- Veterinary Medicine and Surgery
- Veterinary Pharmacology and Anesthesia
- Inflammatory mediators and NSAID effects
- Rabbits: Nutrition, Reproduction, Health
- Maternal Mental Health During Pregnancy and Postpartum
- Pharmacological Effects of Natural Compounds
- Assisted Reproductive Technology and Twin Pregnancy
- Turtle Biology and Conservation
- Pharmacogenetics and Drug Metabolism
- Emergency and Acute Care Studies
- Veterinary Oncology Research
- Microbial infections and disease research
- Patient Safety and Medication Errors
- Veterinary Equine Medical Research
- Anesthesia and Sedative Agents
- Birth, Development, and Health
- Rabies epidemiology and control
- Hedgehog Signaling Pathway Studies
- Healthcare Policy and Management
- Congenital Anomalies and Fetal Surgery
- Animal Behavior and Reproduction
- Veterinary Orthopedics and Neurology
- GDF15 and Related Biomarkers
- Animal Virus Infections Studies
- Oral microbiology and periodontitis research
Zoological Society of San Diego
2024-2025
University of California, Davis
2022-2025
Tufts University
2024
Icahn School of Medicine at Mount Sinai
2024
Kansas State University
2020-2023
St. James's Hospital
2008-2009
Nenagh Hospital
2009
Tallaght University Hospital
2008
Aim: To develop and validate an in-hospital mortality risk prediction tool for unselected acutely ill medical patients using routinely collected physiological laboratory data. Design: Analysis of all emergency admitted to St James's Hospital (SJH), Dublin, between 1 January 2002 31 December 2007. Validation a dataset acute admissions from Nenagh 2000–04. Methods: Using vital signs findings, composite 5-day score, designated system (MARS), was developed iterative approach involving logistic...
Aim: To determine the impact of introduction an acute medical admission unit (AMAU) on all-cause hospital mortality in unselected patients undergoing to a teaching hospital. Design: Analysis data recorded in-patient enquiry (HIPE) system relating all emergency admitted St James's Hospital (SJH), Dublin between 1 January 2002 and 31 December 2006. Methods: The reference year was 2002, during which were variety wards under care named consultant physician. In 2003, two centrally located...
Veterinary intervention in zoological species can be complicated by species-specific social dynamics. African wild dogs are a pack and removal or separation of an individual may disrupt established hierarchy resulting conspecific aggression. Therefore, medical interventions that optimize quick return to health ideal minimize the duration absence from pack. These principles were utilized for three-year-old male intact zoo-housed dog (AWD) presented with episode severe, acute, right-sided...
Abstract Black-tailed prairie dogs (Cynomys ludovicianus) are keystone species within their grassland ecosystems; population stability affects a multitude of other species. The goals this study were to explore, describe and compare the bacterial communities in caecal hard faecal samples from free-ranging black-tailed (n = 36) KS, USA, using high-throughput sequencing V4 region 16S rRNA gene sex geographic locations. A total 22 paired collected post-mortem 5 different geographical results...
To determine the pharmacokinetics of a solution containing cannabidiol (CBD) and cannabidiolic acid (CBDA), administered orally in 2 single-dose studies (with without food), domestic rabbit (Oryctolagus cuniculus).6 healthy New Zealand White rabbits.In phase 1, 6 rabbits were 15 mg/kg CBD with 16.4 CBDA hemp oil. In 2, same dose oil followed by food slurry. Blood samples collected for 24 hours to CBDA. Quantification plasma concentrations was determined using validated liquid...
To examine the pharmacokinetics and ex vivo pharmacodynamics of oral firocoxib administration in New Zealand White rabbits (Oryctolagus cuniculus).6 healthy rabbits.Pharmacokinetics were determined from plasma concentrations measured via ultra performance liquid chromatography-tandem mass spectrometry after at a dose 3.74 to 4.20 mg/kg. Pharmacokinetic analysis was performed using non compartmental methods. Pharmacodynamics evaluated by measuring thromboxane prostaglandin ELISAs as surrogate...
