Bru Cormand
- Attention Deficit Hyperactivity Disorder
- Genetics and Neurodevelopmental Disorders
- Migraine and Headache Studies
- Autism Spectrum Disorder Research
- Neurotransmitter Receptor Influence on Behavior
- Genetic Associations and Epidemiology
- Lysosomal Storage Disorders Research
- Bipolar Disorder and Treatment
- Cellular transport and secretion
- Functional Brain Connectivity Studies
- Metabolism and Genetic Disorders
- Neuroscience of respiration and sleep
- Genetic Neurodegenerative Diseases
- Receptor Mechanisms and Signaling
- Congenital heart defects research
- Glycosylation and Glycoproteins Research
- Carbohydrate Chemistry and Synthesis
- Zebrafish Biomedical Research Applications
- Mitochondrial Function and Pathology
- Epigenetics and DNA Methylation
- Genomics and Rare Diseases
- Genomic variations and chromosomal abnormalities
- Substance Abuse Treatment and Outcomes
- Neuroendocrine regulation and behavior
- Amino Acid Enzymes and Metabolism
Universitat de Barcelona
2016-2025
Institut de Biomedicina de la Universitat de Barcelona
2015-2024
Centro de Investigación Biomédica en Red
2015-2024
Centre for Biomedical Network Research on Rare Diseases
2015-2024
Sant Joan de Déu Research Foundation
2016-2024
Institut de Recerca Sant Joan de Déu
2016-2024
Instituto de Investigación de Enfermedades Raras
2014-2024
Instituto de Salud Carlos III
2014-2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2022
Institut de Recherche pour le Développement
2021
Inherited variation contributes to autism About one-quarter of genetic variants that are associated with spectrum disorder (ASD) due de novo mutations in protein-coding genes. Brandler et al. wanted determine whether changes noncoding regions the genome autism. They applied whole-genome sequencing ∼2600 families at least one affected child. Children ASD had inherited structural from their father. Regulatory some specific genes were disrupted among multiple families, supporting idea a...
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of school-age children and 2.5% adults. Common genetic variants contribute substantially to ADHD susceptibility, but no individual have been robustly associated with ADHD. We report genome-wide association meta-analysis 20,183 cases 35,191 controls that identifies surpassing significance in 12 independent loci, revealing new important information on the underlying biology...
BackgroundAttention-deficit/hyperactivity disorder (ADHD) shows substantial heritability and is two to seven times more common in male individuals than female individuals. We examined putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity higher burden of risk cases.MethodsWe analyzed genome-wide autosomal variants from the Psychiatric Genomics Consortium iPSYCH Project (n = 20,183 cases, n 35,191 controls) Swedish population register data 77,905 1,874,637...
Abstract Human genome-wide association studies (GWAS), transcriptome analyses of animal models, and candidate gene have advanced our understanding the genetic architecture aggressive behaviors. However, each these methods presents unique limitations. To generate a more confident comprehensive view complex genetics underlying aggression, we undertook an integrated, cross-species approach. We focused on human rodent models to derive eight lists from three main categories evidence: two sets...