Siyi Zhu

ORCID: 0000-0001-8213-7622
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About
Contact & Profiles
Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • Bone health and osteoporosis research
  • Mobile Health and mHealth Applications
  • Total Knee Arthroplasty Outcomes
  • Long-Term Effects of COVID-19
  • Bone Metabolism and Diseases
  • Knee injuries and reconstruction techniques
  • Pharmacology and Obesity Treatment
  • Vitamin D Research Studies
  • Tendon Structure and Treatment
  • Electromagnetic Fields and Biological Effects
  • Diabetic Foot Ulcer Assessment and Management
  • Respiratory Support and Mechanisms
  • COVID-19 and Mental Health
  • Musculoskeletal pain and rehabilitation
  • Social Media in Health Education
  • Diet and metabolism studies
  • Diabetes Management and Education
  • Breast Cancer Treatment Studies
  • Phytochemical and Pharmacological Studies
  • Physical Activity and Health
  • Health Policy Implementation Science
  • Diverse Scientific Research in Ukraine
  • Airway Management and Intubation Techniques
  • Periodontal Regeneration and Treatments

Sichuan University
2016-2025

State Key Laboratory of Oral Diseases
2020-2025

West China Hospital of Sichuan University
2016-2024

Zhejiang University
2023-2024

Shanghai University of Medicine and Health Sciences
2024

Guangxi Medical University
2013-2024

Hunan Agricultural University
2024

First Affiliated Hospital of GuangXi Medical University
2013-2024

Ningbo University
2024

Shanghai Institute of Technology
2022-2024

Background Current guidelines emphasize an active lifestyle in the management of knee osteoarthritis (OA), but up to 90% patients with OA are inactive. In a previous study, we demonstrated that 8-week physiotherapist (PT)-led counseling intervention, use Fitbit, improved step count and quality life OA, compared control. Objective This study aimed examine effect 12-week, multifaceted wearable-based program on physical activity patient outcomes OA. Methods was randomized controlled trial...

10.2196/19116 article EN cc-by JMIR mhealth and uhealth 2020-07-03

Objective To estimate the prevalence of disability and anxiety in Covid-19 survivors at discharge from hospital analyze relative risk by exposures. Design Multi-center retrospective cohort study. Setting Twenty-eight hospitals located eight provinces China. Methods A total 432 with laboratory-confirmed SARS CoV-2 infection participated this At discharge, we assessed instrumental activities daily living (IADL) Lawton’s IADL scale, dependence (ADL) Barthel Index, Zung’s self-reported scale....

10.1371/journal.pone.0243883 article EN cc-by PLoS ONE 2020-12-17

Background An evidence-based eHealth education tool was developed for patients with knee osteoarthritis (KOA). This study aimed to evaluate the long-term effectiveness on patient knowledge level and analyzed patient's satisfaction proposed tool. Methods A two-arm randomized controlled trial performed, 218 KOA allocated 1:1 two groups by balanced block randomization. Both received usual care additionally, group used during process. The primary outcome measure validated questionnaire (PKQ-OA)....

10.1177/20552076251317230 article EN cc-by-nc-nd Digital Health 2025-01-01

We examined the effects of tumor necrosis factor-α (TNFα) and interleukin-6 (IL6) gene knockout in preserving bone loss induced by ovariectomy (OVX) mechanisms involved metabolism. Twenty female wild-type (WT), TNFα-knockout (TNFα-/-) or IL6-knockout (IL6-/-) mice aged 12 weeks were sham-operated (SHAM) subjected to OVX killed after 4 weeks. Bone mass skeletal microarchitecture determined using micro-CT. marrow stromal cells (BMSCs) from all three groups (WT, TNFα-/- IL6-/-) differentiate...

10.1530/jme-17-0218 article EN Journal of Molecular Endocrinology 2018-01-17

Knee osteoarthritis (KOA) is the most common degenerative joint disease in China, causing a huge economic burden on patients, families, and society. Standardized KOA rehabilitation treatment an important means to prevent treat promote development of high-quality medical services. This guideline updated basis 2016 2019 editions.Clinical questions regarding assessment were selected through clinical screening deconstruction, multiple rounds Delphi questionnaire consultation. The International...

10.1111/jebm.12555 article EN cc-by-nc-nd Journal of Evidence-Based Medicine 2023-09-01

We introduce UbiPhysio, a milestone framework that delivers fine-grained action description and feedback in natural language to support people's daily functioning, fitness, rehabilitation activities. This expert-like capability assists users properly executing actions maintaining engagement remote fitness programs. Specifically, the proposed UbiPhysio comprises descriptor knowledge retrieval-enhanced module. The translates data, represented by set of biomechanical movement features we...

10.1145/3643552 article EN other-oa Proceedings of the ACM on Interactive Mobile Wearable and Ubiquitous Technologies 2024-03-06

Previous studies have revealed that the japonica/indica hybrid rice has a higher yield potential, biomass production, and nitrogen (N) accumulation than japonica in China, however, at single N application rate. It remains unclear whether it also occurs or lower rate under same field condition. To investigate effects of rates on grain yield, uptake, dry matter accumulation, agronomic use efficiency, experiments were conducted Jinhua City, Zhejiang Province during three consecutive growth...

10.3390/agronomy10020171 article EN cc-by Agronomy 2020-01-25

To analyze the risk factors associated with intubated critically ill patients in emergency department (ED) and develop a prediction model by machine learning algorithms.

10.1002/emp2.13190 article EN cc-by-nc-nd Journal of the American College of Emergency Physicians Open 2024-05-31

Pulsed electromagnetic fields (PEMFs) show promise as a treatment for knee osteoarthritis (KOA) by reducing inflammation and promoting chondrogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs).

10.1186/s12967-024-05470-7 article EN cc-by-nc-nd Journal of Translational Medicine 2024-08-06

Abstract Osteoporosis is a metabolic bone disease that affects hundreds of millions people worldwide and characterized by excessive loss protein mineral content. The incidence mortality osteoporosis increase with age, creating significant medical economic burden globally. importance cholesterol levels has been reported in the development diseases including osteoporosis. It important to note key enzymes molecules involved homeostasis are closely related formation. Excessive may cause...

10.1042/cs20220752 article EN Clinical Science 2023-08-01
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