Abstract Aims Q fever is a globally distributed, neglected zoonotic disease of conservation and public health importance, caused by the bacterium Coxiella burnetii. burnetii normally causes subclinical infections in livestock, but may also cause reproductive pathology spontaneous abortions artiodactyl species. One such artiodactyl, dromedary camel ( Camelus dromedarius ), an increasingly important livestock species semi‐arid landscapes. Ticks are naturally infected with C. worldwide...
Pain management in rabbits is a challenging task that complicated by the rabbit's ability to hide signs of distress and limited pharmacologic data available for this species. Pharmacokinetic has shown rabbits, meloxicam, nonsteroidal anti-inflammatory NSAID, reaches plasma concentrations are known provide analgesia dogs cats; these could theoretically alleviate pain rabbits. However, inhibitory effects meloxicam on cyclooxygenase (COX) isoforms have not been studied In study, we measured...
Two central bearded dragons (Pogona vitticeps), a 3-y-old male and 5-y-old female, were diagnosed with different manifestations of lymphoma at the Kansas State Veterinary Diagnostic Laboratory between 2019 2020. The was presented for postmortem evaluation in poor body condition. Microscopically, nearly all examined organs contained variable numbers neoplastic round cells. Neoplastic cells stomach liver had moderate immunoreactivity to CD3 consistent multicentric T-cell lymphoma,...
Effective rabbit analgesia is challenging, and there are few studies available on the newer COX-2 selective NSAIDs, such as robenacoxib. This study aimed to establish pharmacokinetics of oral subcutaneous robenacoxib, describe its inhibitory actions COX enzymes, develop dosing, using six healthy New Zealand white rabbits. Pharmacokinetics were determined from plasma concentrations after administration robenacoxib (0.83-0.96 mg/kg) also (2 mg/kg). The evaluated by measuring thromboxane B2...
Objectives To determine the association between signalment, selected haematologic and biochemical parameters referral centre in pet rabbits with imaging evidence of urolithiasis presented to two veterinary teaching hospitals North America. Materials Methods The medical record database was searched from 2009 2019 for records that received both studies plasma biochemistry profiles. Information regarding bodyweight, packed cell volume, total solids, profiles obtained. Univariable multivariable...
A 4-year-old female spayed domestic ferret (Mustela putorius furo) presented with a history of vomiting over 24 hours. On physical examination, significantly enlarged, firm spleen was palpated. Abdominal radiographs and abdominal ultrasound were suggestive splenic torsion or infarction. An exploratory laparotomy confirmed the initial diagnosis splenectomy performed using vessel sealing device. Histologic evaluation culture consistent primary without evidence infection neoplasia. The patient...
This study provides ultrasonographic fetal growth charts for the Eastern black-and-white colobus monkey (Colobus guereza). Throughout three consecutive gestations (-162 to -2 days parturition) in a single dam, we opportunistically obtained measurements following parameters: biparietal diameter, head circumference, humerus length, femur tibia radius thoracic width, kidney and crown-rump length. Biparietal diameter was most consistently measured parameter. First detection of fetuses occurred...
To determine severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) serum antibody titers in domestic goats after SC and IM administration of an experimental, veterinary SARS-CoV-2 vaccine.31 healthy adult from 4 zoological institutions.On day 0, blood was collected for baseline titer before vaccination with 1 mL recombinant S protein vaccine (n = 22) or 9). A booster administered 21 (SC group) 28 days (IM the initial samples were at group), 42, 90, 180 postvaccinations. The study took...
Abstract A 14‐year‐old female black and white colobus monkey (Colobus guereza) presented in labor with fetal arms visible protruding from the vulva. Manual manipulation for assisted delivery of fetus was unsuccessful. Radiographs identified a large skull hysterotomy required ovariohysterectomy elected to follow. The confirmed be deceased during hysterotomy, but dam recovered procedure uneventfully. detailed description anesthesia surgical this case may aid other clinicians when similar...