- Atrial Fibrillation Management and Outcomes
- Antibiotic Resistance in Bacteria
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cardiac Arrhythmias and Treatments
- RNA modifications and cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Bacterial biofilms and quorum sensing
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Dietary Effects on Health
- Cardiovascular Disease and Adiposity
- Helicobacter pylori-related gastroenterology studies
- Vibrio bacteria research studies
- Liver Disease and Transplantation
- Regulation of Appetite and Obesity
- Complement system in diseases
- Nitric Oxide and Endothelin Effects
- Bacterial Genetics and Biotechnology
- Genetic Associations and Epidemiology
- Cancer-related molecular mechanisms research
- Bacteriophages and microbial interactions
- Cardiomyopathy and Myosin Studies
- Burkholderia infections and melioidosis
- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
Guangzhou University of Chinese Medicine
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Peking Union Medical College Hospital
2023
Chinese University of Hong Kong
2014
Beijing Anzhen Hospital
2013
Capital Medical University
2013
Nanjing Medical University
2006
Jiangsu Province Hospital
2006
is an opportunistic pathogen that causes acute and chronic infections in immunocompromised individuals. Small regulatory RNAs (sRNAs) regulate multiple bacterial adaptations to environmental changes, especially virulence. Our previous study showed sRNA PrrH negatively regulates the expression of a number virulence factors, such as pyocyanin, rhamnolipid, biofilm, elastase
Several epidemiological studies have shown that the myeloperoxidase ( MPO ) G–463A polymorphism may influence risk of many cancers, including lung, breast, bladder and laryngeal cancer. However, there is no study concerning gastric cancer risk. In this hospital-based, case–control study, we used polymerase chain reaction–restriction fragment length protocols to examine prevalence in A significantly different distribution –463G/A genotype was demonstrated among cases controls (χ 2 = 7.42, P...
Metabolic disorders including type 2 diabetes, obesity and hypertension have growing prevalence globally every year. Genome-wide association studies successfully identified many genetic markers associated to these diseases, but few studied their interaction effects. In this study, twenty candidate SNPs from sixteen genes are selected, a lasso-multiple regression approach is implemented consider the SNP–SNP interactions among them in an Asian population. It found out that main effects of weak...
Plasmid-mediated conjugation is a common mechanism for most bacteria to transfer antibiotic resistance genes (ARGs). The conjugative of ARGs emerging as major threat human beings. Although several transfer-related factors are known regulate this process, small RNAs (sRNAs)-based regulatory roles remain be clarified. Here, the Hfq-binding sRNA GadY in donor strain Escherichia coli ( E. ) SM10λπ was identified new regulator bacterial conjugation. Two models established our previous studies...
The incidence of type 2 diabetes in China has exhibited an increasing trend, including younger individuals, over the past years. Early-onset (EOT2D) refers to diagnosed before 40 years age. These patients have poor metabolic control and are highly susceptible diabetic complications, which poses challenges for treatment. However, few studies reported on treatment EOT2D. We determined clinical features trends drug use with mellitus (T2DM).
Purpose: Atrial fibrillation (AF) is common in patients with hypertrophic cardiomyopathy (HCM) and known to predict adverse outcome. Radiofrequency catheter ablation represents a promising option improve symptoms outcome of these patients. The purpose this study was evaluate the long term effects AF HCM. Methods: Twenty-five consecutive (19 male, age 53.4±8.0 years) HCM undergoing pulmonary vein (PV) isolation or without additional left atrial roof, mitral isthmus cavotricuspid linear...
Objectives: This study explored the relationship between weight control and atrial fibrillation (AF) recurrence after catheter ablation in overweight obese patients. Methods: We prospectively enrolled consecutive 333 patients aged 28 to 87 years old, who underwent for AF Beijing Anzhen Hospital October 2015 February 2016. Data of patients' characteristics, laboratory examination treatment were collected at baseline. Each patient was followed up 3, 6 12 months collect information on weight,...