- Bacterial Infections and Vaccines
- Spectroscopy Techniques in Biomedical and Chemical Research
- Pneumonia and Respiratory Infections
- Biosensors and Analytical Detection
- Antifungal resistance and susceptibility
- Listeria monocytogenes in Food Safety
- Fungal Infections and Studies
- Photonic and Optical Devices
- Salmonella and Campylobacter epidemiology
- Infective Endocarditis Diagnosis and Management
- Virology and Viral Diseases
- Rabies epidemiology and control
- Pediatric health and respiratory diseases
- Orthopedic Surgery and Rehabilitation
- Legionella and Acanthamoeba research
- Infectious Diseases and Mycology
- Brucella: diagnosis, epidemiology, treatment
- Medical and Biological Ozone Research
- Bacillus and Francisella bacterial research
- Botulinum Toxin and Related Neurological Disorders
- Advanced Biosensing Techniques and Applications
- Systemic Sclerosis and Related Diseases
- Animal Ecology and Behavior Studies
- Yersinia bacterium, plague, ectoparasites research
- Gold and Silver Nanoparticles Synthesis and Applications
Infectious Clinical Hospital No. 1
2008-2023
Using a micro-hole grating in supported silver film as laser-fabricated novel optical platform for surface-enhanced IR absoprtion/reflection spectroscopy, characteristic absorption bands of Staphylococcus aureus, particular, its buried carotenoid fragments, were detected FT-IR spectra with 10-fold analytical enhancement, paving the way spectral express-identification pathogenic microorganisms.
Invasive pneumococcal disease remains one of the leading causes morbidity and mortality worldwide. In Russia, 13- valent conjugate vaccine (PCV13) was introduced into childhood immunization programme nationwide in 2014. As part Global Pneumococcal Sequencing Project (GPS), we used genome data to characterize 179 isolates collected from Russia 2011-2018 investigate circulating strains using a standardized genomic definition lineages (global sequence clusters, GPSCs), prevalent serotypes...
This work is devoted to the study of a single Staphylococcus aureus bacterium detection using surface-enhanced Raman spectroscopy (SERS) and resonant (RS). It was shown that SERS allows increasing sensitivity predominantly low frequency lines connected with vibrations Amide, Proteins DNA. At same time carotenoids inherent this kind are well-detected due resonance scattering mechanism. The reproducibility stability spectra strongly depend on characteristics nanostructured substrate, molecular...
Early diagnostics of meningitis is a very topical problem as it fulminant disease with high level mortality. The progress this is, rule, accompanied by the appearance bacteria in cerebrospinal fluid (CSF) composition. examination CSF well known to be only reliable approach identification meningitis. However, traditional biochemical analyses are time consuming and not always reliable, simple, inexpensive, whereas optical methods poorly developed. This work devoted study Raman spectra several...
To study the main causes of severe course and high mortality in patients with nervous form listeriosis.The analysis Listeria meningoencephalitis (LM) 36 aged from 9 to 85 years, who were treated Infectious clinical hospital No. 2 DZM (IKB DZM). Along standard examination methods, blood cerebrospinal fluid (CSF) polymerase chain reaction tests performed identify monocytogenes. The sensitivity pathogen antibiotics was determined by serial dilutions on WalkAway 96 Plus device Siemens, USA.LM...
The purpose of research - the study clinical and pathogenetical features cryptococcal meningoencephalitis (CME) in patients with HIV infection for improvement efficiency diagnosis treatment. Materials Methods. There are presented results 67 cases infection. was performed an assessment picture cerebrospinal fluid (CSF), which consisted direct microscopy, cultural method PCR. Also pathomorphological data deceased have been analyzed. Results study. CME mildly pronounced not constant. Dominant...
Objective To study the etiological structure of disease in patients with various forms erysipelas lower extremities by using bacteriological method. Materials and methods A total 50 in-patients limbs, mainly bullous hemorrhagic form, were examined. Using method we examined blood, smears from skin area hearth bulls punctate. The demonstrated preferential identification staphylococcus, - skin, while informativeness blood culture punctate was low. Conclusion positive results research can serve...
Using a micro-hole grating in supported silver film as laser-fabricated novel optical platform for surface-enhanced IR absoprtion/reflection spectroscopy, characteristic absorption bands of Staphylococcus aureus, especially – its buried carotenoid fragments were detected FT-IR spectra with 10-fold analytical enhancement, paving the way to spectral express-identification pathogenic microorganisms.
Background: The interepidemic meningococcal infection (MI) period in Moscow has been going since the 1989. Outbreaks of general forms MI (GFMI) were registered 1996, 2003, 2008 with their morbidity rates per 100,000 persons (MR) 4.23, 3.63 and 2.59. In 2012 MR was at 1.56. Methods & Materials: Meningococcus strains isolated from GFMI patients Infectious Diseasaes Clinic serogrouped, specifics immunological structure population defined. Results: predominance serogroup A (MSA) shown. highest...
Aim: To identify the signs and reasons why listeriosis can be classified as opportunistic infections in HIV infection, requiring timely diagnosis treatment to prevent development of a severe course disease minimize risks death. Materials methods: 38 hospitalized patients with meningitis/ meningoencephalitis were examined. All boxed departments neuroinfections (the infection was not known) directional meningitis unclear etiology, where, according Meningitis program, PCR examination for L....
Despite the low level of morbidity, significance meningococcal infection (MI) persists and is primarily due to predicted rise in morbidity after a long period relative well-being (decline), instability serogroup landscape, an increase caused by previously rare serotypes (meningococcus W), lack routine vaccination, as well severe course, development formidable complications high risk death. The up 30–60 % disabling generalized forms (GFMI), including physical neuropsychiatric problems, also...