A5100758319- Advanced Fluorescence Microscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Plasmonic and Surface Plasmon Research
- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Optical Coherence Tomography Applications
- Advanced biosensing and bioanalysis techniques
- Advanced Electron Microscopy Techniques and Applications
- Photonic Crystals and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Quantum Dots Synthesis And Properties
- Photonic and Optical Devices
- Perovskite Materials and Applications
- Optical Coatings and Gratings
- Near-Field Optical Microscopy
- Metamaterials and Metasurfaces Applications
- 2D Materials and Applications
- Photodynamic Therapy Research Studies
- Cell Image Analysis Techniques
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Optical Imaging and Spectroscopy Techniques
- Marine Biology and Environmental Chemistry
- Advanced Optical Sensing Technologies
Shenzhen University
2016-2025
State Council of the People's Republic of China
2019
Ministry of Education of the People's Republic of China
2015
Central South University
2011-2013
Antimonene-based 2D materials are attracting increasing research interest due to their superior physicochemical properties and promising applications in next-generation electronics optoelectronics devices. However, the semiconductor of antimonene still at theoretical simulation stage not experimentally verified, significantly restricting its specific areas. In this study, monolayer nanosheets verified. It is found that obtained semiconductive (SANs) exhibit indirect bandgap properties, with...
Abstract Stimulated emission depletion (STED) nanoscopy is one of the most promising super‐resolution imaging techniques for microstructure imaging. Commercial CdSe@ZnS quantum dots are used as STED probes and ≈50 nm lateral resolution obtained. Compared with other dots, perovskite CsPbBr 3 nanoparticles (NPs) possess higher photoluminescence yield larger absorption cross‐section, making them a more effective probe nanoscopy. In this study, NPs The fluorescence intensity sample hardly...
Electro-induced reduction of redox active esters and N-phthalimidoyl oxalates derived from naturally abundant carboxylic acids alcohols provides a sustainable inexpensive approach to radical formation via undivided electrochemical cells. The resulting radicals are trapped by an electron-poor olefin or hydrogen atom source furnish the Giese reaction reductive decarboxylation products, respectively. A broad range acid (1°, 2°, 3°) alcohol (2° derivatives applicable in this catalyst-free...
Abstract Timely and accurately identification of the novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) infection can greatly contribute to monitoring controlling global pandemic. This study gained theoretical insight into a phase-modulation plasmonic biosensor working in near-infrared (NIR) regime, which be employed for sensitive detection SARS-CoV-2 its spike (S) glycoprotein. The proposed was created integrating two-dimensional (2D) Van...
Abstract Marine bacteria have been considered as important participants in revealing various carbon/sulfur/nitrogen cycles of marine ecosystem. Thus, how to accurately identify rare without a culture process is significant and valuable. In this work, we constructed single‐cell Raman spectra dataset from five living spores utilized convolutional neural network rapidly, accurately, nondestructively spores. The optimal CNN architecture can provide prediction accuracy spore high 94.93% ± 1.78%....
Stimulated emission depletion (STED) microscopy is a powerful super-resolution technique that has achieved significant results in breaking the resolution limit and relevant applications.
This paper presents and demonstrates a new method for the detection of single nanoparticles with photonic nanojet.
Molecular organization of a cell is dynamically transformed along the course cellular physiological processes, pathologic developments or derived from interactions with drugs.The capability to measure and monitor concentrations macromolecules in single would greatly enhance studies processes heterogeneous populations.In this communication, we introduce experimentally validate bio-analytical single-cell assay, wherein overall concentration estimated specific subcellular domains, such as...
A ladder-conjugated perylene diimide dimer containing an indacenodithiophene unit was developed and used as a high efficiency electron transport layer in inverted perovskite solar cells.
The rapid development of advanced optical imaging methods including stimulated emission depletion (STED) and fluorescence lifetime microscopy (FLIM) has provided powerful tools for real-time observation submicrometer biotargets to achieve unprecedented spatial temporal resolutions. However, the practical qualities are often limited by performance fluorescent probes, leading unsatisfactory results. In particular, long-term nucleic acids in living cells with STED FLIM remained desirable yet...
A multifunctional fluorescence imaging system based on LabVIEW has been developed, which can perform intensity scanning imaging, and lifetime (FLIM). The utilizes software to control a Data Acquisition (DAQ) card, Time-Correlated Single Photon Counting (TCSPC) galvanometer achieve point-scan imaging. FLIM module integrates Dynamic Link Libraries (DLLs) for control, allowing simultaneous management of the while outputting clock synchronization signals from DAQ card as trigger FLIM. This...
Abstract Nuclear organelles are viscous droplets, created by concentration-dependent condensation and liquid–liquid phase separation of soluble proteins. have been actively investigated for their role in cellular regulation disease. However, these studies highly challenging to perform live cells, therefore, physico-chemical properties still poorly understood. In this study, we describe a fluorescence lifetime imaging approach real-time monitoring protein nuclear cultured cells. This unravels...
Abstract Image‐guided photodynamic therapy (PDT) has received growing attention due to its non‐invasiveness and precise controllability. However, the PDT efficiency of most photosensitizers are decreased in living system aggregation‐caused singlet oxygen ( 1 O 2 ) generation decreasing. Herein, we present an Iridium (III) pyridylpyrrole complex (Ir‐1) featuring aggregation‐induced emission (AIE) characteristics for image‐guided cancer. Ir‐1 aqueous solution exhibits bright red...
Optical imaging is a most useful and widespread technique for the investigation of structure function cellular genomes. However, an analysis immensely convoluted irregularly compacted DNA polymer highly challenging even by modern super-resolution microscopy approaches. Here we propose fluorescence lifetime (FLIM) advancement studies genomic including compaction, replication as well monitoring gene expression. The proposed FLIM assay employs two independent mechanisms compaction sensing. One...
This study proposed a novel Fano resonance (FR) biosensor with ultrahigh detection sensitivity by integrating two dimensional (2D) hexagonal boron nitride (h-BN) nanosheets plasmonic silver film-silicon hybrid nanostructure. Owing to its ultralow-loss in surface plasmon polaritons (SPPs), 2D h-BN can act as planar photon waveguide (PWG) for generating energy level splitting. Notably, both asymmetric FR sharp lines and induced transparency (PIT) be produced modulating the coupling strength...