A5062826091- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Microbial infections and disease research
- Syphilis Diagnosis and Treatment
- Urinary Tract Infections Management
- Blood groups and transfusion
- Sex work and related issues
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Reproductive System and Pregnancy
- Hidradenitis Suppurativa and Treatments
- Maternal and fetal healthcare
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Bacterial Identification and Susceptibility Testing
- HIV, Drug Use, Sexual Risk
- Gastrointestinal motility and disorders
- Clinical practice guidelines implementation
- Hepatitis C virus research
- Autoimmune and Inflammatory Disorders
- Inflammatory Bowel Disease
- Human Health and Disease
- Adolescent Sexual and Reproductive Health
- Gastroesophageal reflux and treatments
- Sexuality, Behavior, and Technology
Central Research Institute of Epidemiology
2014-2020
Pirogov Russian National Research Medical University
2017
University Hospital Frankfurt
2017
Goethe University Frankfurt
2017
Abstract Background & Aims Acute‐on‐chronic liver failure ( ACLF ) is characterized by an acute deterioration of function in patients with cirrhosis combination recently defined organ failures. Our aim was to independently validate the prognostic value established EASL ‐ CLIF ‐Consortium definition and identify new predictors short‐term mortality. Methods Patients International Classification Diseases, Tenth Revision diagnosis (sub)acute were retrospectively categorized according...
Azithromycin has been widely used for Mycoplasma genitalium treatment internationally. However, the eradication efficacy substantially declined recent decade. In Russia, josamycin (another macrolide) is recommended first-line M. infections, however, no data regarding with and resistance in infections have internationally published. We examined prevalence males attending an STI clinic Moscow, Russia from December 2006 to January 2008, investigated male urethritis, monitored DNA dynamics...
In this study, we performed an evaluation of the new CE ‐marked multiplex real‐time AmpliSens N.gonorrhoeae/C.trachomatis/M.genitalium/T.vaginalis‐ MULTIPRIME ‐ FRT PCR assay compared to APTIMA tests, i.e., COMBO 2 assay, Trichomonas vaginalis ( FDA ‐approved), and two different Mycoplasma genitalium assays (research use only; one them only used for discrepancy analysis). Vaginal swabs (n = 209) first‐void urine FVU ) specimens from females 498) males 554), consecutive attendees 1261) at a...
Background and objective Resistance in the sexually transmitted bacterium Mycoplasma genitalium to all recommended therapeutic antimicrobials have rapidly emerged. However, date, internationally reported resistance surveillance data for M. strains circulating Eastern Europe are entirely lacking. The aim of this study was estimate prevalence macrolide fluoroquinolone resistance-associated mutations four cities Russia one Estonia, 2013–2016. Materials methods Consecutive urogenital samples...
The aim of the study was to evaluate diagnostic value Nugent score, wet mount microscopy, and polymerase chain reaction (PCR) test developed in Russia for bacterial vaginosis (BV) diagnosis.One hundred Caucasian women were enrolled this study. Three vaginal samples taken from each participant: 1 PCR analysis, score evaluation, microscopy. smears microscopy air-dried sent Femicare, Tienen, Belgium, blinded analysis by Multiplex real-time performed using primers probes targeting Gardnerella...
Traditional microscopy-based methods for diagnosis of bacterial vaginosis (BV) are underutilized in many settings, and molecular techniques may provide opportunities rapid, objective, accurate BV diagnosis. This study evaluated the quantitative AmpliSens Florocenosis/Bacterial vaginosis-FRT multiplex real-time PCR (Florocenosis-BV) assay. Vaginal samples from a previous including unselected female subjects (n = 163) using Amsel criteria 454 pyrosequencing were examined with Florocenosis-BV...
To estimate the prevalence and factors associated with HIV five other STIs among outdoor female sex workers (OSFW) indoor FSW (IFSW). Methods Cross-sectional survey using respondent-driven sampling methodology. Participants answered a bio-behavioural questionnaire were tested for Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Trichomonas vaginalis (TV), syphilis (lifetime contact) Mycoplasma genitalium (MG). Weighted 95% CIs calculated. multivariate logistic regression was performed...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
41 women with polycystic ovary syndrome (PCOS) and 15 healthy of reproductive age were examined to evaluate ovarian aromatase activity. Aromatase activity was determined by the decrease estradiol level after peroral intake inhibitor letrosol. To examine antral follicle (∆E2) divided on blood antimullerian hormone (AMH), which is corresponded number follicles. Significant variations follicles in patients PCOS determined: 34.1 % it within physiological ranges, 48.8 decreased 17.1 increased....
Abstract Extraintestinal symptoms of Crohn's disease may occur in the eye, urinary system, on skin, or subcutaneous fat. We report case a 7‐year diagnostic search isolated vulvar 47‐year‐old woman. The is characterized by gradual formation pronounced bilateral asymmetric labial hypertrophy.
The efficacy and safety of laktagel in the treatment bacterial vaginosis was studied. Two components proved more effective treatments based on use metronidazole ornidazole with lactic acid, compared monotherapy group 5-nitroimidazole. combined local acid is a safe method to achieve high efficiency reduce frequency relapses separated BV period. complex therapy examination algorithm patients various age presented.
Background: Placental insufficiency is a major problem of modern obstetrics due to its link maternal and perinatal morbidity mortality.Placental microcirculatory disorders play decisive role in the pathogenesis this condition.Thus, an evaluation placental blood flow particular importance crucial for appropriate diagnosis.The aim study was evaluate patients with insufficiency.SMI (superb microvascular imaging) compared color Doppler that purpose.Materials Methods: Primigravida (n=91) at 15 16...
Оригинальные исследОванияКАН -короткоаксонные нейроны ОЛ -обонятельная луковица тальные данные о распределении NO-позитивных структур в различных слоях обонятельных луковиц крыс, не учитываются возрастные особенности, что затрудняет оценку направленности компенсаторноприспособительных реакций при экспериментальных воздействиях.Целью исследования является установление возрастных показателей активности n-NOS позитивных субпопуляциях нейронов обонятельной луковицы у интактных крыс
The article provides a brief literature review of the definitions "sphincters digestive system.” authors discuss various morphological data gastrointestinal sphincters in connection structure, function and organization their innervation. presents different about terminology, classifications innervation sphincter apparatus gastro-intestinal tract. Particular attention is paid to role own pacemaker interstitial cells Cajal (the organizers peristalsis).
Das akut-auf-chronische Leberversagen (ACLV) ist charakterisiert durch eine akute Verschlechterung der Leberfunktion bei Patienten mit chronischer Lebererkrankung (i.d.R. Zirrhose) einhergehend hepatischem u./o. extrahepatischem Organversagen. ACLV entsteht typische Auslöser, wie Infektionen oder übermäßiger Alkoholkonsum, die fulminante systemische Entzündungsreaktion triggern können.
Aim . To evaluate the effectiveness of PCR tests to diagnose common pathological conditions associated with vaginal discharge (i.e. bacterial vaginosis, aerobic vaginitis, and vulvovaginal candidiasis) in patients without complaints. Materials Methods The study enrolled 240 women which flled out an original questionnaire on demographic, social, behavioral, reproductive features underwent a examination. Real-time smears was used detect candidiasis, sexually transmitted infections (Chlamydia...