A5030848846- Head and Neck Cancer Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer Diagnosis and Treatment
- Brain Tumor Detection and Classification
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer survivorship and care
- Brain Metastases and Treatment
- Ultrasound and Hyperthermia Applications
- Infrared Thermography in Medicine
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Global Cancer Incidence and Screening
- Glioma Diagnosis and Treatment
- BRCA gene mutations in cancer
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Peripheral Nerve Disorders
- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Palliative Care and End-of-Life Issues
- Sleep and related disorders
- Economic and Financial Impacts of Cancer
- Family Support in Illness
- Health Systems, Economic Evaluations, Quality of Life
- Prenatal Screening and Diagnostics
University of Michigan
2017-2025
Michigan Medicine
2020
Health Services Research & Development
2017
University of Southern California
2017
Germline genetic testing is recommended by practice guidelines for patients diagnosed with cancer to enable genetically targeted treatment and identify relatives who may benefit from personalized screening prevention.
Abstract Study Objectives In a randomized controlled noninferiority trial, we compared face-to-face and telemedicine delivery (via the AASM SleepTM platform) of cognitive-behavioral therapy (CBT) for insomnia improving insomnia/sleep daytime functioning at posttreatment 3-month follow-up. A secondary objective modalities on treatment credibility, satisfaction, therapeutic alliance. Methods total 65 adults with chronic (46 women, 47.2 ± 16.3 years age) were to 6 sessions CBT delivered...
Often misperceived as solely a dental disease, periodontitis is chronic condition characterized by inflammation of the support structures tooth and associated with systemic endothelial dysfunction. Despite affecting almost 40% US adults 30 years age or older, rarely considered when quantifying multimorbidity (the presence 2 more conditions in an individual) burden for our patients. Multimorbidity represents major challenge primary care increasing health expenditure increased...
Abstract Purpose Adjuvant endocrine therapy is recommended to extend beyond five years for stage II breast cancer, with less consensus extension in I. We aimed understand use of and decision-making about extended therapy. Patients Methods Women aged 20-79 diagnosed I-II cancer 2014-15 reported Georgia Los Angeles County SEER registries were surveyed at seven months again six post-diagnosis (N = 2,361; response rate 60%). estrogen receptor (ER) and/or progesterone (PR)-positive disease asked...
Abstract The incidence of HPV16-positive oropharyngeal squamous cell carcinoma (HPV+ OPSCC) is rising at an alarming rate and has overtaken cervical cancer to become the most prevalent HPV+ in United States. Although patients with OPSCC respond favorably standard chemoradiation, a substantial proportion have highly aggressive tumors that recur. Biomarkers are needed reliably stratify into risk subgroups. Using multiple complementary models recapitulate OPSCC, our group demonstrated enhanced...
Purpose Prior studies have suggested a need for greater clarity about provider roles in team-based cancer care; however, little is known patients' preferences regarding which providers handle their care needs after primary treatment. Methods We surveyed women with newly diagnosed stages 0 to II breast who were treated 2014 and 2015 as reported the Georgia Los Angeles SEER registries (N = 2,372; 68% response rate). Patient handles following treatment ascertained: follow-up mammograms,...
Whether surgery or radiotherapy is the preferred treatment for patients with localized prostate cancer continues to be debated, and randomized clinical trials cannot yet fully address this question. Furthermore, there may heterogeneity in responses, optimal a patient will depend on his tumor characteristics.To use unified statistical approach compare association of both metastatic failure (CF) survival develop an online calculator individualized, treatment-specific outcome prediction.Cohort...
Joint models for longitudinal and time-to-event data are useful in situations where an association exists between a marker event time. These typically complicated due to the presence of shared random effects multiple submodels. As consequence, software implementation is warranted that not prohibitively time consuming. While methodological research this area continues, several statistical procedures exist assist fitting some joint models. We review available frequentist Bayesian programming...
