A5008364172- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Helminth infection and control
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Cardiovascular Issues in Pregnancy
- Circadian rhythm and melatonin
- Coenzyme Q10 studies and effects
- SARS-CoV-2 and COVID-19 Research
- Insect symbiosis and bacterial influences
- Psychodrama and Leishmaniasis Studies
- Neurotransmitter Receptor Influence on Behavior
- vaccines and immunoinformatics approaches
- Bee Products Chemical Analysis
- Global Maternal and Child Health
- Coffee research and impacts
- Nicotinic Acetylcholine Receptors Study
- Bipolar Disorder and Treatment
- Chemical synthesis and alkaloids
- Garlic and Onion Studies
- Trace Elements in Health
- Insect Pest Control Strategies
- Pregnancy and Medication Impact
- Parasitic Infections and Diagnostics
- COVID-19 Clinical Research Studies
Universidade Federal do Oeste da Bahia
2020-2021
Universidade de São Paulo
2009-2014
Universitat de València
2014
Coordenação de Aperfeicoamento de Pessoal de Nível Superior
2013
Fundação de Amparo à Pesquisa do Estado de São Paulo
2009-2013
Financiadora de Estudos e Projetos
2009
Abstract Leishmaniasis is an infection caused by a protozoan parasite of the genus Leishmania and second most prevalent parasitic protozoal disease after malaria in world. We report vitro leishmanicidal activity on promastigote forms amazonensis cytotoxicity, using LLCMK 2 cells, glycoalkaloids from fruits Solanum lycocarpum , determined colorimetric methods. The alkaloidic extract was obtained acid‐base extraction; solamargine solasonine were isolated silica‐gel chromatography, followed...
The aim of this study was to evaluate a possible synergism between melatonin and meloxicam in up-regulating the immune response male Wistar rats infected with Trypanosoma cruzi during immunosuppression phenomenon, which characterizes acute phase Chagas' disease. Male were Y strain T. cruzi. Experiments performed on 7, 14 21 days post-infection. Several immunological parameters evaluated including gamma-interferon (IFN-gamma), interleukin-2 (IL-2), nitric oxide (NO) prostaglandin E(2)...
Abstract: Previous studies showed that melatonin or dehydroepiandrosterone (DHEA) enhances the immune response against parasitic pathogens. The present study investigated in vitro activity of combined with DHEA a period 24 hr during course vivo T. cruzi infection. alone, as well together, were tested for trypomastigote forms (doses ranging from 0.5 to 128 μ m ). In vitro, neither nor alone had any forms, although when highest concentration and was used, it active parasite. However, this...
Schistosomiasis is a chronic disease caused by trematode flatworms of the genus Schistosoma; it accounts for more than 280,000 deaths annually. In this work we investigated effect alkaloidic extract obtained acid-base extraction dried fruits Solanum lycocarpum on schistosomiasis. We used at concentrations 10, 20, and 40 mg/kg to treat mice infected with Schistosoma mansoni in different phases parasite cycle, compared its that positive control praziquantel (60 mg/kg). evaluated results basis...
Studies were made on the ribosomal DNA intergenic region, comprising complete internal transcribed spacer (ITS)-1, 5.8S, and ITS-2 sequences, of populations triatomine Panstrongylus megistus, most important vector Chagas' disease in Brazil since Triatoma infestans eradication. Specimens from 26 localities Rio Grande do Sul, Santa Catarina, Paraná, São Paulo, Minas Gerais, Bahia, Sergipe states. In total, 21 ITS-1 12 haplotypes found. Nucleotide differences higher (3.00%) than (1.33%). The...
SUMMARY Acute Chagas disease outbreaks are related to the consumption of food or drink contaminated by triatomine feces, thus making oral infection an important route transmission. Both vector-borne and infections trigger cardiac manifestations in host that a dysregulated immune response. The aims this work were evaluate possible alterations lymphocyte CD 4+ /CD 8+ sub-populations, Th1 Th2 cytokines, nitrite concentrations histopathology. One group male Wistar rats was intraperitoneally...