Hongliang Wang

ORCID: 0000-0002-3304-2683
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research
  • Viral gastroenteritis research and epidemiology
  • MicroRNA in disease regulation
  • Influenza Virus Research Studies
  • Bacteriophages and microbial interactions
  • Hepatitis C virus research
  • Biosensors and Analytical Detection
  • COVID-19 Clinical Research Studies
  • Cellular transport and secretion
  • Multiferroics and related materials
  • Ferroelectric and Piezoelectric Materials
  • Bacterial Genetics and Biotechnology
  • Plant Molecular Biology Research
  • SARS-CoV-2 detection and testing
  • HIV Research and Treatment
  • Kidney Stones and Urolithiasis Treatments
  • Pediatric Urology and Nephrology Studies
  • Advanced biosensing and bioanalysis techniques
  • Endoplasmic Reticulum Stress and Disease
  • Phagocytosis and Immune Regulation
  • Sulfur Compounds in Biology
  • Monoclonal and Polyclonal Antibodies Research

Xinzhou Teachers University
2021-2025

Chinese Center For Disease Control and Prevention
2023-2025

National Health and Family Planning Commission
2025

First Affiliated Hospital of Xi'an Jiaotong University
2019-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2024

Xi'an Jiaotong University
2019-2024

Tsinghua University
2012-2024

State Key Laboratory of New Ceramics and Fine Processing
2022-2024

Harbin Engineering University
2014-2024

National Marine Environmental Forecasting Center
2024

Polyurethane foam (PUF) is the most widely used polymeric foam, owing to its low cost, minimal density, and superior thermal insulation characteristics. Nonetheless, applications are constrained by suboptimal acoustics fire performance coupled with safety concerns. This study introduces phosphorus-containing graphene oxide (D-GO)─a derivative of (GO)─that designed modified enhance PUF considerably. The D-GO composited (D-GO/PUF) was synthesized employing vacuum impregnation technology....

10.1021/acsapm.3c02706 article EN ACS Applied Polymer Materials 2024-01-26

Abstract The creation of functional hydrogels with robust load‐bearing capacity adaptable to complex tissue regeneration remains challenging. Silk fibroin (SF) is a natural biomaterial excellent mechanical strength and cell adhesion capacity, possessing tremendous potential solve the aforementioned dilemma. biodegradability biocompatibility molecular structure multiple modifiable moieties provide opportunities for injectability multifunctionality hydrogels. Furthermore, incorporation other...

10.1002/adfm.202405255 article EN Advanced Functional Materials 2024-07-21

Purpose: The aims of this study were to explore the differences in total body water and hydration status among Chinese children aged 6–17 years. Methods: A cross-sectional was implemented years China. (TBW), intracellular (ICW), extracellular (ECW) determined by bioelectrical impedance analysis (BIA). participants divided according age—age 6–8 years, age 9–11 12–14 15–17 years—and mass index (BMI) China—underweight, normal weight, overweight, obese groups. variables groups compared using...

10.3390/nu17020364 article EN Nutrients 2025-01-20

Hepatitis C virus (HCV) is a single-stranded RNA that replicates on endoplasmic reticulum-derived membranes. HCV particle assembly dependent the association of core protein with cellular lipid droplets (LDs). However, it remains uncertain whether occurs at LD membrane itself or closely associated ER Furthermore, not known how replication complex and progeny genomes physically associate presumed sites virion near LDs. Using an unbiased proteomic strategy, we have found Rab18 interacts...

10.1371/journal.ppat.1003513 article EN cc-by PLoS Pathogens 2013-08-01

Plant organs, such as seeds, are primary sources of food for both humans and animals. Seed size is one the major agronomic traits that have been selected in crop plants during their domestication. Legume seeds a source dietary proteins oils. Here, we report conserved role BIG SEEDS1 (BS1) gene control seed weight model legume Medicago truncatula grain soybean (Glycine max). BS1 encodes plant-specific transcription regulator plays key plant including pods, leaves, through regulatory module...

10.1073/pnas.1611763113 article EN Proceedings of the National Academy of Sciences 2016-10-17

In response to the recognized need for high throughput biodosimetry methods use after large-scale radiological events, a logical approach is complete automation of standard biodosimetric assays that are currently performed manually. The authors describe progress date on RABIT (Rapid Automated BIodosimetry Tool), designed score micronuclei or γ-H2AX fluorescence in lymphocytes derived from single drop blood fingerstick. system be completely automated, input capillary sample into machine...

