A5043102062- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Infective Endocarditis Diagnosis and Management
- RNA modifications and cancer
- Breast Cancer Treatment Studies
- Ferroptosis and cancer prognosis
- Pericarditis and Cardiac Tamponade
- Liver Disease and Transplantation
- Clinical Nutrition and Gastroenterology
- Alcohol Consumption and Health Effects
- Sleep and related disorders
- Breast Implant and Reconstruction
- Myasthenia Gravis and Thymoma
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Intensive Care Unit Cognitive Disorders
- Inflammatory mediators and NSAID effects
- Pancreatic and Hepatic Oncology Research
- Endometrial and Cervical Cancer Treatments
- Medical Research and Treatments
- Posttraumatic Stress Disorder Research
- Breast Lesions and Carcinomas
The People's Hospital of Guangxi Zhuang Autonomous Region
2009-2024
University of Jinan
2024
Jinan University
2024
Academy of Medical Sciences
2021-2023
Southern Medical University
2016-2023
Shanghai Research Institute of Building Sciences (China)
2023
Chinese University of Hong Kong
2021
Guangxi Academy of Sciences
2021
Sichuan University
2021
West China Hospital of Sichuan University
2021
Background As effective medication to treat COVID-19 is currently unavailable, preventive remedies may be particularly important.
Background: Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide. A major cause for failure cancer therapy development chemoresistance. Although progress has been made in study mechanisms underlying cells resistance, little known about role microRNAs (miRNAs) resistance. Methods and Results: Fifteen miRNAs, including 6 up-regulated miRNAs (> 2.0-fold) 9 down-regulated (< 0.5-fold) were differentially expressed 5-fluorouracil-resistant their parental...
Pre-hospitalisation, hospitalisation and post-hospitalisation factors may significantly affect depression, anxiety post-traumatic growth (PTG) among COVID-19 survivors. Our study investigated PTG their correlates A cross-sectional telephone survey recruited 199 patients (Mean age = 42.7; 53.3% females) at six-month follow-up after hospital discharge in five Chinese cities (i.e. Wuhan, Shenzhen, Zhuhai, Dongguan Nanning). Their demographic information, clinical records experiences during...
Objective To estimate the prevalence of disability and anxiety in Covid-19 survivors at discharge from hospital analyze relative risk by exposures. Design Multi-center retrospective cohort study. Setting Twenty-eight hospitals located eight provinces China. Methods A total 432 with laboratory-confirmed SARS CoV-2 infection participated this At discharge, we assessed instrumental activities daily living (IADL) Lawton’s IADL scale, dependence (ADL) Barthel Index, Zung’s self-reported scale....
COVID-19 survivors who had acute respiratory symptoms might experience prolonged post-traumatic stress disorder (PTSD) due to further rehabilitation, somatic and related distress. The conservation of resource (COR) theory is a well-developed understand how people develop PTSD in traumatic events. current study aimed examine the potential factors interrelationships among this based on COR theory. This cross-sectional telephone survey enrolled 199 patients (Mean age = 42.7; 53.3% females) 6...
The associations between metabolic dysfunction-associated fatty liver disease (MAFLD) and cancer development, especially extrahepatic cancers, are unknown. aims of the current study were to investigate incidence rates MAFLD analyze development cancers.This historical cohort included participants who underwent ultrasonographic detection hepatic steatosis at a tertiary hospital in China from January 2013 October 2021. was diagnosed accordance with International Expert Consensus Statement. Cox...
Abstract Sleep disturbances are among the most prevalent neuropsychiatric symptoms in individuals who have recovered from severe acute respiratory syndrome coronavirus 2 infections. Previous studies demonstrated abnormal brain structures patients with sleep disease 2019 (COVID-19). However, neuroimaging on caused by COVID-19 scarce, and existing primarily focused long-term effects of virus, minimal phase data. As a result, little is known about pathophysiology COVID-19. To address this...
Background As a highly infectious disease with human-to-human transmission characteristics, COVID-19 has caused panic in the general public. Those who have recovered from may experience discrimination and internalized stigma. They be more likely to worry about social interaction develop anxiety.Objectives This study investigated associations among hospitalization factors, social/interpersonal personal anxiety reveal mechanism of survivors.Methods A cross-sectional, multicenter telephone...
