A5006216677- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Inhalation and Respiratory Drug Delivery
- SARS-CoV-2 detection and testing
- Dental Research and COVID-19
- Infection Control in Healthcare
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- Leptospirosis research and findings
- Respiratory viral infections research
- Thermal Regulation in Medicine
- Malaria Research and Control
- Biosensors and Analytical Detection
- Antimicrobial Resistance in Staphylococcus
- Respiratory Support and Mechanisms
- COVID-19 Impact on Reproduction
- Noise Effects and Management
- Poxvirus research and outbreaks
- Dengue and Mosquito Control Research
- Mycobacterium research and diagnosis
- Vector-borne infectious diseases
- Herpesvirus Infections and Treatments
Bangalore Baptist Hospital
2020-2024
Abstract People living in urban slums or informal settlements are among the most vulnerable communities, highly susceptible to coronavirus disease 2019 (COVID-19) infection and consequences of measures taken control spread virus. Fear stigma related infection, mistrust between officials population, often-asymptomatic nature is likely lead under-reporting. We conducted a cross-sectional study determine seroprevalence COVID-19 large slum South India 3 months after index case recruited 499...
Objectives We aimed to estimate the seroprevalence of COVID-19 in a rural district South India, six months after index case. Methodology conducted cross-sectional study 509 adults aged more than 18 years. From all four subdistricts, two grampanchayats (administrative cluster 5–8 villages) were randomly selected followed by one village through convenience. The participants invited for community-based kiosk set up eight villages health committees. collected socio-demographic characteristics...
Abstract Dehydration of the upper airways increases risks respiratory diseases from COVID-19 to asthma and COPD. We find in human volunteer studies involving 464 subjects Germany, US, India that droplet generation by up 4 orders magnitude dehydration-associated states advanced age (n = 357), elevated BMI-age 148), strenuous exercise 20) SARS-CoV-2 infection 87), falls with hydration nose, larynx trachea calcium-rich hypertonic salts. also a protocol exercise-induced airway dehydration salts...
There are limited global data on head-to-head comparisons of vaccine platforms assessing both humoral and cellular immune responses, stratified by pre-vaccination serostatus. The COVID-19 vaccination drive for the Indian population in age group 18–45 years began April 2021 when seropositivity rates general were rising due to delta wave pandemic during April–May 2021. Between June 30, 2021, Jan 28, 2022, we enrolled 691 participants across four clinical sites India. In this non-randomised...
To determine the seroprevalence of SARS Cov 2 infection among vaccine naive population in a rural district South India post-second surge.We conducted cross-sectional study five villages randomly chosen sub-district Bangalore district. We did house to surveys and recruited 831 adults July 2021. tested samples for presence antibodies (including IgG & IgM) CoV-2 using Roche Elecsys SARS-CoV-2 -S assay that quantifies against receptor-binding domain (RBD) spike (S) protein.We estimated an...
Respiratory illness threatens the learning potential of hundreds millions children around world. We find in a human volunteer study involving three sites and 253 volunteers that respiratory droplets — size nature to potentially contain COVID-19, influenza, allergens other contaminants diminish number on exhalation by up 99% via “airway hygiene” administration nasal saline rich calcium. Exhaled particles were significantly higher efficacy airway hygiene greatest at site (Bangalore India) with...
Abstract Dirty air and poor access to healthcare threatens the lives of billions people in low-income regions world. We investigated whether upper-airway hydration might alter two-phase flow airways on normal tidal breathing be a useful, safe, easily distributed non-drug intervention for limiting risks COVID-19. In observational human volunteer studies involving 464 subjects Marburg, Germany (357 subjects), Boston, US (20 healthy Bangalore, India (87 recently tested positive COVID-19), we...
To determine the seroprevalence of SARS COV 2 among children in Bangalore Rural district.We conducted a cross-sectional study after second surge COVID-19 from 14 June to 13 July 2021 and recruited 412 through house visits four villages rural district. We administered questionnaire collect demographics details infection used ABCHEK Antibody Card test (NuLifecare,India) which is an ICMR approved for detecting antibodies (IgG & IgM) by immunochromatography using finger prick method. Statistical...
