- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Lower Extremity Biomechanics and Pathologies
- Hip disorders and treatments
- Osteoarthritis Treatment and Mechanisms
- Foot and Ankle Surgery
- Nerve Injury and Rehabilitation
- Musculoskeletal synovial abnormalities and treatments
- Musculoskeletal Disorders and Rehabilitation
- Anesthesia and Pain Management
- Bone Tumor Diagnosis and Treatments
- Elbow and Forearm Trauma Treatment
- Hip and Femur Fractures
- Electrical Contact Performance and Analysis
- Cardiovascular Health and Disease Prevention
- Cardiovascular Effects of Exercise
- COVID-19 and healthcare impacts
University of Milano-Bicocca
2016-2025
Ospedale San Pietro Fatebenefratelli
2022-2025
Hôpital Couple Enfant
2020-2025
Université Grenoble Alpes
2019-2025
Sheffield Children's NHS Foundation Trust
2024
Sheffield Children's Hospital
2024
Azienda Ospedaliera San Gerardo
2012-2023
Mayo Clinic in Arizona
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2023
Creative Research Enterprises (United States)
2019
Anterior cruciate ligament (ACL) reconstruction restores knee stability but does not reduce the incidence of posttraumatic osteoarthritis induced by inflammatory cytokines. The aim this research was to longitudinally measure IL-1 β , IL-6, IL-8, IL-10, and TNF- α levels in patients subjected ACL using bone-patellar tendon-bone graft. Synovial fluid collected within 24–72 hours rupture ( acute ), 1 month after injury immediately prior surgery presurgery thereafter postsurgery ). For...
The treatment of anterior cruciate ligament (ACL) injuries in children and adolescents is challenging. Preclinical clinical studies investigated ACL repairing techniques skeletally immature subjects. However, intra-articular bioenvironment following tear has not yet been defined patients. aim this study was to measure cytokine concentrations the synovial fluid adolescent population. Synovial levels IL-1β, IL-1ra, IL-6, IL-8, IL-10, TNF-α were measured 17 patients (15 boys) with tears who...
Abstract Surgical reconstruction of the anterior cruciate ligament (ACL) does not necessarily decrease risk developing osteoarthritis (OA). The inflammatory response and relative changes in pro‐ anti‐inflammatory cytokines could participate triggering development OA. To test this hypothesis we measured concentrations IL‐1β, IL‐1ra, IL‐6, IL‐8, IL‐10, TNF‐α at different times after ACL rupture. sample population consisted 48 patients with tear which were assigned to groups according time...
Sympathetic activation induced by cold pressor test or cigarette smoking is accompanied a marked reduction of radial artery distensibility. It not known, however, whether arterial distensibility under tonic sympathetic restraint, this restraint involves arteries greater than the one in both normal and pathological conditions.We studied continuous ultrasonographic assessment changes diameter over diasto-systolic pressure range (finger measurement) eight patients with Dupuytren disease before...
ABSTRACT Concentrations of pro‐ and anti‐inflammatory cytokines in synovial fluid samples collected from patients with chronic meniscal tears were investigated. An acute inflammatory response is generally reported 24–48 h after knee injury, but the largest body data available literature concerns anterior cruciate ligament injury very little information about balance soluble factors knees tears. Sixty‐nine (46 males 23 females) tear that occurred more than 3 months earlier enrolled. According...
Mesenchymal stromal cells (MSCs), seeded onto a scaffold and associated with platelet-gel, may represent an innovative treatment to improve bone repair. The preparation of MSCs for clinical use requires the fulfillment Good Manufacturing Practice indications. aim this study was validate Practice–grade protocol tissue engineering regeneration, seeding platelet lysate (PL)–cultured hydroxyapatite clinical-grade scaffold. Six large-scale experiments were performed. MSC expansions performed...
Background: Progressive hip displacement is one of the most common and debilitating deformities seen in children with cerebral palsy (CP). The aim this study was to evaluate results temporary medial hemiepiphysiodesis proximal femur (TMH-PF) using a transphyseal screw control migration during growth CP. Methods: This retrospective CP dysplasia, age 4 11 years GMFCS levels III-V. There were 28 patients 56 hips that underwent TMH-PF surgery between 2007 2010. Clinical radiologic evaluation...
In this study, periprosthetic bone mineral density was measured at scheduled time intervals after surgery by dual energy xray absorptiometry in 21 patients to assess the history of redistribution femoral stem insertion. Measurements changes with were obtained for regions greater trochanter, lateral cortex, tip, medial and calcar. all regions, decreased during first 3 months surgery; followed a prolonged period 18 30 gain, subsequent steady state, final resumption aging processes third...
Several open surgical techniques have been used to treat recalcitrant cases of snapping iliotibial band with varying results. Recently, endoscopic become available. The purpose this study was investigate the results a modified release using longitudinal retrospective case series. Fifteen patients (three men and 12 women) symptomatic external hip were treated an band. average age 25 years (range 16-37 years). procedure performed in lateral decubitus position two portals; transversally...
Abstract Purpose The aim of this study was to assess midterm clinical outcomes in Tanner 1–2 patients with proximal anterior cruciate ligament (ACL) tears following arthroscopic-surgical repair using an absorbable or all-suture anchor. Methods Fourteen (9.2 ± 2.9 years-old) 19 skeletally immature reached the 2 years follow-up. Physical examinations included Lachman test, Pivot-shift One-leg Hop Pedi-IKDC as well Lysholm and Tegner activity scores; knee stability measured a KT-1000...