A5101821072- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Trigeminal Neuralgia and Treatments
- Neural and Behavioral Psychology Studies
- Aortic Disease and Treatment Approaches
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- MicroRNA in disease regulation
- Infectious Aortic and Vascular Conditions
- Aortic aneurysm repair treatments
- EEG and Brain-Computer Interfaces
- Neurofibromatosis and Schwannoma Cases
- Traumatic Brain Injury Research
- Facial Nerve Paralysis Treatment and Research
- Circular RNAs in diseases
- Epilepsy research and treatment
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Neonatal and fetal brain pathology
- Head and Neck Surgical Oncology
- Pituitary Gland Disorders and Treatments
- Impact of Technology on Adolescents
- Cancer-related molecular mechanisms research
- Tissue Engineering and Regenerative Medicine
Second Xiangya Hospital of Central South University
2016-2024
Central South University
2015-2024
Anhui Provincial Hospital
2013-2022
University of Science and Technology of China
2018-2022
Shandong University
2018-2021
Xiangya Hospital Central South University
2016-2020
Anhui Medical University
2011-2020
Creative Commons
2018
Miami Children's Hospital
2018
Nagoya University
2010-2016
Increasing neuroimaging evidence suggests an association between impulsive decision-making behavior and task-related brain activity. However, the relationship impulsivity in resting-state activity remains unknown. To address this issue, we used functional MRI to record from human adults during a resting state delay discounting task (DDT) that requires choosing immediate smaller reward larger delayed reward. In experiment I, identified four DDT-related networks. The money network (the...
Background The default mode network (DMN) is a set of brain regions that exhibit synchronized low frequency oscillations at resting-state, and believed to be relevant attention self-monitoring. As the anterior cingulate cortex hippocampus are impaired in drug addiction meanwhile parts DMN, present study examined addiction-related alteration functional connectivity DMN. Methodology Resting-state magnetic resonance imaging data chronic heroin users (14 males, age: 30.1±5.3 years, range from 22...
Introduction : Excessive Internet use (EIU), also described as addiction or pathological use, has already become a serious social problem around the world. Some researchers consider EIU kind of behavioral addiction. However, there are few experimental studies on cognitive functions excessive users (EIUers) and limited data available to compare with other addictive behaviors, such drug abuse gambling. Methods In this study, we examined EIUers' decision-making prepotent response inhibition....
Mesenchymal stem cells (MSCs) are known to be capable of suppressing inflammatory responses. We previously reported that intra-abdominal implantation bone marrow-derived MSCs (BM-MSCs) sheet by laparotomy attenuated angiotensin II (AngII)-induced aortic aneurysm (AA) growth in apolipoprotein E-deficient (apoE-/-) mice through anti-inflammation effects. However, cell delivery is invasive; we here demonstrated the effects multiple intravenous administrations BM-MSCs on AngII-induced AA...
Abstract Abdominal Aortic aneurysm (AAA) is associated with chronic inflammation, cells apoptosis, and impairment of autophagy. BP-1-102, a novel potent STAT3 inhibitor, has been recently reported to significantly block inflammation-related signaling pathways JAK2/STAT3 NF-κB, as well regulate However, its role in vascular inflammation AAA progression remains be elucidated. In the present study, effect potential mechanisms BP-1-102 on angiotensin II (AngII) induced ApoE −/− mice were...
Abstract Purpose Previous researches have reported gray and white matter microalterations in primary trigeminal neuralgia (TN) with neurovascular compression (NVC). The central mechanism underlying TN without NVC are unknown but may include changes specific brain regions or circuitries. This study aimed to investigate abnormalities the (GM) (WM) of whole possible pathogenetic this disease. Methods We analyzed morphologic images patients, 23 (TN wNVC) 22 compared 45 healthy controls (HC). All...
An aortic aneurysm (AA) is caused by atherosclerosis with chronic inflammation. Mesenchymal stem cells (MSCs) have potential anti-inflammatory properties. In this study, we examined whether an already-formed AA can be treated intravenous injection of bone marrow-derived (BM)-MSCs in a mouse model. was induced apolipoprotein E-deficient mice angiotensin II-infusion for 28 days through sub-cutaneous osmotic mini-pumps. After that, 1 × 106 BM-MSCs (in 0.2 ml saline) or saline as control...
Summary Objective China has the largest population of patients with epilepsy worldwide, which imposes a heavy burden on public and health care systems. Several epidemiological surveys have been performed in China. Although these grossly describe prevalence gap treatment epilepsy, status centers is unclear. The number increased substantially recent decades. Therefore, nationwide investigation scale distribution, personnel, equipment, capacity each center great value. Methods In 2017–2018,...
Abstract Mesenchymal stem cells (MSCs) exhibit therapeutic benefits on aortic aneurysm (AA); however, the molecular mechanisms are not fully understood. The current study aimed to investigate effects and potential of murine bone marrow MSC (BM‐MSCs)–derived conditioned medium (MSCs‐CM) angiotensin II (AngII)‐induced AA in apolipoprotein E‐deficient (apoE −/− ) mice. Murine BM‐MSCs, MSCs‐CM or control were intravenously administrated into AngII‐induced apoE Mice sacrificed at 2 weeks after...
Molecular signaling of cardiac autonomic innervation is an unresolved issue. Here, we show that glial cell line-derived neurotrophic factor (GDNF) promotes sympathetic in vitro and vivo. In vitro, ventricular myocytes (VMs) neurons (SNs) isolated from neonatal rat ventricles superior cervical ganglia were cultured at a close distance. Then, morphological functional coupling between SNs VMs was assessed response to GDNF (10 ng/ml) or nerve growth (50 ng/ml). As result, fractions...
Migraine sufferers have abnormal cerebral information processing and personality disorders, post-traumatic headache also some changes. We therefore, studied intensity dependence of auditory evoked potentials, Plutchik-van Praag's depression inventory, Zuckerman's sensation seeking scales Zuckerman-Kuhlman's questionnaire in patients suffering from migraine without aura (n = 26) chronic headaches as well healthy volunteers 30). The group showed significantly increased neuroticism-anxiety than...
Primary objective: The aim of the present study was to investigate event-based prospective memory (EBPM) and time-based (TBPM) in patients with lesion prefrontal cortex (PFC) test hypothesis that is involved (PM) network.Research design: performance PFC (n= 30) compared a demographically matched control group 30).Methods procedures: A neuropsychological battery tests including EBPM TBPM tasks were administered both groups.Main outcome results: significantly impaired EBPM, but insignificantly...
Objective The effects of microRNAs (miRNAs) have been identified in epilepsy (Ep) recent years, our research was focused on the functions miR-494 Ep and its inner mechanisms.Methods modeled rats induced by lithium chloride-pilocarpine were treated with agomir-miR-494 or RIPK1-siRNA. pathology rat hippocampal tissues observed. Expression miR-494, receptor-interacting protein kinase 1 (RIPK1) nuclear factor-kappaB (NF-κB) p65 assessed RT-qPCR Western blot analysis. neurons epileptic...
Abstract The roles of some long non-coding RNAs (lncRNAs) in intracranial aneurysm (IA) have been investigated many studies. aim this study is to elucidate the mechanism lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1)/microRNA-143 (miR-143)/vascular endothelial growth factor-A (VEGFA) signal axis vascular injury-induced IA. MALAT1, miR-143, and VEGFA expression IA tissues normal arterial were detected. Matrix metalloproteinase 9 (MMP-9) tissues, von Willebrand factor...