A5100406087- Corneal Surgery and Treatments
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Vitamin D Research Studies
- Viral Infections and Immunology Research
- Immune Response and Inflammation
- Natural Compounds in Disease Treatment
- Analog and Mixed-Signal Circuit Design
- Natural product bioactivities and synthesis
- Mycobacterium research and diagnosis
- Vitamin C and Antioxidants Research
- Vector-Borne Animal Diseases
- Monoclonal and Polyclonal Antibodies Research
- Leprosy Research and Treatment
- Therapeutic Uses of Natural Elements
- RNA and protein synthesis mechanisms
- Viral Infections and Vectors
- Psoriasis: Treatment and Pathogenesis
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- EEG and Brain-Computer Interfaces
- ECG Monitoring and Analysis
- Corneal surgery and disorders
Tianjin Medical University
2023-2024
Xi'an Jiaotong University
2024
Shandong University of Technology
2023
Peking Union Medical College Hospital
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Beijing Information Science & Technology University
2021
Inner Mongolia Medical University
2019
Beijing Center for Disease Prevention and Control
2011
Chinese Academy of Medical Sciences Dermatology Hospital
1986
Millions of individuals across the world suffer from corneal stromal diseases that impair vision. Fortunately, three-dimensional (3D) bioprinting technology which has revolutionized field regenerative tissue engineering makes it feasible to create personalized corneas. In this study, an artificial cornea with a high degree precision, smoothness, and programmable curvature was prepared by using digital light processing (DLP) 3D in one piece no support structure, construct then confirmed...
Corneal damage contributes to blindness in millions of people. Simulating natural corneas with artificial is challenging due material and manufacturing limitations, including poor mechanical properties, complex processes, ocular histocompatibility. In this study, electrospun micro-nanofibrous decellularized extracellular matrix (dECM) combined digital light processing 3D bioprinting validated as a bioartificial cornea for the first time. Electrospinning gives controllable shape, dECM,...
Given the serious neurological complications and deaths associated with enterovirus 71 (EV71) infection, there is an urgent need to develop effective antivirals against this viral infection. In study, we demonstrated that two Cathelicidin-derived peptides, LL-18 FF-18 were more potent EV71 infection than parent peptide LL-37, which mature processed form of Cathelicidin. These peptides could directly bind virus particles, but not coxsackievirus, indicative their high specificity. The binding...
Objective To investigate the carriage of novel Bunyavirus among rodents,canines and ticks in Beijing area,to explore animal host transmission vector which possibly exists nature for Bunyavirus,analyze possibility natural epidemic focus place existence area Bunyavirus,and risk its transmission,in order to provide background data theoretical basis prevention fever with thrombocytopenia syndromes Beijing.Methods Examine rodents‘and canines'blood sera gained five suburb counties 2010...
Electrocardiogram (ECG) has been more and widely used over the past several decades. However, commonly ECG instrument disadvantages of large area occupation heavy. Due to strong sudden nature heart disease, traditional electrocardiotic monitoring system cumbersome operation poor real-time electrocardiograms. Ordinary people cannot read electrocardiogram correctly, meet needs individual family electrocardiological supervision at any time anywhere. Patients often lose valuable rescue even...
In this article, we conducted: I Study on comparisons of serological activity between phenolic glycolipid (PG I) and its terminal sugar which was a synthetic antigen conjugated to bovine gamma globulin.The sera for comparison were collected from leprosy patients (182 cases), tuberculosis (20 normal persons (108 cases, in non endemic area leprosy).The results indicated that there highly significant positive correlation (correlation coefficient, r=O.72 p<0.0005) PGI M-BGG (monosaccharide...
The aim of this study was to evaluate the impact and mechanism co-blocking costimulatory signals CD28-B7-CD40-CD40L during immune allograft rejection. Forty-eight recipient rabbits were prepared as a high-risk corneal model. After surgery, animals randomly divided into: control group, MR1 anti-B7 group (n=12, each group). Subconjunctival injection first performed on surgery day until post-surgery five. Four weeks later, or when rejection occurred, cornea sampled detect analyze gene spectrum....