A5103105173- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Musculoskeletal pain and rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Occupational Health and Performance
- Viral Infections and Vectors
- Nutrition and Health in Aging
- Injury Epidemiology and Prevention
- Traffic and Road Safety
- Esophageal and GI Pathology
- Health Promotion and Cardiovascular Prevention
- Knee injuries and reconstruction techniques
- Global Public Health Policies and Epidemiology
- Insect and Pesticide Research
- Trauma and Emergency Care Studies
- Mosquito-borne diseases and control
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Parasites and Host Interactions
- Folate and B Vitamins Research
- Osteoarthritis Treatment and Mechanisms
University of Kelaniya
2013-2024
Faculty (United Kingdom)
2013
University of Sri Jayewardenepura
2011
To compare the prevalence of disabling low back pain (DLBP) and wrist/hand (DWHP) among groups workers carrying out similar physical activities in different cultural environments, to explore explanations for observed differences, we conducted a cross-sectional survey 18 countries. Standardised questionnaires were used ascertain that interfered with everyday exposure possible risk factors 12,426 participants from 47 occupational (mostly nurses office workers). Associations assessed by Poisson...
To explore definitions for multisite pain, and compare associations with risk factors different patterns of musculoskeletal we analysed cross-sectional data from the Cultural Psychosocial Influences on Disability (CUPID) study. The study sample comprised 12,410 adults aged 20-59 years 47 occupational groups in 18 countries. A standardised questionnaire was used to collect information about pain past month at each 10 anatomical sites, potential factors. Associations outcomes were assessed by...
Abstract Background and Aims To improve upon the estimation of 10-year cardiovascular disease (CVD) event risk for individuals without prior CVD or diabetes mellitus in Asia-Pacific region by systematic recalibration SCORE2 algorithm. Methods The sex-specific competing risk-adjusted algorithms were systematically recalibrated to reflect incidence observed four regions, defined according country-level World Health Organization age- sex-standardized mortality rates. Using same approach as...
Sri Lanka reports significantly more cutaneous leishmaniasis (CL) cases than visceral (VL) cases, both of which are caused by Leishmania donovani MON-37. A cross-sectional study conducted in an area with a high prevalence CL prevalent included 954 participants estimated population 61,674 to estimate the number ascertain whether there is pool asymptomatic VL and identify risk factors for transmission. total 31 were identified, whom 21 previously diagnosed 10 new cases. Using rK39 rapid...
Cutaneous leishmaniasis (CL) in Sri Lanka is caused by Leishmania donovani. This study assessed the diagnostic value of a new rapid immunochromatographic strip (CL-Detect™ IC-RDT), that captures peroxidoxin antigen amastigotes.We sampled 74 clinically suspected CL lesions, which 59 (79.7%) were positive PCR, 43 (58.1%) Giemsa stained slit skin smear (SSS) and 21 (28.4%) IC-RDT. All samples either SSS or IC-RDT both PCR. The sensitivities compared to PCR 36% 73%, respectively. Fifteen...
Abstract The endemic strain of Leishmania donovani in Sri Lanka causes cutaneous leishmaniasis (CL) rather than more common visceral form. We have visualized biofilms and profiled the microbiome lesions unaffected skin thirty-nine CL patients. Twenty-four (61.5%) were biofilm-positive according to fluorescence situ hybridization. Biopsies dominated by Pseudomonas , class Bacilli Enterobacteriaceae distinguished significantly lower community evenness. Higher relative abundance a OTU was...
Cutaneous leishmaniasis (CL) is endemic in Sri Lanka. Giemsa-stained slit-skin-smears (SSS-Giemsa) and histology are routinely used diagnosis with a sensitivity of 40–70%. PCR currently has limited accessibility. Therefore, we assessed the specificity previously described fluorescence situ hybridization assay, on skin smears biopsy samples to overcome limitations encountered routine diagnostic methods.
To determine the association between hyperhomocysteinaemia and coronary artery disease (CAD) in a sample of Sri Lankans.A case control study.Asiri Hospital, Kirula Road, Colombo 5, Lanka.105 patients with 112 controls.Fasting serum homocysteine levels were measured 105 diagnosed as having CAD unmatched controls. All admitted clinical, electrocardiographical, biochemical or echocardiographical evidence included study. Controls selected from subjects for health screening.105 controls...
Knee Injury and Osteoarthritis Outcome Score (KOOS) scale is a patient-reported outcome measurement tool. It evaluates both short- long-term consequences of knee injury primary osteoarthritis. This study aims to translate validate the KOOS for Sinhala-speaking Sri Lankan population. A cross sectional was conducted in three hospitals. Four hundred fifteen patients comprising 185 males 227 females (3 subjects did not reveal their gender) with osteoarthritis (KOA) participated study. Seventy...
Road traffic crashes (RTC) and consequent injuries constitute a global threat to public health disproportionately borne by low-and-middle-income countries. With rapid urbanisation increased motorisation, RTC is identified as one of the leading causes death injury in Sri Lanka. This study aimed describe crash characteristics patterns among victims RTCs admitted tertiary-care state hospital Colombo, capital Recorded data on all Colombo South Teaching Hospital from 01.01.2017 31.03.2017 were...
Mobility and social participation greatly enhance the well-being quality of life older adults. A rapid increase in populations together with comorbidities process ageing have important implications for transport policies globally, especially low-and-middle-income countries. This study aimed to explore adults' travel behaviours challenges safety Sri Lanka, where demographic transition non-communicable disease burden make people those living disability particularly vulnerable road traffic...