A5029099446- Hair Growth and Disorders
- RNA regulation and disease
- School Health and Nursing Education
- CRISPR and Genetic Engineering
- Skin Protection and Aging
- Dermatological and COVID-19 studies
- Chemotherapy-related skin toxicity
- Insect Resistance and Genetics
- Youth Development and Social Support
- Cutaneous lymphoproliferative disorders research
- Neuroscience and Neuropharmacology Research
- Psychological Testing and Assessment
- Dermatologic Treatments and Research
- Viral-associated cancers and disorders
- Autoimmune Bullous Skin Diseases
- Genetic and rare skin diseases.
- Insect symbiosis and bacterial influences
- Acne and Rosacea Treatments and Effects
- Eosinophilic Disorders and Syndromes
- Vitamin K Research Studies
- Herpesvirus Infections and Treatments
- melanin and skin pigmentation
- Dermatology and Skin Diseases
- Mosquito-borne diseases and control
- Congenital limb and hand anomalies
University of California, Irvine
2017-2023
American Academy of Dermatology
2022
Small laboratory cage trials of non-drive and gene-drive strains the Asian malaria vector mosquito, Anopheles stephensi, were used to investigate release ratios other strain properties for their impact on transgene spread during simulated population modification. We evaluated effects transgenes survival, male contributions next-generation populations, female reproductive success accumulation gene drive-resistant genomic target sites resulting from nonhomologous end-joining (NHEJ) mutagenesis...
Transposons are a class of selfish DNA elements that can mobilize within genome. If mobilization is accompanied by an increase in copy number (replicative transposition), the transposon may sweep through population until it fixed all its interbreeding members. This introgression has been proposed as basis for drive systems to move genes with desirable phenotypes into target species. One such application would be use them gene conferring resistance malaria parasites throughout vector...
Vaccine-induced adverse events are a concern among both healthy individuals and those with preexisting conditions. The is that the safety of any vaccine cannot be easily generalizable to populations who not routinely included in clinical trials, such as patients chronic autoimmune inflammatory disorders.1 paucity data concerns related disease exacerbations these conditions can serve source hesitancy patients. Several studies have observed or autoinflammatory disorders at-risk postvaccination.
SARS-CoV-2 infection and its inflammatory sequelae have been reported to affect hair, with the most common association being telogen effluvium (TE).1 Onset of TE noted as diffuse thinning following is occur after 1 3 months on average, trichoscopy findings empty hair follicles, thin terminal hairs, 1-hair follicular units.2 Implicated mechanisms include stress disease, proinflammatory cytokine release, or direct viral damage follicles.
Introduction: Clinical examinations of the scalp have shown that patients may grow hair preferentially at higher density on one side their scalp, yet review literature to date has not yield studies directly assess differences in laterality. The objective this study was examine whether growth occurs and which right or left, healthy patients. Method: Scalps subjects with no history loss disease were imaged digital trichoscopy a university dermatology clinic. Bilateral temporal photos uploaded...
In addition to hair loss, alterations in texture can be a worrisome side effect of certain medications yet are seldom reported and poorly characterized.To systematically analyze the scientific literature characterize medication-associated changes.Relevant primary within PubMed Cochrane was reviewed from 1985-2021 including 31 articles (1 randomized controlled trial with changes incidentally noted, 6 cohort, 1 cross-sectional, 23 case studies), comprising 2594 patients.Texture were associated...
Introduction: Dermal “micro-injections" of botulinum toxin A (BTX-A) treatment can improve facial flushing and erythema in patients with refractory rosacea. We present a case patient longstanding papulo-pustular rosacea flushing, to laser, topical systemic therapies, where intradermal microdroplet BTX-A injections successfully controlled flushing. Case Description: 49-year-old White female 4-year history presented bright, central telangiectasias after failing multiple 595 nm pulsed dye...
Abstract We report a case of 13‐year‐old boy who presented with eruptive monomorphic white papules on the trunk and arms involving regions previously affected by toxic epidermal necrolysis (TEN). Biopsy revealed compact keratin hair follicle sparse mixed perivascular infiltrate, findings consistent lichen spinulosus. Improvement was noted after treatment ammonium lactate 12% lotion. While cutaneous dyschromia xerosis are common TEN, spinulosus has not yet been described in literature. It is...
Mast cells, classically known as local effector cells in allergic reactions, have become recognized recent years for their pathogenic contributions to tumor promoting microenvironments.1Rabenhorst A. Schlaak M. Heukamp L.C. et al.Mast play a protumorigenic role primary cutaneous lymphoma.Blood. 2012; 120: 2042-2054https://doi.org/10.1182/blood-2012-03-415638Crossref PubMed Scopus (106) Google Scholar Patients with mastocytosis are at an increased risk myeloid malignancies, emerging evidence...
What is known about this subject in regard to women and their families? While one genome-wide studies few genetic were completed that showed higher frequencies of some alleles amongst with these conditions, information largely sparse. Familial cases frontal fibrosing alopecia (FFA) lichen planopilaris (LPP) the literature have also suggested familial influence but there little data on trends history conditions. new from article as messages for This helps quantify presence a component...
Primary erythromelalgia, while uncommon, may significantly decrease the quality of life those affected. While many patients with erythromelalgia require systemic therapy, there is no standard care for this condition. Herein, we report a 7-year-old girl who experienced resolution symptoms adverse effects after treatment low-dose gabapentin. We also discuss safety and efficacy gabapentin in children pain.
Background/Purpose: According to the California Department of Education, in Orange County (OC), California, almost 37% 5th graders are overweight or obese, and low-income minority youth most impacted. Obesity causes long-term health issues has intergenerational implications [Wang et al., 2019]. Team Kid Power! OC (KiPOW! OC) is an academic-community partnership initiated 2015 support school policies coach Title I elementary schools through on-site mentorship for behavioral change during...