A5009003230- COVID-19 Impact on Reproduction
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Maternal Mental Health During Pregnancy and Postpartum
- Vaccine Coverage and Hesitancy
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- COVID-19 and healthcare impacts
- Hepatitis B Virus Studies
- Birth, Development, and Health
- Cervical Cancer and HPV Research
- COVID-19 and Mental Health
- Global Cancer Incidence and Screening
- Global Maternal and Child Health
- Healthcare Systems and Reforms
- Ophthalmology and Eye Disorders
- Quantum Electrodynamics and Casimir Effect
- Gastrointestinal disorders and treatments
- Fetal and Pediatric Neurological Disorders
- Ethics and Legal Issues in Pediatric Healthcare
- Clinical practice guidelines implementation
- GDF15 and Related Biomarkers
- Air Quality and Health Impacts
- HIV/AIDS Research and Interventions
Icahn School of Medicine at Mount Sinai
2018-2025
Mount Sinai Health System
2022
Mount Sinai Hospital
2022
Women's Health Research Institute
2021
Institute of Population and Public Health
2021
University of California, San Francisco
2012
Institute of Biophysics
2006
Pine Street Foundation
2006
Abstract Background Recent meta-analyses showed that around 30% of women suffered postpartum depression during the COVID-19 pandemic, a two-fold increase compared to before pandemic (1,2,3). The immune system plays key role in responding infections, and is potential mechanism development psychiatric disorders. placenta driver changes pregnancy, modulating maternal response perinatal infections (4). Aims & Objectives To investigate: 1) whether SARS-CoV2 infection pregnancy associated with...
Abstract Background The SARS-CoV-2 vaccine is a key tool for protection against severe COVID-19 disease during pregnancy (1). However, the brief strong inflammatory reaction that occurs after vaccination may impact postpartum depressive symptoms as proposed by neuroinflammatory hypothesis of depression (2). Aims and Objectives This study aims to examine potential association between SARS- CoV-2 depression. Method Participants (n=627) were enrolled in CDC-funded Generation C (n=564) or...
The COVID-19 pandemic is an ongoing global health threat, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Questions remain about how SARS-CoV-2 impacts pregnant individuals and their children.
Associations between antenatal SARS-CoV-2 infection and pregnancy outcomes have been conflicting the role of immune system is currently unclear. This prospective cohort study investigated interaction infection, changes in cytokine HS-CRP levels, birthweight gestational age at birth. 2,352 pregnant participants from New York City (2020-2022) were included. Plasma levels interleukin (IL)-1β, IL-6, IL-17A high-sensitivity C-reactive protein (HS-CRP) quantified blood specimens obtained across...
Adaptations of the immune system throughout gestation have been proposed as important mechanisms regulating successful pregnancy. Dysregulation maternal has associated with adverse and fetal outcomes. To translate findings from mechanistic preclinical studies to human pregnancies, serum markers are mainstay. The design interpretation biomarker require additional insights in trajectories drivers peripheral markers. current study mapped inflammatory (C-reactive protein (CRP), interleukin...
Abstract The influence of ciamexone on the activity and course endocrine orbitopathy was investigated. Fifty-one patients with active classes II-VI were allocated randomly to two groups: over a period six months, 26 received 300 mg/day 25 placebo tablets. In both groups, prednisolone administered in addition first four weeks. Ophthalmological investigations clinical tests as well orbit sonography carried out before one, three months after beginning therapy. Before treatment, computer...
Disturbances in T-cells, specifically the Th17/Treg balance, have been implicated adverse pregnancy outcomes. We investigated these two T-cell populations following pre-pregnancy and SARS-CoV-2 infection COVID-19 vaccination 351 participants from a cohort New York City (Generation C; 2020-2022). status was determined via laboratory or medical diagnosis survey electronic records data. Peripheral blood mononuclear cells (PBMCs) were collected at routine prenatal visits throughout gestation...
The aim of this study was to assess human papillomavirus (HPV) prevalence, knowledge, attitudes, and practices, among men who have sex with (MSM) in Monrovia, Liberia.This cross-sectional conducted 107 MSM, aged 18 58 years, completing questionnaires anal HPV screenings. Using peer-educators direct community involvement, demographics, risk factors, knowledge data were collected.Forty-eight participants (45%) positive 21 (19.6%) self-identified as HIV positive. When examining 22 reported...
Cervical cancer is the most common in reproductive aged women Liberia. Lack of awareness and screening capacity are both major contributors to prevalence this disease. The minority Muslim population country largely unscreened. objective study was assess cervical risk factors preferences among living Monrovia, Liberia offer self-screening with HPV testing. A multiple step implementation strategy devised order outreach engagement community religious leaders, about an upcoming program...
The coronavirus disease 2019 (COVID-19) pandemic rapidly overwhelmed global health care systems in 2020, with New York City (NYC) marking the first epicenter United States. High levels of stress amongst workers have been reported pandemics, but less is known about Obstetrics and Gynecology (OB/GYN) providers. We sought to describe stress, anxiety, depression, other aspects mental among OB/GYN during wave COVID-19 pandemic.We conducted an anonymous cross-sectional electronic survey a wide...
<strong>Background:</strong> Viral hepatitis is a leading cause of death worldwide, with higher mortality rate than that from human immunodeficiency virus (HIV), tuberculosis (TB) or malaria. In order to meet the WHO's goal eliminating B and C by 2030, there dire need establish baseline prevalence rates increase public health awareness this detrimental disease, especially in low middle-income countries (LMICs) where establishing (HBV) (HCV) continues be problem. <strong>Objective:</strong>...
We examined differences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses pregnant individuals with natural, vaccine-induced, or combined immunity. Participants had live nonlive births between 2020 and 2022, were seropositive (SARS-CoV-2 spike protein, anti-S), available mRNA vaccination infection information (n=260). compared titer levels among three immunity profiles: 1) natural (n=191), 2) vaccine-induced (n=37), 3) (ie, immunity; n=32). applied linear...
Abstract Background In May-July 2020 in the New York City area, up to 16% of pregnant women had reportedly been infected with SARS-CoV-2. Prior studies found associations between SARS-CoV-2 infection during pregnancy and certain adverse outcomes (e.g., preterm birth, cesarean delivery). These relied on reverse transcription polymerase chain reaction (RT-PCR) testing establish infection. This led overrepresentation symptomatic or acutely ill cases scientific studies. Objective To expand our...
Aim This study aims to assess the effect of implementing an enhanced prenatal genetic checklist guide provider's discussion on both screening and diagnostic options for fetal aneuploidy testing at initial visit. Methods A retrospective quality improvement (QI) project was performed a single, large, urban academic medical center. The implementation this prospective; however, data examined retrospectively after QI initiative implemented three months. Patients were included if they less than 24...