A5068586130- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Cardiac pacing and defibrillation studies
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Mechanical Circulatory Support Devices
- Health Systems, Economic Evaluations, Quality of Life
- Hemodynamic Monitoring and Therapy
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Transplantation: Methods and Outcomes
- Pericarditis and Cardiac Tamponade
- Cardiac tumors and thrombi
Duke-NUS Medical School
2010-2025
National Heart Centre Singapore
2016-2025
Sengkang General Hospital
2025
AstraZeneca (Poland)
2024
Medtronic (Ireland)
2024
Biotronik (Switzerland)
2024
Boston Scientific (United States)
2024
Novartis (Switzerland)
2024
Terumo (Japan)
2024
University of Connecticut
2021
Background: Current-generation zotarolimus-eluting stents (ZES) have been shown to be an effective choice for percutaneous coronary intervention. However, data comparing real-world clinical outcomes between ZES and other stent platforms (non-ZES) are limited. We aim compare of patients receiving versus non-ZES during intervention based on our centre’s registry. Methods: This was a non-randomised, non-blinded, all-comers observational registry in treated with (control). The primary endpoint...
Dear Editor, Myocardial infarction with non-obstructive coronary artery disease (MINOCA) occurs in up to 14% of patients presenting acute syndrome (ACS).1 Clinically, such present ACS symptoms, elevation troponin and angiograms showing arteries (<50% stenosis).2 MINOCA has myriad aetiologies which are classified according (i.e. embolism, spasm or spontaneous dissection) non-coronary pathologies trauma myocarditis).3
We report a series of operated tetralogy Fallot (TOF) patients focusing on complications and outcomes.Data from TOF seen at our centre's adult congenital heart disease clinic was analysed.There were 21 patients: the mean age 32.2 +/- 12.4 years; first operation 9.0 7.9 postoperative follow-up duration 23.5 12.1 current New York Heart Association (NYHA) status: I, 82%; II, 4%; III, 14%. Fourteen had complete operative notes. All these underwent total correction; 2 staged aortopulmonary shunt...
Transcatheter aortic valve implantation (TAVI) has been established as an effective treatment modality in patients with severe stenosis (AS) and the uptake of TAVI is rapidly growing Asia-Pacific region. However, there exist a heterogeneity management use among countries Reasons for these differences include anatomic variations, disparity healthcare resources infrastructure, lack consensus on optimal AS Hence, Asian Pacific Society Cardiology (APSC) working group, including multidisciplinary...
To assess the clinical and angiographic outcomes of coronary intravascular lithotripsy (IVL) use in an all-comers population with moderate-to-severely calcified lesions.
Transcatheter aortic valve replacement (TAVR) is increasingly performed. Physically small Asians have smaller root and peripheral vessel anatomy. The influence of gender Asian patients undergoing TAVR unknown may affect outcomes. aim this study was to assess sex differences in TAVR.Patients from eight countries were enrolled. In retrospective analysis, we examined characteristics, 30-day clinical outcomes 1-year survival between female male patients.Eight hundred seventy-three (54.4% women)...
Aims:The aim of the study was to report clinical experience, 30-day mortality and acute outcomes patients undergoing transcatheter aortic valve implantation (TAVI) in Asia Pacific region. Methods results:The TAVI registry is an international, multicentre, prospective, observational managed under auspices Asian Society Interventional Cardiology (APSIC).Patients seven centres from Hong Kong, Japan, Philippines, Singapore Taiwan, treated with devices for severe symptomatic stenosis, were...
Background: The use of cerebral embolic protection devices during transcatheter aortic valve implantation (TAVI) reveals conflicting data.Aims: This updated meta-analysis aims to evaluate the efficacy and safety SENTINEL Cerebral Protection System.Methods: A literature search for relevant studies up September 2022 was performed.Study outcomes were divided based on time period -overall (up 30 days) short (≤7 days).The studied include stroke (disabling, non-disabling), mortality, neuroimaging...
Background: Heavily calcified coronary artery lesions are a therapeutic challenge for interventional cardiologists worldwide. Recently, RotaTripsy has gained popularity as calcium modification technique prior to stent implantation. In this procedure, operators employ rotational atherectomy debulk luminal alongside intravascular lithotripsy fracture deeper concentric calcifications. Aims: To identify the demographics and outcomes of patients undergoing RotaTripsy. Methods: Baseline clinical...
Aging-related cardiovascular disease and frailty burdens are anticipated to rise with global aging. In response directions from major societies, we investigated knowledge, awareness, practices among cardiologists as key stakeholders in this emerging paradigm a year after the European Frailty Cardiology consensus document was published.
Stress cardiovascular magnetic resonance (CMR) offers assessment of ventricular function, myocardial perfusion and viability in a single examination to detect coronary artery disease (CAD). We developed an in-scanner exercise stress CMR (ExCMR) protocol using supine cycle ergometer aimed examine the diagnostic value multiparametric approach patients with suspected CAD, compared invasive fractional flow reserve (FFR) as reference gold standard. In this single-centre prospective study, who had...
A retrospective case series of acute anterior myocardial infarction (MI) patients complicated by complete atrioventricular block (AVB) treated with percutaneous transluminal coronary angioplasty (PTCA).Eight MI and AVB underwent PTCA between 2000 2005. Mean onset was 16.6 +/- 16.9 hours from chest pain onset.All successful to the left descending artery.Complete resolved in 88%; mean time resolution 89 144 minutes after revascularisation. One patient had permanent pacemaker implanted at Day...
Introduction: Chronic kidney disease (CKD) is a significant comorbidity in aortic stenosis (AS) patients. We examined the impact of baseline CKD, postoperative acute injury (AKI) and CKD progression on clinical outcomes patients who underwent transcatheter valve implantation (TAVI). Materials Methods: Consecutive with severe AS TAVI were classified into stages 1–2 (≥60 mL/min/1.72m2), 3 (30–59 mL/min/1.73m2) 4–5 (<30 mL/min/1.73m2 or dialysis) based estimated glomerular filtration rate...
The objective was to assess the cost-effectiveness of transcatheter aortic valve implantation (TAVI) in patients with severe stenosis intermediate surgical risk Singapore.A de novo Markov model three health states - stroke long-term sequelae, no stroke, and death developed simulated using Monte Carlo simulations 10,000 iterations over a five-year time horizon from Singapore healthcare system perspective. A 3% annual discount rate for costs outcomes monthly cycle lengths were used. By...
Data on patients with small aortic annuli (SAA) undergoing transcatheter valve implantation (TAVI) are limited. We aim to describe the impact of annular size, particularly SAA and TAVI type haemodynamics, durability clinical outcomes.All in National Heart Centre Singapore who underwent transfemoral for severe symptomatic native stenosis from July 2012 December 2019 were included. Outcome measures include prosthesis-patient mismatch (PPM), structural degeneration (SVD) mortality.A total 244...
An 80-year-old patient complained of 1 week history progressive exertional dyspnoea. The had a traumatic right pubic ramus fracture following fall month before admission. On clinical examination, there was evidence heart failure. electrocardiogram demonstrated normal sinus rhythm with rate 80 beats/min and an old anterior infarct. chest radiograph unremarkable. Transthoracic echocardiography showed severely dilated atrium ventricle (RV). A distinctive feature RV dysfunction, akinesia free...