A5080297191- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Streptococcal Infections and Treatments
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Inflammatory mediators and NSAID effects
- Veterinary medicine and infectious diseases
- Bacterial biofilms and quorum sensing
- Neonatal and Maternal Infections
- Click Chemistry and Applications
- RNA and protein synthesis mechanisms
- Receptor Mechanisms and Signaling
- Microbial infections and disease research
- Neuropeptides and Animal Physiology
- Clostridium difficile and Clostridium perfringens research
- HER2/EGFR in Cancer Research
Normandie Université
2019-2023
Université de Caen Normandie
2016-2023
Université de Sherbrooke
2022
Animal Health Trust
2016-2017
Prostaglandin F2α (PGF2α) is a bioactive lipid derived from arachidonic acid and involved in many physiological pathophysiological processes such as parturition, vascular tone regulation, glaucoma inflammation. It acts by binding to the receptor (FP), G Protein-Coupled Receptor (GPCR) that mediates signaling events engaging intracellular heterotrimeric protein effectors. The orthosteric site of lipid-binding receptors displays greater efficacy-dependent plasticity hinders design ligands....
Enterococcus faecalis is a commensal bacterium of the gastrointestinal tract but also major nosocomial pathogen. This uses regulators like BglG/SacY family transcriptional antiterminators to adapt its metabolism during host colonization. In this report, we investigated role antiterminator NagY in regulation nagY-nagE operon presence N-acetylglucosamine, with nagE encoding transporter carbohydrate, as well expression virulence factor HylA. We showed that last protein involved biofilm...
The control of mRNA turnover is essential in bacteria to allow rapid adaptation, especially opportunistic pathogen like Enterococcus faecalis. This mechanism involves RNase and DEAD-box helicases that are key elements RNA processing their associations form the degradosome with accessory proteins. In this study, we investigated function four RNases (J1, J2, Y III) three (CshA, CshB, CshC) present most Enterococci. interactions all these metabolism actors were vitro, results accordance a...