Objective The Guizhi Fuling (GZFL) capsule has been a traditional Chinese medicine for the treatment of gynecological inflammation past thousands years. However, as formula, its therapeutic mechanism not clearly elucidated. aim this study is to investigate role apoptosis during GZFL therapy endometrial hyperplasia.Methods rat model endometriosis was established, and rats were given different doses capsule. Uterine histomorphometric analysis, real-time quantitative PCR (qPCR) Western blotting...
Understanding factors associated with post-discharge sleep quality among COVID-19 survivors is important for intervention development.This study investigated and its correlates patients 6 months after their most recent hospital discharge.Healthcare providers at hospitals located in five different Chinese cities contacted adult discharged between 1 February 30 March 2020. A total of 199 eligible provided verbal informed consent completed the interview. Using score on single-item Sleep Quality...
SIVA-1 has been shown to affect apoptotic processes in various different cell lines, and significantly contributes the decreased responsiveness of cancer cells some chemotherapy agents. However, whether potential application gastric remains unknown. Therefore, objective this investigation was clarify distinct function chemotherapeutic drug resistance within a living murine model with malignancy, initially elucidate underlying mechanisms. In an established multidrug-resistant xenograft mouse...
Abstract Pulmonary fibrosis is a devastating disease, and the pathogenesis of this disease not completely clear. Here, medical records 85 Covid-19 cases were collected, among which progression analyzed in detail. Next, data independent acquisition (DIA) quantification proteomics untargeted metabolomics used to screen disease-related signaling pathways through clustering enrichment analysis differential expression proteins metabolites. The main imaging features lesions located bilateral lower...
We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery.This was a retrospective study patients and surgery undergoing cardiac between January 2006 November 2022 at our hospital.Eight hundred thirty-two were divided into group (n = 112) without 720). There 48 operative deaths (5.4%). Univariate multivariate analyses showed that is statistically significantly associated in-hospital mortality following prolonged...
Aims Pyruvate kinase M 2 ( PKM 2) and lactate dehydrogenase 5 LDH 5) are two metabolic oncogenic markers of cancer. In this study, we sought to investigate their expression patterns prognostic value in tongue squamous cell carcinoma TSCC ). Methods results The subcellular localization lines were determined by W estern blot immunofluorescence. abundance was examined immunohistochemistry 63 tumour specimens; association with multiple clinicopathological parameters overall patient survival...
Objectives To evaluate the results of inoperable and operable with aortic valve endocarditis, focus on risk factors, significance, management destruction annulus in endocarditis. Methods The retrospective study was completed to investigate patients endocarditis undergoing cardiac surgery between January 2006 November 2022 at our hospital. Results 512 were divided into group ( n = 80) without 432). There 32 operative deaths (6.3%, 32/512). By univariate multivariate analysis, is found be...
The inhibitory roles of limonin have been revealed in various tumors. However, the and related mechanism hepatocellular carcinoma (HCC) progression are still confused. Here, we collected non-adherent spheroids formed by HCC cells found that proportion G0 phase was remarkably higher than cells. Additionally, increased EdU incorporation without affecting apoptosis spheroids. Notably, upon treatment, decreased S/G2/M increased. Furthermore, attenuated stemness cells, characterized as ALDH1...
Tea polyphenols (TP) are the major ingredients in tea beverages that display health-benefits including anti-oxidation, anti-inflammation, anti-aging, attenuating blood pressure and deflating. In this study, we investigated neuroprotective effects of TP to attenuate staurosporine (STS)-induced cytotoxicity. Rat hippocampal neurons were isolated, cultured incubated with STS induce neurite collapse apoptosis, however, medication eliminated these adverse maintained morphology neurons. decreased...
Background The association between metabolic dysfunction–associated fatty liver disease (MAFLD) and chronic kidney (CKD) is unclear. Objective This longitudinal cohort study aimed to test whether MAFLD plays an important role in the development of CKD. Methods included 41,246 participants who had undergone 3 or more health examinations from 2008 2015 at People’s Hospital Guangxi Zhuang Autonomous Region, China. Participants were categorized into 2 groups according they presented with without...
Hepatocellular carcinoma (HCC) is regarded as a leading cause of cancer-related deaths, and its progression associated with hypoxia the induction hypoxia-inducible factor (HIF). Meloxicam, selective cyclooxygenase-2 (COX-2) inhibitor, induces cell death in various malignancies. However, underlying mechanism remains to be elucidated HCC, especially under hypoxic conditions. The alteration COX-2 HIF-1 α oncogenicity was evaluated HCC specimens by tissue microarray. Cell viability, angiogenesis...