Zhi Li

ORCID: 0000-0001-8089-5964
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Animal Nutrition and Physiology
  • Aquaculture disease management and microbiota
  • Bacterial Infections and Vaccines
  • Pneumonia and Respiratory Infections
  • Invertebrate Immune Response Mechanisms
  • Biochemical and Structural Characterization
  • Aquaculture Nutrition and Growth
  • Meat and Animal Product Quality
  • SARS-CoV-2 and COVID-19 Research
  • Graphene and Nanomaterials Applications
  • Rabbits: Nutrition, Reproduction, Health
  • Oral microbiology and periodontitis research
  • Insect Utilization and Effects
  • Hong Kong and Taiwan Politics
  • Antibiotic Resistance in Bacteria
  • Nutritional Studies and Diet
  • Heme Oxygenase-1 and Carbon Monoxide
  • RNA Interference and Gene Delivery
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Toxoplasma gondii Research Studies
  • Cytomegalovirus and herpesvirus research
  • Infant Nutrition and Health
  • Peptidase Inhibition and Analysis
  • Virology and Viral Diseases

City University of Macau
2025

Shaanxi Normal University
2012-2024

Shanghai Municipal Center For Disease Control Prevention
2024

Hebei Normal University
2024

Northeast Agricultural University
2022

Ocean University of China
2022

Feed Research Institute
2019-2021

Zhejiang University
2016-2021

Sun Yat-sen University
2013

Thang Long University
2012

Defensins are a group of cationic peptides that exhibit broad-spectrum antimicrobial activity. In this study, we cloned and characterized β-defensin from pituitary cDNA library protogynous hermaphroditic orange-spotted grouper (Epinephelus coioides). Interestingly, the was shown to be dominantly expressed in testis by RT-PCR Western blot analysis, its transcript level is significantly upregulated reproduction organs intersexual gonad during natural artificial sex reversal. Promoter sequence...

10.1371/journal.pone.0012883 article EN cc-by PLoS ONE 2010-12-20

The proliferation of short video platforms has transformed digital interaction and content consumption, making them pivotal in everyday life. Despite their widespread popularity, these frequently overlook the needs users with disabilities, who face significant barriers terms both accessibility participation. This paper examines current challenges opportunities for enhancing inclusivity on within Chinese context, emphasising gaps design, moderation algorithmic fairness. It underscores...

10.1080/09687599.2025.2451684 article EN other-oa Disability & Society 2025-01-17

Abstract Background Antibiotic growth promoters are widely used to improve weight gain. However, the abuse of antibiotics can have many negative effects on people. Developing alternatives is an urgent need in livestock production. We aimed perform a meta-analysis and network (NMA) investigate feed additives as potential antibiotic substitutes (ASs) bacteriostasis, performance, intestinal morphology immunity. Furthermore, primary, secondary, tertiary ASs were defined by comparing their...

10.1186/s40104-020-00534-2 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2021-01-07

Rats are naturally resistant to Toxoplasma gondii infection, particularly the RH strain, while mice not. Previous studies have demonstrated that inducible nitric oxide synthase (iNOS) and arginase-1 of rodent peritoneal macrophages linked mechanism resistance. As an increasing number on human animal infections showing pulmonary toxoplasmosis is one most severe clinical signs from T. we interested know whether infection in alveolar rats also levels iNOS activity. Our results demonstrate could...

10.1371/journal.pone.0063650 article EN cc-by PLoS ONE 2013-05-15

Antimicrobial peptides are effector molecules of the innate immunity amphibians. Here, one antimicrobial peptide cDNA precursor, prepropalustrin-2CE3, from tadpole Chinese brown frog Rana chensinensis was cloned. The coding sequence corresponding to mature palustrin-2CE subcloned into pGEX-6p-1. soluble GST-palustrin-2CE fusion protein successfully expressed in BL21(DE3)pLysS strain at 16 °C, and proportion reached 35%-39% total cellular protein. After removal GST-fusion tag, purity obtained...

10.1271/bbb.110672 article EN Bioscience Biotechnology and Biochemistry 2012-01-09

In recent years, notified pertussis cases have been increasingly documented in China. It raised a new public health concern of potential optimization immunization strategy. This study was aimed to determine the cost-effectiveness different strategies against pertussis-containing vaccines for 6-year-old pre-school children Shanghai.

10.1016/j.vaccine.2024.126162 article EN cc-by Vaccine 2024-07-27

Supplementation of feed with long-chain fatty acids (LCFAs) during the grower and finisher phases has long been discussed as a growth promotion strategy in pigs, but its effects are inconsistent. The purpose our study was to comprehensively evaluate on performance based average daily gain (ADG), intake (ADFI) gain: (G:F) ratio unveil roles basal diet, LCFA concentration saturation. We searched PubMed Web Science databases (articles published from Jan 1st, 2000, Sep 30th, 2018; restricted...

10.1186/s40104-019-0374-1 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2019-08-15

An antibacterial membrane, consisting of PDMS and TBBPA coated with a human immunoglobulin G modified MnO<sub>2</sub> nanowire monolayer, was applied to capture eliminate <italic>Staphylococcus aureus</italic> promote infected wound healing.

10.1039/c9tb00394k article EN Journal of Materials Chemistry B 2019-01-01

Abstract Fermented feed (FF) is recommended due to its high nutritional value and digestibility, but effects on pig growth performance are inconsistent. This meta-analysis was conducted quantify the of FF performance. We systematically searched in PubMed Web Science for studies (published between January 1, 2000 December 20, 2018) comparing supplementation with basal diet The main outcomes were average daily gain (ADG), intake (ADFI), gain: ratio (G/F). Random-effects model used compute...

10.1093/jas/skz258.258 article EN Journal of Animal Science 2019-12-01

Aim: The response of E. coli ATCC8739 to Brevinin-2CE (B2CE) was evaluated as a strategy prevent the development antimicrobial peptide (AMP)-resistant bacteria. Methods: Gene expression levels were detected by transcriptome sequencing and RT-PCR. Target genes knocked out using CRISPR-Cas9. MIC measured evaluate strain resistance. Results: Expression acrZ sugE increased with B2CE stimulation. ATCC8739ΔacrZ ATCC8739ΔsugE showed twofold fourfold sensitivity, respectively. survival rate reduced...

10.2217/fmb-2023-0272 article EN Future Microbiology 2024-04-29

Palustrin-2CE2 and brevinin-2CE3 are antimicrobial peptides from Rana chensinensis. In R. chensinensis tadpoles, the expression of prepropalustrin-2CE2 preprobrevinin-2CE3 increased with developmental stage. addition, two genes was dramatically upregulated stimulation by Escherichia coli, Staphylococcus aureus, chemical lipopolysaccharide (LPS). The genomic organization peptide confirmed. Both contain three exons separated large introns. Additionally, several presumed transcription factor...

10.2174/0929866528666211125105627 article EN Protein and Peptide Letters 2021-11-26
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