A5076334632- HIV, TB, and STIs Epidemiology
- HIV, Drug Use, Sexual Risk
- SARS-CoV-2 and COVID-19 Research
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Long-Term Effects of COVID-19
- HIV/AIDS drug development and treatment
- Blood groups and transfusion
- Immunodeficiency and Autoimmune Disorders
- Hepatitis B Virus Studies
- COVID-19 epidemiological studies
- Cytomegalovirus and herpesvirus research
- HIV-related health complications and treatments
- Sex work and related issues
- Neurological and metabolic disorders
- Sarcoidosis and Beryllium Toxicity Research
- Eosinophilic Esophagitis
- Adrenal Hormones and Disorders
- Parvovirus B19 Infection Studies
- Viral gastroenteritis research and epidemiology
- HIV/AIDS Impact and Responses
- Medical and Agricultural Research Studies
Regional Center for Prevention and Control of AIDS and Infectious Diseases
2016-2024
Infectious Clinical Hospital No. 1
2015-2023
Centre for Prevention and Control of AIDS and Infectious Diseases
2015-2022
Regional Research Centres
2011
The aim of the study: to analyse diagnostic trends HIV-infection in Russian Federation period 2017–2022. Materials and methods. study used data obtained from reports Federal Register persons infected with human immunodeficiency virus (FRHIV). circumstances HIV diagnosis clinical epidemiological characteristics newly diagnosed patients, including CD4+ T-lymphocyte counts, were analysed. A likely time window between presumed infection confirmation was also determined. Categorical evaluated...
HIV-infection is known to aggravate the course of many infectious diseases, including COVID-19. International guidance recommends vaccination HIV+ individuals against SARS-CoV-2. There a paucity data on epidemiological efficacy assessment COVID-19 vaccines among HIV+. This paper provides preliminary Sputnik V vaccine effectiveness in patients antiretroviral therapy (ART).We performed retrospective cohort study assess standard regimen 24,423 Moscow residents during spring - summer 2021, that...
Because of the constantly growing numbers COVID-19 infections and deaths, attempts were undertaken to find drugs with anti-SARS-CoV-2 activity among ones already approved for other pathologies. In framework such attempts, in a number vitro , as well vivo models it was shown that hydroxychloroquine (HCQ) has an effect against SARS-CoV-2. While there not enough clinical data support use HCQ, several countries including Russia have included HCQ treatment protocols infected patients prophylaxis....
HIV infection is associated with the increased risk of cardiovascular disease (CVD), even in patients successfully treated combination antiretroviral therapy (cART). However, relationship between HIV, cART, and pathogenesis CVD remains controversial. In present study, we evaluated carotid intima-media thickness (CIMT), a surrogate marker atherosclerosis, HIV-infected subjects receiving or not cART. One hundred nine newly diagnosed one uninfected age-matched controls (all males) without...
Abstract With the progress of COVID-19 studies, it became evident that SARS-CoV-2 infection is often associated with thrombotic complications. The goal our present study was to evaluate which component clot formation process including endothelial function, platelets aggregation and plasma coagulation, as well endogenous fibrinolysis in patients correlates severity disease. We prospectively included 58 47 healthy volunteers a control group we recruited before pandemic started. It turns out...
The present article deals with the problems pertaining to forensic medical diagnostics of HIV-associated pathological conditions taking into consideration materials available from Moscow City Centre for AIDS Prophylaxis and Control special reference number structure diagnosed diseases. We undertook analysis co-morbid HIV/AIDS causes violent sudden deaths documented at Bureau Forensic Medical Expertise Health Department during period 2013 till 2016. study revealed tendency toward a rise in...
Introduction.The development of the COVID-19 pandemic along with ongoing HIV infection has raised question how these two diseases interact. This study examines morphological changes that occur in lung tissue during HIV/SARS-CoV-2 coinfection patients varying levels immune status. Materials and methods. The included 6 deceased HIV-infected who had a clinical diagnosis COVID-19, which was confirmed postmortem by detection SARS-CoV-2 RNA samples obtained biopsy using polymerase chain reaction....
РезюмеВ клиническом наблюдении представлены случай ятрогенного синдрома Кушинга у пациента
Background: current epidemiological data indicates that neurocognitive disorders linked to human immunodeficiency virus (HIV) infection have a prevalence as high 23.5%. The establishment of latent HIV reservoir within the central nervous system (CNS) is implicated in pathogenesis HIV-related lesions, both prior and during antiretroviral therapy (ART). Aim: this study aims investigate etiological factors contributing CNS damage associated with patients receiving ART. Materials Methods:...
Significance. The structure of drug use in the Russian Federation (injectable, non-injectable, psychoactive and others) is undergoing changes, which may affect ratio HIV transmission routes. These changes epidemic process require further research to form adequate measures counter spread infection Federation. purpose study was identify specific features correlation between addiction incidence Russia describe their role influence on at present stage. Material Methods. used data federal...
The course of two pandemics (syndemic) — HIV & COVID-19, demonstrated the synergistic eff ect SARS-CoV-2 on human body. aim study was to identify features diagnosis, course, treatment and outcomes coronavirus infection (COVID-19) in infected patients admitted an infectious hospital. Materials methods: retrospective data 1,250 with COVID-19/HIV coinfection ICH No. 2 Moscow 2021 have been analyzed. Laboratory instrumental diagnostics were carried out clarify diagnosis severity condition....