10.1097/hp.0b013e3181ab3cb6 article EN Health Physics 2010-01-06

Plant leaves are diverse in their morphology, reflecting to a large degree the plant diversity natural environment. How different leaf morphology is determined not yet understood. The leguminous Medicago truncatula exhibits dissected with three leaflets at tip. We show that development of trifoliate by Cys(2)His(2) zinc finger transcription factor PALM1. Loss-of-function mutants PALM1 develop five clustered demonstrate binds specific promoter sequence and down-regulates expression M. LEAFY /...

10.1073/pnas.1003954107 article EN Proceedings of the National Academy of Sciences 2010-05-24

Abstract Coronavirus disease 2019 (COVID-19) includes the cardiovascular complications in addition to respiratory disease. SARS-CoV-2 infection impairs endothelial function and induces vascular inflammation, leading endotheliitis. relies on binding of Spike glycoprotein (S protein) angiotensin converting enzyme 2 (ACE2) host cells. We show here that S protein alone can damage cells (ECs) vitro vivo, manifested by impaired mitochondrial function, decreased ACE2 expression eNOS activity,...

10.1101/2020.12.04.409144 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-12-04

Dietary shifts in populations undergoing rapid economic transitions have been proposed as partly contributing toward the intergenerational rise myopia prevalence; however, empirical evidence of effect dietary factors on is limited. This study investigated association between and incident Chinese children aged 10-11 years. We evaluated habits using a 72-item food frequency questionnaire (FFQ) among 7423 children. Myopic status was assessed "General Personal Information Questionnaire"....

10.3390/nu15081946 article EN Nutrients 2023-04-18

As a prominent characteristic of cell life, the regulation quiescence is important for proper development, regeneration, and stress resistance may play role in certain degenerative diseases. However, mechanism underlying remains largely unknown. Encysted embryos Artemia are useful studying this state because they remain quiescent prolonged periods during diapause, obligate dormancy. In present study, SET domain-containing protein 4, histone lysine methyltransferase from Artemia, was...

10.1128/mcb.00453-16 article EN Molecular and Cellular Biology 2016-12-29

Given the serious neurological complications and deaths associated with enterovirus 71 (EV71) infection, there is an urgent need to develop effective antivirals against this viral infection. In study, we demonstrated that two Cathelicidin-derived peptides, LL-18 FF-18 were more potent EV71 infection than parent peptide LL-37, which mature processed form of Cathelicidin. These peptides could directly bind virus particles, but not coxsackievirus, indicative their high specificity. The binding...

10.1371/journal.ppat.1011967 article EN cc-by PLoS Pathogens 2024-01-25

We developed a capillary-based centrifugal indicator (CBCI) equipped with in situ bacteria culture for fast AST. The CBCI realized the combination of macro bacterial incubation and early micro assessment.

10.1039/d3an02144k article EN The Analyst 2024-01-01

Background/Objectives: The prevalence of both myopia and obesity is increasing among children adolescents around the world. We aimed to examine association between weight status in Chinese adolescents. Methods: analysis included 35,108 participants aged 6–17 from a nationwide cross-sectional survey. Results: Our results indicated that girls with overweight had higher odds ratio (OR) mild myopia: ages 6–8 (OR = 1.33, 95% CI: 1.01–1.76; OR 1.71, 1.14–2.55) 9–11 1.22, 1.03–1.44; 1.31,...

10.3390/nu17020260 article EN Nutrients 2025-01-12

<title>Abstract</title> Hydrogen sulfide (H<sub>2</sub>S) is recognized as a critical gas signal molecule in the development and treatment of various diseases. Therefore, potent fluorescent probe for detection H<sub>2</sub>S great significance biological systems. Herein, we synthesis new probe, 3-(benzo[d]thiazol-2-yl)-2-(2,4-dinitrophenoxy)-5-methylbenzaldehyde (<bold>DPM-H</bold><sub><bold>2</bold></sub><bold>S</bold>) to detect based on recognition strategy that uses an ortho-aldehyde...

10.21203/rs.3.rs-5871966/v1 preprint EN cc-by Research Square (Research Square) 2025-01-23
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