A BSTRACT Background: Scrub typhus, caused by Orientia tsutsugamushi , is a commonly occurring, but underdiagnosed rickettsial infection in India. Considering the high incidence of scrub typhus among patients with acute febrile illness hospital setting and paucity community seroprevalence studies, we aimed to estimate prevalence Bengaluru Rural District. Methods: pilot cross-sectional survey was conducted between October December 2022 eligible asymptomatic adults from five randomly selected...
Abstract Background There are limited global data on head-to-head comparisons of vaccine platforms assessing both humoral and cellular immune responses, stratified by pre-vaccination serostatus. The COVID-19 vaccination drive for the Indian population in 18 to 45-year age-group began April 2021 when seropositivity rates general were rising due Delta wave April-May 2021. Methods Between 30 June 28 January 2022, we enrolled 691 participants 18-45 age group across 4 clinical sites India. In...
Compared to nasopharyngeal/oropharyngeal swabs (N/OPS-VTM), non-invasive saliva samples have enormous potential for scalability and routine population screening of SARS-CoV-2. In this study, we investigate the efficacy relative N/OPS-VTM use as a direct source RT-PCR based SARS-CoV-2 detection.
Assessment of antibody response to vaccination against SARS CoV2 has clinical, public health, and policy implications during the pandemic in context future waves.In this repeated cross-sectional study, we estimated total binding levels spike protein virus post two doses Covishield vaccine among 133 health care workers (HCWs) (phase 1), followed by a subset (n = 61) group at 9 months after second dose 2). The time period first blood collection corresponds Delta Omicron waves, respectively.We...
Abstract Varicella infection during pregnancy has serious and/or difficult implications and in some cases lethal outcome. Though epidemiological studies developing countries reveal that a significant proportion of patients may remain susceptible pregnancy, such an estimate women is not known India. We designed this study to the prevalence factors associated with susceptibility varicella among rural urban pregnant South prospectively recruited 430 analysed their serum IgG antibodies as...
We aimed to study the rate of isoniazid (INH) resistance in Extrapulmonary Tuberculosis samples from a private care setting. A Line probe assay was performed on 74 culture isolates Mycobacterium tuberculosis or directly extrapulmonary received our laboratory 2018 2021. The INH mono-resistance among these 6.7%. (5 74) (95% CI: 1.04%-12.48%) Resistance rifampicin not detected. Increasing availability and leveraging public partnerships hospitals for universal testing may increase detection...
Abstract Purpose Compared to nasopharyngeal/oropharyngeal swabs, non-invasive saliva samples have enormous potential for scalability and routine population screening of SARS-CoV-2. In this study, we are investigating the efficacy relative swabs use as a direct source RT-PCR based SARS-CoV-2 detection. Methods Paired were collected from suspected positive patients tested using RT-PCR. Generalised linear models used investigate factors that explain result agreement. Further, simulations...
We conducted a serial cross-sectional study and used blood bank donors serosurvey the ICMR reports for comparison. Seroprevalence was 0% among HCWs (n-211) (n-210) during first phase while reported 0.5% general population in district at same time. In 2, we estimated seroprevalence of 9.2% as compared to 18.8% population. comparable that both phases. postulate good infection control policies practice can provide safe working environment without additional risk HCWs.
Abstract Background Despite rigorous disinfection, fumigation and air treatment, infectious microbial load has been found to circulate survive for significant durations in health care settings. This raises concerns hospital acquired infections. We have developed a novel, hybrid, trap- and-kill airborne-microbicidal technology called “ZeBox” which is efficient clearing 99.999% of airborne under controlled lab conditions. In this study we evaluate the clinical performance ZeBox reducing...
Abstract Dirty air and poor access to healthcare threatens the lives of billions people in low-income regions world. We investigated whether upper-airway hydration might alter two-phase flow airways on normal tidal breathing be a useful, safe, easily distributed non-drug intervention for limiting risks COVID-19. In observational human volunteer studies involving 464 subjects Marburg, Germany (357 subjects), Boston, US (20 healthy Bangalore, India (87 recently tested positive COVID-19), we...