A5033029807- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Abdominal Trauma and Injuries
- Ergonomics and Musculoskeletal Disorders
- Radiation Dose and Imaging
- Acute Ischemic Stroke Management
- Spinal Fractures and Fixation Techniques
- Hemodynamic Monitoring and Therapy
- Musculoskeletal pain and rehabilitation
- Venous Thromboembolism Diagnosis and Management
- Children's Physical and Motor Development
- Cardiovascular Health and Disease Prevention
- Ultrasound in Clinical Applications
- Urinary Tract Infections Management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Intracerebral and Subarachnoid Hemorrhage Research
- Patient Safety and Medication Errors
- Hematological disorders and diagnostics
- Muscle activation and electromyography studies
- Dermatoglyphics and Human Traits
- Gun Ownership and Violence Research
- Elder Abuse and Neglect
The University of Texas Southwestern Medical Center
2015-2025
Children's Hospital of Philadelphia
2024
Medical College of Wisconsin
2015-2024
Boston Children's Hospital
2024
Armed Forces College of Medicine
2023
Montreal Neurological Institute and Hospital
2016-2023
McGill University
2011-2021
McGill University Health Centre
2020-2021
Digestive Care (United States)
2021
Sağlık Bilimleri Üniversitesi
2021
Children with minor head trauma frequently present to emergency departments (EDs). Identifying those traumatic brain injuries (TBIs) can be difficult, and it is unknown whether clinical prediction rules outperform clinician suspicion. Our primary objective was compare the test characteristics of Pediatric Emergency Care Applied Research Network (PECARN) TBI suspicion for identifying children clinically important TBIs (ciTBIs) after blunt trauma. secondary determine reasons obtaining computed...
Lerner, E. Brooke PhD; Drendel, Amy L. DO, MS; Falcone, Richard A. Jr MD, MPH; Weitze, Keith C.; Badawy, Mohamed K. MD; Cooper, Arthur Cushman, Jeremy T. MS, EMT-P; Drayna, Patrick C. Gourlay, David M. Gray, Matthew P. Shah, Manish I. N. MPH Author Information
Abstract Objective The Pediatric Emergency Care Applied Research Network (PECARN) derived and externally validated a clinical prediction rule to identify children with blunt torso trauma at low risk for intraabdominal injuries undergoing acute intervention (IAI AI ). Little is known about the IAI when only one or two variables are positive. We sought determine either PECARN injury Methods performed planned secondary analysis of prospective, multicenter study that included 7542 (<18 years...
Background: There is limited research on how well the American College of Surgeons/Center for Disease Control and Prevention Guidelines Field Triage Injured Patients assist EMS providers in identifying children who need resources a trauma center. Objective: To determine accuracy Physiologic Criteria (Step 1) injured Methods: transported 15 years younger to pediatric centers 3 mid-sized cities were interviewed regarding patient demographics presence or absence each criteria. Children...
Background: In 2011, revised Field Triage Guidelines were released jointly by the Centers for Disease Control and Prevention (CDC) American College of Surgeons – Committee on Trauma (ACS-COT). It is unknown how modifications will affect number injured children identified EMS providers as needing transport to a trauma center. Objective: To determine change in under- over-triage rates when 2011 are compared 2006 1999 versions. Methods: charge care (<15 years) transported pediatric centers 3...
Objective Children evaluated in emergency departments for blunt head trauma (BHT) frequently undergo computed tomography (CT), with some requiring pharmacological sedation. Cranial CT sedation complications are understudied. The objective of this study was to document the frequency, type, and cranial children. Methods We prospectively enrolled children (younger than 18 years) minor BHT presenting 25 from 2004 2006. Data collected included agent complications. excluded patients Glasgow Coma...
Optimal decision-making balances exploration for new information against exploitation of known rewards, a process mediated by the locus coeruleus and its norepinephrine projections. We predicted that an exploitation-bias emerges in older adulthood would be associated with lower microstructural integrity coeruleus. Leveraging vivo histological methods from quantitative MRI-magnetic transfer saturation—we provide evidence age is integrity. Critically, we demonstrate bias adulthood, assessed...
Abstract Objectives Computed tomography ( CT ) is often used in the emergency department ED evaluation of children with posttraumatic seizures PTS ); however, frequency traumatic brain injuries TBI s) and short‐term seizure recurrence lacking. Our main objective was to evaluate s on . We also aimed determine associations between likelihood timing onset after event duration Finally, we whether patients normal scans neurological examinations are safe for discharge from Methods This a planned...
Rationale: Predicting recovery of consciousness in unresponsive, brain-injured individuals has crucial implications for clinical decision-making. Propofol induces distinctive brain network reconfiguration the healthy as it loses consciousness. In patients with disorders consciousness, network’s to propofol may reveal patient’s underlying capacity Objectives: To design and test a new metric prognostication Methods: Using within-subject design, we conducted an anesthetic protocol concomitant...
Abstract Background High-fidelity simulations based on real-life clinical scenarios have frequently been used to improve patient care, knowledge and teamwork in the acute care setting. Still, they are seldom included allergy-immunology curriculum or continuous medical education. Our main goal was assess if critical allergy improved performance Methods Advanced anaphylaxis were designed by a panel of emergency, intensive unit, anesthesiology specialists then adapted for adult clinic This...
Despite the growing evidence of clinical utility blood-brain biomarkers in adults with traumatic brain injury (TBI), less is known about performance these children. We characterize age-dependent differences levels ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) children without TBI.
To determine if the Mechanism of Injury Criteria Field Triage Decision Scheme (FTDS) are accurate for identifying children who need resources a trauma center.EMS providers transporting any injured child ≤15 years, regardless severity, to pediatric center in 3 midsized communities over years were interviewed. Data collected through interview included EMS observed physiologic condition, suspected anatomic injuries, and mechanism. Patients then followed they needed by reviewing their medical...
Abstract Background Real-time automated analysis of videos the microvasculature is an essential step in development research protocols and clinical algorithms that incorporate point-of-care microvascular analysis. In response to call for validation studies available software by European Society Intensive Care Medicine, building on a previous study sheep, we report first human AVA 4. Methods Two retrospective perioperative datasets microcirculation (P1 P2) one prospective healthy volunteer...
Neuroimaging methods have improved the accuracy of diagnosis in patients with disorders consciousness (DOC), but novel, clinically translatable for prognosticating this population are still needed. In case series, we explored association between topographic and global brain network properties prognosis DOC. We recorded high-density electroencephalograms three acute or chronic DOC, two whom also underwent an anesthetic protocol. these cases, compared functional motifs, hubs power topography...
The development and use of seatbelts has saved numerous lives prevented serious injuries in the setting automobile crashes. However, restraints designed for adults are not necessarily effective preventing injury to small children may actually be harmful. Here, we present a case upper cervical spine fracture 5-year-old female patient caused by neck flexion over an inappropriately applied adult 3-point seatbelt during motor vehicle collision. American Academy Pediatrics currently advises...