A5041808631- Attention Deficit Hyperactivity Disorder
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Autism Spectrum Disorder Research
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Children's Physical and Motor Development
- Genetics and Neurodevelopmental Disorders
- Neurotransmitter Receptor Influence on Behavior
- Behavioral and Psychological Studies
- Hemispheric Asymmetry in Neuroscience
- Pharmaceutical studies and practices
- EEG and Brain-Computer Interfaces
- Adolescent and Pediatric Healthcare
- Obsessive-Compulsive Spectrum Disorders
- Genetic Associations and Epidemiology
- Vagus Nerve Stimulation Research
- Neurological disorders and treatments
- Child Nutrition and Feeding Issues
- Infant Development and Preterm Care
- Treatment of Major Depression
- Prenatal Substance Exposure Effects
- Health Systems, Economic Evaluations, Quality of Life
- Health, Environment, Cognitive Aging
- Childhood Cancer Survivors' Quality of Life
University of California, Los Angeles
2013-2024
Gomel Engineering Institute
2018
Salk Institute for Biological Studies
2018
Neurobehavioral Systems
2000-2014
UCLA Medical Center
2002-2014
Cardiff University
2013
Radboud University Nijmegen
2013
Takeda (United States)
2005-2012
Stone Clinic
2012
University Hospitals Cleveland Medical Center
2012
Atypical antipsychotic agents, which block postsynaptic dopamine and serotonin receptors, have advantages over traditional medications in the treatment of adults with schizophrenia may be beneficial children autistic disorder who serious behavioral disturbances. However, data on safety efficacy atypical agents are limited.
OBJECTIVE: Risperidone has been found efficacious for decreasing severe tantrums, aggression, and self-injurious behavior in children adolescents with autistic disorder (autism). The authors report on whether risperidone improves the core symptoms of autism, social communication impairment repetitive stereotyped behavior. METHOD: database from an 8-week double-blind, placebo-controlled trial (N=101) 16-week open-label continuation study (N=63) autism was used to test drug effects secondary...
OBJECTIVE: Patterns of psychiatric comorbidity were assessed in adults with and without attention deficit hyperactivity disorder (ADHD) identified through a genetic study families containing multiple children ADHD. METHOD: Lifetime ADHD comorbid psychopathology 435 parents Rates mean ages at onset compared lifetime ADHD, persistent those Age-adjusted rates Kaplan-Meier survival curves. Logistic regression was used to assess additional risk factors for conditions more frequent subjects....
Objective: Short-term, controlled studies of extended-release guanfacine (GXR), a selective α2A-adrenoreceptor agonist, demonstrate efficacy in treating attention-deficit/hyperactivity disorder (ADHD) symptoms as monotherapy. This 2-year open-label study was conducted to further assess the long-term safety and GXR. Methods: Study participants, aged 6–17 years with ADHD, had previously been exposed GXR therapy alone or combination psychostimulants one two antecedent trials. In this study,...
Objective: The aim of this study was to describe the clinical presentation preschoolers diagnosed with moderate severe attention-deficit/hyperactivity disorder (ADHD) recruited for multisite Preschool ADHD Treatment Study (PATS). diagnosis and evaluation process will also be described. Method: A comprehensive multidimensional, multi-informant assessment protocol implemented including semistructured PATS Diagnostic Interview. Parent- teacher-report measures were used supplement information...
In the current study we sought to dissociate component processes of working memory (WM) (vigilance, encoding and maintenance) that may be differentially impaired in attention-deficit/ hyperactivity disorder (ADHD). We collected electroencephalographic (EEG) data from 52 children with ADHD 47 typically developing (TD) children, ages 7-14 years, while they performed a spatial Sternberg task. used independent analysis time-frequency identify midoccipital alpha (8-12 Hz) evaluate frontal midline...
OBJECTIVE Although attention deficit hyperactivity disorder (ADHD) is highly heritable, genome-wide association studies (GWAS) have not yet identified any common genetic variants that contribute to risk. There evidence aggression or conduct in children with ADHD indexes higher loading and clinical severity. The authors examine whether considered en masse as polygenic scores for are especially enriched comorbid disorder. METHOD Polygenic derived from an GWAS meta-analysis were calculated...