- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Sodium Intake and Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Epigenetics and DNA Methylation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutritional Studies and Diet
- Health Systems, Economic Evaluations, Quality of Life
- Health Promotion and Cardiovascular Prevention
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- RNA modifications and cancer
- Cardiac Arrest and Resuscitation
- Colorectal Cancer Treatments and Studies
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Cardiac and Coronary Surgery Techniques
Hanoi Medical University
2011-2025
Bạch Mai Hospital
2011-2025
National Hospital of Pediatrics
2019-2025
Novartis (Switzerland)
2025
Novartis Institutes for BioMedical Research
2025
Institute of Mathematics
2024
Ho Chi Minh City Medicine and Pharmacy University
2024
National Economics University
2024
General Hospital of Shenyang Military Region
2021
Alberta Hospital Edmonton
2021
Abstract Background and Aims To improve upon the estimation of 10-year cardiovascular disease (CVD) event risk for individuals without prior CVD or diabetes mellitus in Asia-Pacific region by systematic recalibration SCORE2 algorithm. Methods The sex-specific competing risk-adjusted algorithms were systematically recalibrated to reflect incidence observed four regions, defined according country-level World Health Organization age- sex-standardized mortality rates. Using same approach as...
The ribosomal genes ( rDNA genes) encode 47S rRNA which accounts for up to 80% of all cellular RNA. At any given time, no more than 50% are actively transcribed, and the other half is silent by forming heterochromatin structures through DNA methylation. In cancer cells, upregulation ribosome biogenesis has been recognized as a hallmark feature, thus, reduced methylation promoter thought support conformational changes chromatin accessibility subsequent increase in transcription. However, an...
A 73-year-old woman developed abdominal distention, pain with pallor, and hypotension after successful primary percutaneous coronary intervention 1 drug-eluting stent. Emergent blood tests imaging confirmed right perirenal hemorrhage. Selective renal angiogram revealed ongoing bleeding from a distal artery perforation when her clinical condition deteriorated despite conservative management. vascular plug device was deployed in branch supplying the area, because direct access to perforated...
Ziel/Aim: In VISION, [177Lu]Lu-PSMA-617 (177Lu-PSMA-617) plus standard of care (SoC) significantly improved overall survival and radiographic progression-free in patients (pts) with PSMA-positive metastatic castration-resistant prostate cancer. the VISION dosimetry sub-study, 177Lu-PSMA-617 had a good safety profile low radiotoxicity. Here, we present tumor for across cycles 1-6.
Background. Data on cardiovascular disease risk factors (CVDRFs) in Vietnam are limited. This study explores the prevalence of each CVDRF and how they cluster to evaluate burdens potential prevention strategies. Methods. A cross-sectional survey 2009 (2,130 adults) was done collect data behavioural CVDRF, anthropometry blood pressure, lipidaemia profiles, oral glucose tolerance tests. Four metabolic CVDRFs (hypertension, dyslipidaemia, diabetes, obesity) five (smoking, excessive alcohol...
Health promotion is a key component for primary prevention of cardiovascular disease (CVD). This study evaluated the impact healthy lifestyle campaigns on CVD risk factors (CVDRF) in general population context community-based programme hypertension management. A quasi-experimental intervention was carried out two rural communes Vietnam from 2006 to 2009. In commune, hypertensive-targeted management integrated with community-targeted health initiated, while no new programme, apart...
Costly efforts have been invested to control and prevent cardiovascular diseases (CVD) their risk factors but the ideal solutions for low resource settings remain unclear. This paper aims at summarising our approaches implementing a programme on hypertension management in rural commune of Vietnam. In commune, has implemented since 2006 manage hypertensive people health station deliver education CVD entire community. An initial cross-sectional survey was used screen hypertensives who might...
Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe stenosis (AS) and the uptake of TAVI is rapidly growing Asia-Pacific region. However, there exist a heterogeneity management use among countries Reasons for these differences include anatomic variations, disparity healthcare resources infrastructure, lack consensus on optimal AS Hence, Asian Pacific Society Cardiology (APSC) working group, including multidisciplinary...
