and Function Studies
- Heme Oxygenase-1 and Carbon Monoxide
Hospital for Sick Children
2019-2022
Tohoku University
2012-2021
Baqiyatallah University of Medical Sciences
2010-2013
Tohoku University Hospital
2012
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital
2012
Payame Noor University
2010
Abstract Background Sulfur mustard (SM) is a blister-forming agent that has been used as chemical weapon. can cause damage in various organs, especially the skin, respiratory system, and eyes. Generally, multiple complications of gas result from its alkalizing potency; it reacts with cellular components like DNA, RNA, proteins, lipid membranes. TGF-β multi-functional cytokine biological effects ranging cell differentiation growth inhibition to extracellular matrix stimulation,...
Airway remodelling is characterized by the thickening and reorganization of airways seen in mustard lung patients. Mustard general description for chronic obstructive pulmonary disease induced sulfur mustard(SM). Pulmonary was diagnosed as most important disorder individuals that had been exposed to mustard. Sulfur a chemical warfare agent developed during Wars. Iraqi forces frequently used it against Iranian Iran -Iraq 1980-1988. Peribronchial fibrosis result from airway remodeling include...
Sulfur mustard (SM) is known as an effective chemical agent and was used in the 1980s during Iran-Iraq war against Iranians. At present time, there are more than 40,000 people suffering from pulmonary lesions due to gas Iran. Though much about gross pathology of SM damage, molecular cellular basis for this not well understood.One most important protein groups involved inflammatory responses nuclear factor κB (NF-κB1) family. They belong category DNA-binding factors necessary transcription...
<b><i>Background:</i></b> Pancreatic neuroendocrine tumors (PNETs) have been reported to express progesterone receptor (PR), and its expression has demonstrated be a favorable prognostic factor in these patients. We examined the status of PR isoforms PRA PRB human PNET cell line their association with proliferation tumor cells, which is closely related clinical outcome <b><i>Methods:</i></b> Quantitative RT-PCR assays were performed following...
Sulfur mustard (SM), is an alkylating agent and has been emerged as a chemical weapon in various battlefields. More recently, SM was employed the Iraq conflict against Iranian military forces civilians. Nowadays there are more than 40,000 people suffering from pulmonary lesions special chronic obstructive disease (COPD) due to gas Iran. causes endogenous production of reactive oxygen species (ROS).Heme oxygenases (HOs) rate-limiting enzyme for heme metabolism. Numerous studies have confirmed...
Endothelia determine blood-to-tissue solute delivery, yet glucose transit is poorly understood. To illuminate mechanisms, we tracked [3H]-2-deoxyglucose (2-DG) in human adipose-tissue microvascular endothelial cells. 2-DG uptake was largely facilitated by the transporters GLUT1 and GLUT3. Once cytosol, >80% of became phosphorylated ∼20% incorporated into glycogen, suggesting that transported readily accessible to cytosolic enzymes. Interestingly, a fraction intracellular released over time...