PURPOSE To examine receipt of genetic testing and communication with relatives about results into survivorship after diagnosis breast cancer. METHODS Women age 20-79 years diagnosed early-stage cancer in 2014-2015 reported to the Georgia Los Angeles County SEER registries were surveyed approximately 7 months 6 (n = 1,412). We asked counseling, testing, results. categorized women indications for on basis clinical guidelines at time follow-up survey (FUPs). RESULTS A total 47.4% had any time:...
<h3>PURPOSE</h3> We undertook a study to examine national trends in potentially preventable hospitalizations—those for ambulatory care–sensitive conditions that could have been avoided if patients had timely access primary care—across 3,200 counties and various subpopulations of older adults the United States. <h3>METHODS</h3> used 2010-2014 Medicare claims data hospitalizations among beneficiaries aged 65 years developed heat maps county-level variation. generalized estimating equation...
Patients report strong preferences regarding which provider-oncologist or primary care provider (PCP)-handles their after initial cancer treatment (eg, other screenings, preventive care, comorbidity management). Little is known about associations between involvement during and patient for roles treatment.
Objectives Although frequent emergency department (ED) use is a global issue, little research has been conducted in country like Japan where universal health insurance available. The study aims to (1) document the proportion of ED visits that are by users and (2) describe differences characteristics other including expenditures between secondary tertiary hospital. Design A prevalence for period 1 year. Setting hospital central Japan. Participants All patients who presented EDs. Primary...
PURPOSE Very little is known about primary care involvement in the of cancer survivors beyond initial 5 years post-treatment when transitioning to guideline-recommended for many survivors. METHODS The ICanCare study a longitudinal survey women diagnosed with breast 2014-2015 identified Georgia and Los Angeles SEER registries. Women were surveyed during treatment again approximately 6 later survivorship (2021-2022; n = 1,412, 60% response rate). Respondents asked which provider led their...
475 Background: Primary care physicians (PCPs) have varying roles in a patient’s across the cancer continuum. However, little is known about how PCP engagement and communication change over time transition from breast treatment to longer-term survivorship. Methods: The iCanCare study longitudinal of women diagnosed with 2014-15 identified Los Angeles Georgia Surveillance, Epidemiology End Results registries. Women were surveyed during initial again 6 years later survivorship (2021-22)...
Abstract Introduction Telemedicine is increasingly an option for delivery of healthcare services, but its efficacy and acceptability delivering CBT insomnia has not been adequately tested. In a randomized controlled non-inferiority trial, we compared face-to-face telemedicine (via the AASM SleepTM platform) improving sleep daytime functioning at post-treatment 12-week follow-up. Methods Sixty-five adults with chronic (46 women, mean age 47.2 ± 16.3 years) were recruited primarily from...
120 Background: Various oral therapies exist and have improved outcomes for men with prostate cancer. These agents are expensive put patients at risk financial toxicity. Although assistance mechanisms to offset these costs, navigating through can be complicated places excess burdens on patients. We conducted a survey of prescribed cancer assess toxicity perceptions the process obtaining medications Methods: Patients who had been abiraterone, enzalutamide, apalutamide or darolutamide our...
<p>This figure shows that Tongue SCC patients with IND equal or larger than T-AND have poor DSS</p>
<p>This figure show the association of NND with differentiation, Stage, patter invasion and PNI</p>
<p>This figure shows the correlation between depth of invasion and nerve density measurements, nerve-tumor distance in tongue SCC</p>
<div>AbstractPurpose:<p>Perineural invasion (PNI) in oral cavity squamous cell carcinoma (OSCC) is associated with poor survival. Because of the risk recurrence, patients PNI receive additional therapies after surgical resection. Mechanistic studies have shown that nerves tumor microenvironment promote aggressive growth. Therefore, this study, we evaluated whether nerve density (ND) influences growth and patient Moreover, assessed reliability artificial intelligence (AI)...