A5101474911- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Diabetes Treatment and Management
- Virus-based gene therapy research
- Herpesvirus Infections and Treatments
- Medicinal Plant Pharmacodynamics Research
- Cytomegalovirus and herpesvirus research
- Diabetes Management and Research
- Cancer-related molecular mechanisms research
- Immune Response and Inflammation
- Escherichia coli research studies
- Andrographolide Research and Applications
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Immune Cell Function and Interaction
- Plant-based Medicinal Research
- Traditional Chinese Medicine Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Healthcare and Venom Research
- Yersinia bacterium, plague, ectoparasites research
- Metabolism, Diabetes, and Cancer
- Microbial infections and disease research
- Pancreatic function and diabetes
- Heart Failure Treatment and Management
- Salmonella and Campylobacter epidemiology
Kunming Medical University
2020-2021
Weatherford College
2021
Zhejiang Sci-Tech University
2006-2020
Institute of Cardiology
2020
Hubei Cancer Hospital
2015-2019
Jilin University
2006-2016
Zhejiang University
2014-2015
Animal Science Research Institute
2012
Jilin Medical University
2012
Sichuan Agricultural University
2012
Xiang-Qi-Tang (XQT) is a Chinese herbal formula containing Cyperus rotundus, Astragalus membranaceus and Andrographis paniculata. Alpha-Cyperone (CYP), astragaloside IV (AS-IV) andrographolide (AND) are the three major active components in this formula. XQT may modulate inflammatory or coagulant responses. We therefore assessed effects of on lipopolysaccharide (LPS)-induced model rat cardiac microvascular endothelial cells (RCMECs). XQT, CYP, AS-IV AND inhibited production tumor necrosis...
AbstractBackground: Hepatocellular carcinoma (HCC) is one of the most difficult tumors to be treated. Overexpression human telomerase reverse transcriptase (hTERT) and dysfunction retinoblastoma (RB) have been implicated in HCC. Oncolytic viruses used as targeting therapy for different malignancies. In study, we engineered oncolytic adenovirus target both TERT RB pathways achieve strict tumor specificity. Methods: A double-controlled recombinant (AdCN103) was constructed by deletion 24bp CR2...
Context: Ginsenoside Rh2, an active component of ginseng, exhibits immunoregulatory and anti-inflammatory properties. Rh2-B1, a sulfated derivative, was prepared to enhance its water solubility. We studied the effect Rh2-B1 on CTLL-2, CD8+ cytotoxic T cell line that known for protecting against viral infection.Objective: aimed investigate interferon (IFN)-γ production proliferation possible mechanism.Materials methods: Enzyme-linked immunosorbent assay (ELISA) employed analyze IFN-γ...
The impact of reduction systolic blood pressure or body weight on cardiovascular events during the treatment with glucagon-like peptide 1 receptor agonists (GLP-1RAs) sodium-glucose cotransporter 2 inhibitors (SGLT2is) for type diabetes is unclear. We searched Embase and PubMed. performed meta-analysis using hazard ratio (HR) 95% confidence interval (CI) as effect size stratified by drug class six endpoints interest, which were major adverse (MACE), hospitalization heart failure (HHF), death...
Xiang-qi-tang (XQT) is a Chinese herbal formula containing rhizoma Cyperi, Andrographis paniculata and Astragalus membranaceus. The present study investigated the effects of XQT on mortality inflammatory mediators in chicken model challenged with avian pathogenic Escherichia coli (APEC). To detect effect XQT, chickens were pretreated 12 h before being 10(8) colony forming unit (CFU) APEC. results showed that 0.6 g/kg significantly elevated survival rate infected chickens. further investigate...
Lin et al. recently did a network meta-analysis based on cardiovascular (CV) outcome trials (CVOTs) of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and those glucagon-like peptide-1 receptor agonists (GLP1RAs). Due to the absence CVOTs directly comparing SGLT2is with GLP1RAs, al.'s identified indirect evidence that vs. GLP1RAs reduced hospitalization for heart failure (HHF) but not reduce CV death all-cause mortality (ACM) in patients type diabetes (T2D). We another incorporating...