A5065549764- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Genetic Associations and Epidemiology
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Advancements in Battery Materials
- Methane Hydrates and Related Phenomena
- Hepatitis C virus research
- Immunotherapy and Immune Responses
- Climate Change and Health Impacts
- Hydrocarbon exploration and reservoir analysis
- Medical Imaging Techniques and Applications
- Folate and B Vitamins Research
- CO2 Sequestration and Geologic Interactions
- Conducting polymers and applications
- Genetic Mapping and Diversity in Plants and Animals
- Air Quality and Health Impacts
- Bone and Joint Diseases
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Advanced Image Processing Techniques
- BRCA gene mutations in cancer
Zunyi Medical University
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2013-2024
University of California, Los Angeles
2020-2024
Beijing Institute of Technology
2024
Shandong University
2006-2024
Shandong University of Traditional Chinese Medicine
2024
South China University of Technology
2024
Beijing Anzhen Hospital
2023
Capital Medical University
2023
Oregon Health & Science University
2023
Importance Comorbidities and genetic correlations between gastrointestinal tract diseases psychiatric disorders have been widely reported, with the gut-brain axis (GBA) hypothesized as a potential biological basis. However, degree to which shared determinants are involved in these associations underlying GBA is unclear. Objective To investigate etiology identify genomic loci, genes, pathways. Design, Setting, Participants This genome-wide pleiotropic association study using summary...
The current genome-wide association study (GWAS) of Lewy body dementia (LBD) suffers from low power due to a limited sample size. In addition, the genetic determinants underlying LBD and shared etiology with Alzheimer's disease (AD) Parkinson's (PD) remain poorly understood.Using largest GWAS summary statistics date (2591 cases 4027 controls), late-onset AD (86,531 676,386 PD (33,674 449,056 we comprehensively investigated basis among LBD, AD, PD. We first conducted correlation analysis...
Conditional image generation plays a vital role in medical analysis as it is effective tasks such super-resolution, denoising, and inpainting, among others. Diffusion models have been shown to perform at state-of-the-art level natural generation, but they not thoroughly studied with specific conditions. Moreover, current their own problems, limiting usage various tasks. In this paper, we introduce the use of conditional Denoising Probabilistic Models (cDDPMs) for which achieve performance on several
To evaluate the value of whole-body magnetic resonance imaging (WBMRI) in diagnosing muscular and extra lesions patients with polymyositis (PM) dermatomyositis (DM).A retrospective analysis WBMRI data from PM/DM who met Bohan Peter diagnostic criteria was performed. X2 test used to compare rate positive diagnosis newly diagnosed using WBMRI, serum creatine kinase test, EMG. McNemar performance chest CT detecting interstitial lung disease (ILD).The study included 129 (30 PM cases 99 DM...
Mendelian randomization (MR) is a common tool for identifying causal risk factors underlying diseases. Here, we present method, MR with automated instrument determination (MRAID), effective analysis. MRAID borrows ideas from fine-mapping analysis to model an initial set of candidate single-nucleotide polymorphisms that are in potentially high linkage disequilibrium each other and automatically selects among them the suitable instruments inference. also explicitly models both uncorrelated...
Abstract Objectives To investigate the influence of patient's position on entry embolized air into systemic circulation after embolism (AE). Materials and methods 116 patients with AE were selected as study subjects, including 81 undergoing CT-guided transthoracic biopsy 35 localization pulmonary nodule before video-assisted thoracoscopic surgery. While maintaining original position, 94 out underwent at least one follow-up CT within 5 to 15 minutes AE. The following two situations considered...
Nanoporous gold freestanding films (NPG FSFs) have been fabricated via overgrowth of onto self-assembled monolayers nanocrystals at planar fluid–fluid interfaces. The resulting NPG FSFs are ligand-free on their surfaces and sizes can be as large several cm2. fairly mechanically robust; effective Young's moduli the order about 10 GPa. exhibit efficient electrocatalytic activity for methanol oxidation with an excellent electrochemical endurance, which is attributed to presence high-index...
Background This Mendelian randomization study aims to investigate causal associations between genetically predicted insomnia and 14 cardiovascular diseases (CVDs) as well the potential mediator role of 17 cardiometabolic risk factors. Methods Results Using genetic association estimates from large genome-wide studies UK Biobank, we performed a 2-sample analysis estimate with CVD conditions in primary analysis. Then mediation was conducted explore factors using network design. After correcting...
Diffusion models have achieved impressive performance on various image generation tasks, including super-resolution. Despite their performance, diffusion suffer from high computational costs due to the large number of denoising steps. In this paper, we proposed a novel accelerated model, termed Partial Models (PDMs), for magnetic resonance imaging (MRI) We observed that latents diffusing pair low- and high-resolution images gradually converge become indistinguishable after certain noise...
Prostate adenocarcinoma is one of the leading adult malignancies. Identification multiple causative biomarkers necessary and helpful for determining occurrence prognosis prostate adenocarcinoma. We aimed to identify potential prognostic genes in microenvironment estimate causal effects simultaneously. obtained gene expression data from TCGA project identified differentially expressed based on immune-stromal components. Among these genes, 68 were associated with biochemical recurrence at 3...
To compare the quantitative background parenchymal enhancement (BPE) in women with different lifetime risks and BRCA mutation status of breast cancer using screening MRI.