A5064914016- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Multiple Sclerosis Research Studies
- Advanced Neuroimaging Techniques and Applications
- Epilepsy research and treatment
- MRI in cancer diagnosis
- Biotin and Related Studies
- Social and Educational Sciences
- RNA regulation and disease
- Medical Imaging Techniques and Applications
- Neural dynamics and brain function
Karolinska Institutet
2015-2020
John Wiley & Sons (United States)
2020
Hudson Institute
2020
Karolinska University Hospital
2020
Lund University
2011
<h3>BACKGROUND AND PURPOSE:</h3> Quantitative MR imaging techniques are gaining interest as methods of reducing acquisition times while additionally providing robust measurements. This study aimed to implement a synthetic method on new scanner type and compare its diagnostic accuracy volumetry with conventional in patients MS controls. <h3>MATERIALS METHODS:</h3> Twenty 20 healthy controls were enrolled after ethics approval written informed consent. Synthetic was implemented Siemens 3T...
Rodent models are developed to enhance understanding of the underlying biology different brain disorders. However, before interpreting findings from animal in a translational aspect understand human disease, fundamental step is first have knowledge similarities and differences biological systems studied. In this study, we analyzed verified four known networks termed: default mode network, motor dorsal basal ganglia ventral network using resting state functional MRI (rsfMRI) humans rats. Our...
Objective Magnetic resonance imaging (MRI) is essential for multiple sclerosis diagnostics but conventionally not specific to demyelination. Myelin often hampered by long scanning times, complex postprocessing, or lack of clinical approval. This study aimed assess the specificity, robustness, and value Rapid Estimation Diagnostic Imaging, a new myelin technique based on time‐efficient simultaneous T 1 /T 2 relaxometry proton density mapping in sclerosis. Methods was applied using 3T MRI ex...
Characterize the static and dynamic functional connectivity for subjects with juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach. Whole-brain resting-state MRI data were acquired on 3 T whole-body clinical scanner from 18 clinically diagnosed JME 25 healthy control subjects. 2-min sliding-window approach was incorporated in framework to assess both resting brains. Two-sample t-tests performed voxel-wise detect differences metrics based strength density. The...
The aim of this study is to investigate the feasibility using three-directional velocity encoded 3D gradient echo (GE) phase contrast (PC) imaging assess cerebrospinal fluid (CSF) flow connectivity in human brain. Five healthy volunteers were scanned low sensitivity (V(enc) = 0.04-0.05 m s(-1)). Flow-time curves compared standard 2D PC scans. data used reconstruct vivo CSF volumes based on time-averaged phase-difference information, and patency pathways was assessed nearest-neighbour...