The aim of this study was to explore the impact frailty on in-hospital adverse outcomes and net clinical events (NACE) in older patients with acute coronary syndrome.This observational included elderly (≥60 years old), diagnosed syndrome (ACS) at admission from February 2021 August 2021. primary outcome defined as a composite all-cause mortality, stroke, major bleeding. Secondary including arrhythmia, acquired pneumonia, bleeding, mortality. Frailty assessed using Frail scale (FS). Data...
Background Cardiovascular disease is one of the leading causes morbidity and mortality in Vietnam. We conducted a pilot study Hanoi residents hospitalized with acute myocardial infarction (AMI) at Vietnam National Heart Institute Hanoi. The objectives this observational were to examine sex differences clinical characteristics, hospital management, in-hospital complications, patients an initial AMI. Methods population consisted 302 first AMI largest tertiary care medical center 2010. Results...
The 16q12.2 locus in the first intron of FTO has been robustly associated with body mass index (BMI) and type 2 diabetes genome-wide association studies (GWAS). To improve resolution fine-scale mapping at FTO, we performed a systematic approach consisting two parts.The part is to partition variants into linkage disequilibrium (LD) clusters, followed by conditional haplotype analyses. second filter list potential causal through trans-ethnic comparison.We examined LD relationship between SNPs...
Objectives The impact of the COVID-19 pandemic on treatment patient with aortic valve stenosis is unknown and there uncertainty optimal strategies in managing these patients. Methods This study supported endorsed by Asia Pacific Society Interventional Cardiology. Due to inability have face discussions during pandemic, an online survey was performed inviting key opinion leaders (cardiac surgeon/interventional cardiologist/echocardiologist) field transcatheter implantation (TAVI) participate....
Little is known about percutaneous coronary intervention (PCI) practices and outcomes in low-and middle-income nations, despite its rapid uptake across Asia. For the first time, we report on clinical characteristics in-hospital for patients undergoing PCI at a leading cardiac centre Vietnam.
Data regarding the health-related quality of life (HRQoL) in men and women after percutaneous coronary intervention (PCI) low-and-middle incomes countries remains scarce. To investigate sex difference HRQoL at 30 days 12 months post PCI Vietnam.We used data from a single registry established Vietnam National Heart Institute. The was measured using EQ-5D-3L instrument via telephone interviews, information about demographics, clinical presentation procedures obtained through face-to-face...
<strong>Background:</strong> In lower- and middle-income countries across Asia there has been a rapid expansion uptake of percutaneous coronary intervention (PCI). However, limited routine collection related data, particularly around quality, safety cost. The aim this study was to assess the viability implementing PCI data in registry at leading hospital Hanoi, Vietnam. <strong>Method:</strong> A Vietnamese form strategy were developed collaboration with Vietnam National Heart Institute....
Neuroendocrine cervical cancer is a rare subtype of with highly aggressive malignancy. This study was conducted to analyse the human papillomavirus (HPV) infection and molecular abnormalities in Vietnamese neuroendocrine carcinomas uterine cervix. HPV genotyping p53 mutations were examined using polymerase chain reaction (PCR)-based direct sequencing. Mutations epidermal growth factor receptor (EGFR), Kirsten rat sarcoma (KRAS), neuroblastoma RAS viral oncogene homolog (NRAS) v-Raf murine B...
BackgroundLittle is known about rates of access site (transradial (TRI) or transfemoral (TFI)) preference for percutaneous coronary intervention (PCI) and in-hospital costs patients undergoing these procedures in lower-and middle-countries. Here, we report on use, outcomes PCI Vietnam.MethodsInformation from 868 were included the cohort 1022 recruited into first registry Vietnam. The total hospital TRI TFI compared. Hospital obtained admission system, major adverse cardiac events, bleeding...