A5014352191- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- HIV Research and Treatment
- Plant Reproductive Biology
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- Sex work and related issues
- HIV, TB, and STIs Epidemiology
- Plant nutrient uptake and metabolism
- Hepatitis B Virus Studies
- Probiotics and Fermented Foods
- Polysaccharides and Plant Cell Walls
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- HIV/AIDS Impact and Responses
- Hepatitis C virus research
- Cancer-related molecular mechanisms research
- Bacterial biofilms and quorum sensing
- Plant-Microbe Interactions and Immunity
- Photosynthetic Processes and Mechanisms
- Data-Driven Disease Surveillance
- Genetic Mapping and Diversity in Plants and Animals
- Plant responses to water stress
Guangxi Medical University
2024-2025
Chinese Center For Disease Control and Prevention
2009-2024
Anhui Agricultural University
2018-2024
Shanxi Provincial Children's Hospital
2024
Beijing Red Cross Blood Center
2024
Lanzhou University
2013-2023
Affiliated Hospital of Jining Medical University
2019-2023
University Medical Center of the Johannes Gutenberg University Mainz
2015-2019
Institute of Medical Microbiology and Hygiene
2016-2019
Johannes Gutenberg University Mainz
2015-2019
Objective: To present the methods used for 2007 estimates number of people at risk and infected with HIV. Design: Estimation work took place throughout 2007, led by National Center AIDS Sexually Transmitted Disease Control Prevention in collaboration United Nations World Health Organization. Methods: The workbook method was to process prefecture county-level surveillance data generate HIV prevalence group each prefecture, which turn imported into spectrum model new infections HIV-related...
This study aimed to investigate how Akkermansia muciniphila can implicate type 2 diabetes mellitus and the mechanisms underlying effects A. on mellitus. Normal streptozotocin-induced diabetic Sprague-Dawley rats were orally administered with solvent. After 4 weeks of treatment, live or pasteurized exhibited significant increase in blood concentration high-density lipoprotein, decrease hepatic glycogen, serum plasminogen activator inhibitor-1, tumor necrosis factor-α, lipopolysaccharide,...
Gibberellins (GAs) are a class of important phytohormones regulating variety physiological processes during normal plant growth and development. One the major events GA-mediated is degradation DELLA proteins, key negative regulators GA signaling pathway. The stability proteins thought to be controlled by protein phosphorylation dephosphorylation. Up date, no phosphatase involved in this process has been identified. We have identified dwarfed dominant-negative Arabidopsis mutant, named...
Background. Recent studies have indicated an increasing burden of human immunodeficiency virus (HIV)/AIDS among older adults.
Clinical trials have demonstrated that immediate initiation of antiretroviral therapy (ART) reduces AIDS-related morbidity and mortality. We tested the hypothesis initiating ART ≤30 days after human immunodeficiency virus (HIV) diagnosis would be associated with reduced mortality among people living HIV (PLWH) CD4 counts >500 cells/μL.PLWH enrolled in Chinese National Information System between January 2012 June 2014 cells/μL were followed for 12 months. Cox proportional hazards model was...
Studies have shown a recent upsurge in human immunodeficiency virus (HIV) burden among men who sex with (MSM) China, especially urban areas. For intervention planning and resource allocation, spatial analyses of HIV/AIDS case-clusters were required to identify epidemic foci trends MSM China. Information regarding recorded as cases during 2006–2015 extracted from the National Case Reporting System. Demographic determined through Cochran-Armitage trend tests. Distribution was examined using...
Abstract Dearth of information regarding the trend and correlates HIV, syphilis Hepatitis C (HCV) in a country-wide sample understudied though high-risk Chinese men who have sex with (MSM) called for comprehensive serial cross-sectional study. Using multistage mixed-method strategy, 171,311 MSM from 107 selected cities/counties 30 provinces mainland China, were interviewed tested. Descriptive, bivariate, multivariate Cochran-Armitage analyses conducted using SAS 9.2. During 2009-13, recent...