The aim of the work is to improve algorithm management pregnant women with HIV/HCV co-infection. study was conducted on basis Moscow City Center for AIDS Prevention and Control Department Health from 2020 2022. 80 diagnosed coinfection were under observation. patients underwent a general examination evaluation anamnesis data, laboratory tests. article presents statistical data HIV/HCV-infected who have been registered at past three years. social characteristics co-infection are given...
Abstract Due to the constantly growing numbers of COVID-19 infections and death cases attempts were undertaken find drugs with anti SARS-CoV-2 activity among ones already approved for other pathologies. In framework such attempts, in a number vitro, as well vivo, models it was shown that hydroxychloroquine (HCQ) has an effect against SARS-CoV-2. While there not enough clinical data support use HCQ, several countries including Russia have included HCQ treatment protocols infected patients...
The goal was to establish the frequency of detection LPS O antigens common causative agents intestinal infections in HIV-infected patients at stage secondary diseases. Materials and methods. study included 48 4A, 4Б, 4B (25 men 23 women), without diarrhea, a mean age ofpatients 36,78 ± 7,8 years. Stool samples (2-4 from patient interval 5-7 days) were studied for presence LPS/O-antigens S.sonnei, S.flexneri 1-5, 6, Salmonella sgr. B, C1, C2, D, E, Y.pseudotuberculosis I, III,...
Особенности течения ВИЧ-инфекции неизменно представляют интерес для широкого круга клиницистов.Цель работы -описание и характеристика пациентов из разных групп спонтанной «непрогрессии» ВИЧ-инфекции.Материал методы.В качестве примеров обсуждения приведены результаты наблюдения за пациентами, состоящими на учете в МГЦ СПИД, чьи особенности инфекции укладываются рамки «непрогрессии».Выделена группа 31 пациента: 15 элитных контроллеров, 12 ВИЧ-контроллеров 4 контроллера виремии.Дана каждой...
SARS-CoV-2 pandemic is now a global medical and social problem. Little known about its impact on some vulnerable subgroups, such as immunocompromised patients. Therefore, there still strong interest in exploring the of infection among HIV-positive individuals worldwide. Aim study: to analyze immunological aspects deceased patients with HIV/COVID-19 coinfection. Materials methods. We provided retrospective analysis 258 patient’s electronic records. All were admitted Infectious diseases...
The objective of the study: to establish specific parameters for formation tuberculosis risk group in HIV positive children 0-17 years old order plan prevention activities. Subjects and methods. main statistical rates on tuberculosis, infection their combination 2009-2018 were studied. All new cases TB/HIV co-infection analyzed Moscow 2004-2018. Results. While incidence among has been decreasing over a 10-year period (2009-2018), with advanced develop due is growing, both born by women (by...
Background: HIV infection is a known factor that aggravates the clinical course of many infectious diseases including COVID-19. The international guidance suggests benefits from preventive SARS-CoV-2 vaccination using products with proven efficacy overweigh potential risks for HIV-infected people. However, there little data on epidemiological assessment COVID-19 vaccines among This paper provides preliminary Sputnik V (Gam-COVID-Vac) vaccine effectiveness in patients under antiretroviral...
The aim of the study is to analyze experience Moscow Center for HIV/AIDS Prevention and Treatment on antiviral therapy chronic hepatitis C in patients with HIV/ HCV coinfection real-world evidence (RWE). Methods . data from outpatient cards 12 adults 53 children HIV/HCV were analyzed period 2020 October 2021. In addition standard laboratory tests, viral load HIV RNA, RNA was examined all patients, genotype determined, degree liver fibrosis assessed by fibroelastometry. Results : Among adult...
The cohort of patients co-infected with HIV and HCV needs a special approach to monitoring treatment. combination these infectious pathologies negatively effects the prognosis complicates therapy. At same time, majority HIV/HCV are injecting drug users, which further their involvement in treatment process. Modern strategies for by using new classes antivirals will simplify increase frequency SVR. In Russia, according official statistics, number infection 2014 was 742,611 people. Of these,...
Aim: To identify the signs and reasons why listeriosis can be classified as opportunistic infections in HIV infection, requiring timely diagnosis treatment to prevent development of a severe course disease minimize risks death. Materials methods: 38 hospitalized patients with meningitis/ meningoencephalitis were examined. All boxed departments neuroinfections (the infection was not known) directional meningitis unclear etiology, where, according Meningitis program, PCR examination for L....
The data of medical records 43 HIV-infected pregnant women and 46 children analyzed for the period from 2017 to 2022. average age was 33 years (33.6 ± 0.89). Many (86.0%) had sexual transmission HIV. duration HIV infection in more than half cases (51.1%) 6 years. HIV/HCV co-infection diagnosed 27.9% women. 29 received rilpivirine/ tenofovir/emtricitabine before pregnancy. 14 patients ART regimens, including 2NRTIs NNRTIs or Pis, were switched rilpivirine/tenofovir/emtricitabine during During...