Manuel Döhla

ORCID: 0000-0001-8029-5264
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 detection and testing
  • Infection Control and Ventilation
  • SARS-CoV-2 and COVID-19 Research
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Medical Device Sterilization and Disinfection
  • Antibiotic Use and Resistance
  • Biosensors and Analytical Detection
  • Antibiotic Resistance in Bacteria
  • Gut microbiota and health
  • Infection Control in Healthcare
  • Gastroesophageal reflux and treatments
  • Pharmaceutical Quality and Counterfeiting
  • Eosinophilic Esophagitis
  • Disaster Response and Management
  • Biochemical Analysis and Sensing Techniques
  • COVID-19 Clinical Research Studies
  • Helicobacter pylori-related gastroenterology studies
  • Environmental and Social Impact Assessments
  • Recycling and Waste Management Techniques
  • Respiratory viral infections research
  • Olfactory and Sensory Function Studies
  • Advanced Chemical Sensor Technologies
  • Viral Infections and Outbreaks Research
  • Advanced biosensing and bioanalysis techniques
  • Urinary Tract Infections Management

Bundeswehrzentralkrankenhaus Koblenz
2021-2025

University of Bonn
2020-2025

Heinrich Heine University Düsseldorf
2024

Düsseldorf University Hospital
2024

University Hospital Bonn
2019-2024

Institut für Hygiene und Umwelt
2021

Leipzig University
2021

Faculty (United Kingdom)
2020

Bayreuth Medical Center
2018

Abstract The role of environmental transmission SARS-CoV-2 remains unclear. Particularly the close contact persons living together or cohabitating in domestic quarantine could result high risk for exposure to virus within households. Therefore, aim this study was investigate whereabouts and whether useful precautions prevent dissemination can be given. 21 households under conditions were randomly selected study. All each household recorded terms age, sex time quarantine. Throat swabs...

10.1101/2020.05.28.20114041 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-06-02

Frequent testing of large population groups combined with contact tracing and isolation measures will be crucial for containing Coronavirus Disease 2019 outbreaks. Here we present LAMP-Seq, a modified, highly scalable reverse transcription loop-mediated isothermal amplification (RT-LAMP) method. Unpurified biosamples are barcoded amplified in single heat step, pooled products analyzed en masse by sequencing. Using commercial reagents, LAMP-Seq has limit detection ~2.2 molecules per µl at 95%...

10.1038/s41587-021-00966-9 article EN other-oa Nature Biotechnology 2021-06-29

The role of environmental transmission SARS-CoV-2 remains unclear. Thus, the aim this study was to investigate whether viral contamination air, wastewater, and surfaces in quarantined households result a higher risk for exposed persons. For study, source population 21 under quarantine conditions with at least one person who tested positive RNA were randomly selected from community North Rhine-Westphalia March 2020. All individuals living these participated provided throat swabs analysis. Air...

10.3390/v14051075 article EN cc-by Viruses 2022-05-17

Antimicrobial resistance is a global threat to safe health care, and reduction in antibiotic consumption seems be an appropriate preventive measure. In Germany, the reporting of hospital antibiotics independent institution only voluntary. Although high level willingness improve can assumed case participation, median consumptions hospitals change slightly. This study examines question whether logistical figures adequately reflect real consumption, if not, how optimize use data for clinical...

10.3390/antibiotics14010043 article EN cc-by Antibiotics 2025-01-06

Background: Staphylococcus aureus bacteremia (SAB) is of great clinical relevance, as it the most common type bacteremia. Several studies show that quality care and thus outcome can be positively influenced by involvement infectious disease specialists structured programs like Antimicrobial Stewardship (AMS). In 2020, SARS-CoV-2 pandemic occurred, which dominated healthcare system global events during this time. At same time, a standard operational procedure (SOP) for SAB management (SABQM)...

10.3390/diseases13040104 article EN cc-by Diseases 2025-03-30

Abstract The effect of filtering face piece grade 2 (FFP2) masks for infection prevention is essential in health care systems; however, it depends on supply chains. Efficient methods to reprocess FFP2 may be needed disasters. Therefore, different UV-C irradiation schemes bacterial decontamination used were investigated. Seventy-eight irradiated with UV light durations between 3 and 120 seconds subsequently analyzed the presence viable bacteria inside. Ten served as control group. Irradiation...

10.1017/dmp.2024.86 article EN Disaster Medicine and Public Health Preparedness 2024-01-01

SARS-CoV-2 infection has been characterized as an upper and lower respiratory tract with symptoms ranging from sore throat, cough, headache, fatigue to a severe syndrome that requires intensive care [1-7]. Although death rate recorded for in comparison other recent coronavirus outbreaks, such MERS or SARS, compromised status on admission associated fatal outcomes. Among the >1200 SARS-CoV-2-infected individuals Germany date, many of diagnosed persons show mild no clinical signs infection....

10.20411/pai.v5i1.374 article EN cc-by Pathogens and Immunity 2020-05-16

Indoor spaces exhibit microbial compositions that are distinctly dissimilar from one another and outdoor spaces. Unique in this regard, a topic has only recently come into focus, is the microbiome of hospitals. While benefits knowing exactly which microorganisms propagate how where hospitals undoubtedly beneficial for preventing hospital-acquired infections, there are, to date, no standardized procedures on best study hospital microbiome. Our aimed investigate sanitary facilities, outlining...

10.3390/microorganisms11010185 article EN cc-by Microorganisms 2023-01-11

We investigated a COVID-19 outbreak with the first case of hitherto rare viral variant B.1.640.2 possible Cameroonian origin in high school Germany December 2021.

10.1055/s-0044-1781946 article EN Das Gesundheitswesen 2024-04-01

Lead pipes have been used in drinking water installations for a long time. Only since 1973 their use new buildings strongly discouraged; nevertheless, they are still found old buildings. Furthermore, lead-containing alloys today components such as fittings. This results an avoidable pollution of water. The health significance this is acknowledged by reduction the currently valid limit value from 10 µg/l to 5 EU directive passed 2020. provides transition period 15 years.The relevance stricter...

10.1007/s00103-021-03292-2 article DE cc-by Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2021-02-26
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