Abstract In plants, cell morphogenesis is dependent on intercellular auxin accumulation. The polar subcellular localization of the PIN-FORMED (PIN) protein crucial for this process. Previous studies have shown that kinase PINOID (PID) and phosphatase6-type phosphatase holoenzyme regulate phosphorylation status PIN1 in root tips shoot apices. Here, we show a type-one phosphatase, TOPP4, essential formation interdigitated pavement (PC) pattern Arabidopsis (Arabidopsis thaliana) leaf....
Abstract Background Heat shock transcription factors (Hsfs) are highly conserved among eukaryote and always play vital role in plant stress responses. Whereas, function mechanism of Hsfs maize limited. Results In this study, an HSF gene ZmHsf11 , a member class B Hsfs, was cloned from maize, it up-regulated under heat treatment. nuclear protein with no transcriptional autoactivation activity yeast. Overexpression Arabidopsis rice significantly reduced the survival rate treatment decreased...
Cancer stem cells (CSCs) are considered tumor-initiating and the main drivers of disease progression. Targeting these rare cancer cells, however, remains challenging with respect to therapeutic benefit. Here, we report up-regulation IL-13RA2 expression in colorectal (CRC) tissues spheroid cells. The was positively correlated canonical stemness markers CRC. We further demonstrated that level IL-13 up-regulated serum CRC patients. Biologically, recombinant (rIL-13) stimulation promoted sphere...
Abstract Introduction The dynamic HIV/AIDS epidemic significantly impacts China, particularly affecting injection drug users (IDUs), former plasma donors (FPDs), men who have sex with (MSM), and those engaging in high-risk heterosexual behavior (HRHB). This study specifically focuses on identifying the risk factors influences that drive spread of HIV among these population groups by performing a comprehensive analysis contact histories individuals diagnosed HIV. Methods Data for this...
Abstract Background COVID-19-induced acute respiratory distress syndrome (ARDS) can result in tissue damage and multiple organ dysfunction, especially kidney transplant recipients (KTRs) receiving immunosuppressive drugs. Presently, single-cell research on ARDS is considerably advanced, yet knowledge about KTRs still constrained. Methods Single-cell RNA sequencing (scRNA-seq) analysis was performed to construct a comprehensive immune landscape of the peripheral blood mononuclear cells...
The growth and development of maize (Zea mays L.) are significantly impeded by prolonged exposure to high temperatures. Heat stress transcription factors (HSFs) play crucial roles in enabling plants detect respond elevated However, the genetic mechanisms underlying responses HSFs heat remain unclear. Thus, we aimed investigate role ZmHSFA2B regulating tolerance maize. Here, report that has two splicing variants, ZmHSFA2B-I ZmHSFA2B-II. encodes full-length (ZmHSFA2B-I), whereas ZmHSFA2B-II a...
This study aimed to analyze the epidemiological characteristics and clinical symptoms of mpox cases with without human immunodeficiency virus (HIV) reported in China 2023, providing evidence for coordinated prevention control strategies both infections. All confirmed 2023 were extracted from China's Information System Disease Control Prevention. Data collected surveillance system investigations. Statistical analyses performed using SPSS 24.0, group comparisons conducted t-tests chi-square...
Summary Hepatitis C virus now represents a global viral pandemic and is the fourth most commonly reported infectious disease in China. Information on China's national HCV epidemic was limited to cross ‐sectional seroprevalence studies of special populations, surveillance effort had been launched inform prevention control. We analysed novel data from two databases: (i) medical case report system (ii) sentinel system. Between 1997 2012, reporting incidence cases for infection rose 0.7 15.0 per...
To determine policy implications, this analysis tracks the evolution of HIV/AIDS infection across China to understand current trends and potential risk factors.A retrospective study with spatial analytical model multilevel models was conducted among 326,157 cases reported from 1989-2009. The results indicate that distribution clustered at county level different directional distributions 2003 2009. Compared 2003, by 2009 there a 122% increase in HIV rural residents, 294% urban 211% migrants,...
Late diagnosis of HIV infection is common. We aim to assess the proportion newly diagnosed cases receiving timely baseline CD4 count testing and associated factors in China.Data were extracted from Chinese HIV/AIDS Comprehensive Response Information Management System. Adult patients over 15 years old who had been with China between 2006 2012 identified. The study cohort comprised individuals a measured count.Among 388,496 identified cases, median was 294 cells/µl (IQR: 130-454), half (N =...