A5045249397- Neuropeptides and Animal Physiology
- Neuroscience of respiration and sleep
- Receptor Mechanisms and Signaling
- Neuroendocrine regulation and behavior
- Inhalation and Respiratory Drug Delivery
- Neuroscience and Neuropharmacology Research
- Regulation of Appetite and Obesity
- Asthma and respiratory diseases
- Sleep and Wakefulness Research
- Pharmacological Receptor Mechanisms and Effects
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Hemophilia Treatment and Research
- Diet and metabolism studies
- CRISPR and Genetic Engineering
- Multiple and Secondary Primary Cancers
- Nutrition and Health Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Synthesis and Properties of Aromatic Compounds
- Consumer Packaging Perceptions and Trends
- Global Cancer Incidence and Screening
- Nicotinic Acetylcholine Receptors Study
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Heme Oxygenase-1 and Carbon Monoxide
Polish Academy of Sciences
2007-2023
Mossakowski Medical Research Institute, Polish Academy of Sciences
2010-2023
University of Warmia and Mazury in Olsztyn
2018-2020
Uniwersytecki Szpital Kliniczny w Olsztynie
2020
Poznan University of Medical Sciences
2019
Jagiellonian University
2012
CRE Consulting (Poland)
2012
Boston Children's Hospital
2002
Etobicoke General Hospital
1998
University of Toronto
1998
Antipsychotics are the gold standard treatment for schizophrenia, but many patients who receive experience persistent symptoms. The aim of this network meta-analysis was to determine efficacy augmentation drugs schizophrenia.
Proteases of Staphylococcus aureus have long been considered to function as important virulence factors, although direct evidence the role particular enzymes remains incomplete and elusive. Here, we sought provide a collective view prevalence extracellular protease genes in genomes commensal pathogenic strains S. their expression course human mouse infection. Data on V8 protease, staphopains A B, aureolysin, recently described poorly characterized group six Spl proteases are provided....
Sulforaphane-modified selenium nanoparticles can be prepared in a simple aqueous-phase redox reaction through reduction of selenite with ascorbic acid. The sulforaphane molecules present the mixture adsorb on nanoparticle surface, forming an adlayer. resulting conjugate was examined several physicochemical techniques, including microscopy, spectroscopy, x-ray diffraction, dynamic light scattering and zeta potential measurements. As shown vivo investigations rats, nanomaterial administered...
The opioid-induced analgesia is associated with a number of side effects such as addiction, tolerance and respiratory depression. involvement neuropeptide FF (NPFF) in modulation pain perception, dependence was well documented contrast to Therefore, the aim present study examine potency NPFF block post-opioid depression, one main adverse opioid therapy. Urethane-chloralose anaesthetized Wistar rats were injected either intravenously (iv) or intracerebroventricularly (icv) various doses prior...
A new tetrahydroacridine derivative (CHDA) with acetylcholinesterase inhibitory properties was synthesized. Using a range of physicochemical techniques, it shown that the compound strongly adsorbs onto surface planar macroscopic or nanoparticulate gold, forming nearly full monolayer. The adsorbed CHDA molecules reveal well-defined electrochemical behavior, being irreversibly oxidized to electroactive species. also exhibits strong fluorescence, which is effectively quenched after adsorption...
The behavioral responses exerted by spinal administration of the opioid-neurotensin hybrid peptide, PK23, were studied in adult male rats. antinociceptive effect upon exposure to a thermal stimulus, as well tolerance development, was assessed an acute pain model. PK23 chimera at dose 10 nmol/rat produced potent pain-relieving effect, especially after its intrathecal administration. Compared with morphine, this novel compound found possess favourable side profile characterized reduced scratch...
Is O 2 diffusivity within renal capillaries rate limiting for delivery to hypoxic tubules? Equations based on diffusion theory and developed here predict that soluble hemoglobin (Hb) increases by a factor of 1 + [442 Hb%/(P 50 +[Formula: see text])], where P is the partial pressure at which Hb half saturated. To examine effect concentrations function, we perfused isolated rat kidneys with Hb-P 35 (P = mmHg) 11 mmHg). Venous[Formula: text] was lower (10 ± vs 16 mmHg arterial [Formula: 28 vs....
A one-step synthesis of tetrathia-, diselenadithia-, and tetraeelenafulvalenes at high pressure from CS2, CSSe, W e 2 , acetylenes substituted with electron withdrawing groups such as COOH, COOCHj CONH2 has been reported.Re- actions CS2 were found to proceed best pressures )4000 atm 75-100DC.Reaction times in excess 10 hours generally employed.CSSe was reacted similarly these acetylene compounds.Lower temperatures (%60DC) needed for reactions involving this is known be more reactive than...