A5100696381- Obstructive Sleep Apnea Research
- Cancer-related molecular mechanisms research
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
- Sleep and Wakefulness Research
- Congenital Diaphragmatic Hernia Studies
- Sleep and related disorders
- Neuroscience of respiration and sleep
- Autoimmune and Inflammatory Disorders Research
- Head and Neck Cancer Studies
- Peptidase Inhibition and Analysis
- Child Nutrition and Feeding Issues
- Sleep and Work-Related Fatigue
- MicroRNA in disease regulation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infant Development and Preterm Care
- Hematopoietic Stem Cell Transplantation
- Circular RNAs in diseases
- Cardiovascular Health and Disease Prevention
- Toxin Mechanisms and Immunotoxins
Southern University of Science and Technology
2020-2024
Jinan University
2011-2024
Chinese University of Hong Kong
2024
University of Hong Kong
2024
ShenZhen People’s Hospital
2020
Southern Medical University
2017
Guangdong General Hospital
2017
Guangdong Academy of Medical Sciences
2017
Technical University of Nova Scotia
2002
Study Objectives: Wearable sleep recording devices may be a helpful alternative method for polysomnography (PSG) due to their higher accessibility and comfort as well lower cost, but validities need examined.The aim of this study was evaluate the accuracy novel single-channel, electroencephalography-based wearable forehead recorder (UMindSleep) assess staging oxygen desaturation.Methods: Two hundred three Chinese adults recruited from medicine center underwent an overnight wearing UMindSleep...
Objective: To evaluate the clinical performance of OPPO Watch (OW) Sleep Analyzer (OWSA) on OSA screening with polysomnography reference. Methods: We recruited 350 participants using OWSA and PSG simultaneously in a sleep laboratory. The respiratory event index (REI) derived from apnea-hypopnea (AHI) provided by were compared. SHapley Additive exPlanation (SHAP) values calculated to explain model OWSA. Results: OWSA-REI (26.5± 18.5 events/h) correlated well PSG-AHI (33.2± 25.7 events/h; r =...
Bronchopulmonary dysplasia (BPD) is a severe chronic lung disease in preterm infants. Circular RNAs (circRNAs) are key regulators of various biological processes. The present study aimed to explore the roles circRNAs BPD pathogenesis.A newborn rat model was developed construct circRNA library; Illumina deep sequencing (Illumina, San Diego, CA, USA) used reveal differential expression hyperoxia-induced models. Sanger and reverse transcription-polymerase chain reaction were performed confirm...
Pediatric obstructive sleep apnea (OSA) is a frequent respiratory disorder with an estimated prevalence of 3-6% in the general population. However, underlying pathophysiology OSA remains unclear. Recently, proteomic analysis using high-resolution and high-throughput mass spectrometry has been widely used field medical sciences. In present study, tandem tag (TMT)-based was performed serum patients OSA. The revealed set differentially expressed proteins that may be associated were enriched...
Excessive daytime sleepiness (EDS) is considered to be one of the main clinical manifestations obstructive sleep apnea (OSA) and a treatment target for patients with OSA. The prevalence EDS in OSA remains unclear there lack studies on associations quality life among China. This study aimed evaluate its association Shenzhen, cross-sectional included diagnosed [apnea-hypopnea index (AHI) ≥5] at Shenzhen People's Hospital China between May 21, 2023 November 30, 2023. Differences demographics,...
Objective To observe the dynamic expression changes of microRNA(miR)-146a and miR-29 in neonatal rats with acute lung injury (ALI) induced by lipopolysaccharide (LPS), to explore their influence on ALI. Methods Totally 80 newborn aged 7 days were randomly assigned into LPS group control group.Intraperitoneal injection endotoxin(5 mg/kg) was done establish rat model ALI group.Rats intraperitoneally injected 0.1 mL 9 g/L saline.Lung tissue blood specimens from taken at 6 hours, 1 day, 3...
Human pulmonary circulation is studied by using a quasi-one-dimensional unsteady nonlinear fluid model. It applied to 17 generations of blood vessels composed the branching arterial, capillary, and venous distensible vessel segments which make up complete circulation. An idealized pressure-area relation introduced describing varying degrees collapse. The model gives satisfactory agreement with experimental data: dramatic pressure drop occurs in arterioles postcapillaries, negative transmural...