- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Advanced X-ray and CT Imaging
- Acute Ischemic Stroke Management
- Ultrasound and Hyperthermia Applications
- Radiation Dose and Imaging
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Tuberculosis Research and Epidemiology
- Digital Radiography and Breast Imaging
- AI in cancer detection
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- RNA Interference and Gene Delivery
- Cardiovascular Function and Risk Factors
- Aortic Thrombus and Embolism
- Pulmonary Hypertension Research and Treatments
- Heart Rate Variability and Autonomic Control
- Virus-based gene therapy research
- Cardiac Valve Diseases and Treatments
- Diagnosis and treatment of tuberculosis
- Aortic aneurysm repair treatments
- Photoacoustic and Ultrasonic Imaging
- Electrospun Nanofibers in Biomedical Applications
Capital Medical University
2014-2024
National Clinical Research Center for Digestive Diseases
2023-2024
Beijing Anzhen Hospital
2011-2024
National Clinical Research
2023
Chinese Center For Disease Control and Prevention
2014-2022
Center for Disease Control
2020
Ningbo Dahongying University
2018-2019
Center for Tuberculosis Control of Guangdong Province
2016
George Institute for Global Health
2011-2016
Shanghai Sixth People's Hospital
2015
Background and Purpose— Early diagnosis of cerebral venous thrombosis (CVT) is currently a major clinical challenge. We proposed novel magnetic resonance black-blood thrombus imaging technique (MRBTI) for detection quantification CVT. Methods— MRBTI was performed on 23 patients with proven CVT 24 negative confirmed by conventional techniques. Patients were divided into 2 groups based the duration onset: ≤7 days (group 1) between 7 30 2). Signal/noise ratio calculated detected thrombus,...
<h3>Abstract</h3> <b>Objective:</b> To examine the risk of stroke in relation to quality hypertension control routine general practice across an entire health district. <b>Design:</b> Population based matched case-control study. <b>Setting:</b> East Lancashire Health District with a participating population 388 821 aged (80. <b>Subjects:</b> Cases were patients under 80 their first identified from register between 1 July 1994 and 30 June 1995. For each case two controls for age sex selected...
64-MDCT Coronary Angiography: Phantom Study of Effects Vascular Attenuation on Detection StenosisXiaolu Fei1, Xiangying Du1, Qi Yang1, Yun Shen2, Pengyu Li1, Jingmin Liao2 and Kuncheng Li1Audio Available | Share
Abstract The aim was to investigate the effects of echo time (TE) on diffusion quantification brain white matter. Seven rhesus monkeys (all males; age, 4–6 years; weight, 5–7 kg) underwent tensor imaging (DTI) with a series TEs in 1.5T and 3.0T MR scanners. mean diffusivity (MD), fractional anisotropy (FA), primary (λ 1 ), transverse eigenvalues 23 ) were measured region interest at bilateral internal capsule. Pearson correlation showed that FA λ increased decreased TE both except for MD....
Tuberculosis (TB) surveillance in China is organized through a nationwide network of about 3200 hospitals and health facilities. In 2005, an electronic Information Management System (TBIMS) started to be phased replace paper recording. The TBIMS collects key information on TB cases notified care facilities, exchanges real-time data with the Infectious Disease Reporting System, which covers country's 37 notifiable diseases. system accessible authorized users at every level password-protected...
Whole-heart coronary magnetic resonance angiography (MRA) is a promising method for noninvasive, radiation-free detection and exclusion of obstructive artery disease; however, the required imaging time robustness technique are not yet satisfactory. We evaluated value whole-heart MRA at 3.0T using 32-channel cardiac coil, which reduces image-acquisition times hence allows to increase clinical throughput.A total 110 consecutive patients with suspected disease referred clinically indicated...
Abstract Gadolinium diethylenetriamine pentaacetic acid (Gd‐DTPA) was encapsulated into biodegradable, bioadhesive polymeric microparticles to enable noninvasive monitoring of their local intravesical delivery with MRI. The were characterized by contrast agent encapsulation and release kinetics, T 1 relaxation rates, enhancement in vivo. level Gd‐DTPA loading 14.3 ± 0.6 μg/mg polymer. measured rates the showed a direct dependence on Gd‐DPTA content. Both 1.5T 4.7T MR scanners used image...
Background Atherosclerosis of brain- and heart-supplying arteries (BHAs) are risk indicators for patients with ischemic stroke, but the atherosclerosis burden (AB) intracranial, cervical, aortic, coronary in each total have not been simultaneously evaluated, associations vascular remain unknown. Methods Results With computed tomography angiography, single-territory AB was triple ranked on basis number arterial segments a significant atherosclerotic lesion. The (TAB) BHAs territories lesion,...
Aim . To investigate the clinical relevance of plaque’s morphological characteristics and distribution pattern using 3.0 T high-resolution magnetic resonance imaging (HRMRI) in patients with moderate or severe basilar artery (BA) atherosclerosis stenosis. Materials Methods Fifty-seven (33 symptomatic 24 asymptomatic patients) were recruited for HRMRI scan; all them had >50% stenosis on BA. The intraplaque hemorrhage (IPH), contrast-enhancement pattern, BA plaques compared between groups....
To evaluate the prevalence and risk of diabetes based on family history in high-risk subjects also to insulin sensitivity secretion these subjects.Data were analysed from 9756 participants Shanghai High-Risk Diabetic Screen (SHiDS) Project. Family was classified according parental sibling status. The odds ratios calculated for each grouping after adjusting other factors. Insulin resistance evaluated using oral glucose tolerance test-derived indices that validated by...
Nighttime blood pressure (BP) generally dips by 10% to 20% of the daytime values, and abnormal BP dipping may affect vascular health independently level. The regulation involves arterial baroreflex, whose receptors mainly reside in carotid sinuses aortic arch. Atherosclerosis these baroreceptor-resident arteries (BRAs) is frequent among patients with ischemic stroke (IS) might impair their BP-regulating capacity. We aimed examine associations between atherosclerosis BRA IS. ratio was...
Chronic obstructive pulmonary disease (COPD) is often associated with changes of the structure and function right ventricle (RV). Therefore, assessment ventricular myocardial mass (MM) clinically important for evaluation severity COPD, which may provide an objective basis therapeutic strategy.To assess RV MM in patients mild to severe COPD using magnetic resonance imaging (MRI).We prospectively studied 49 determined by test (PFT). Using Global Initiative classification, were divided into...
Abstract Of the various techniques employed to quantify temperature changes by MR, proton resonance frequency (PRF) shift‐based phase‐difference imaging (PDI) is most accurate and widely used. However, PDI associated with artifacts. Motivated these limitations, we developed a new method monitor MRI using balanced steady‐state free precession (balanced‐SSFP) pulse sequence. Magnitude images obtained SSFP sequence were used find PRF shift, which proportional change. Spatiotemporal maps...
This study was designed to evaluate the value of contrast-enhanced whole-heart coronary MRA (CMRA) at 3.0T in depicting cardiac venous anatomy. In resynchronization therapy (CRT), left ventricular (LV) pacing is achieved by positioning LV lead one tributaries sinus (CS). Pre-implantation knowledge anatomy may help determine whether transvenous placement for CRT feasible. Images 51 subjects undergoing CMRA were retrospectively analyzed. Data acquisition performed using...
To assess the 2012 served available market for tuberculosis (TB) diagnostics in China sector by Centre Disease Control and Prevention (CDC) hospital China, including both designated TB hospitals general hospitals.Test volumes unit costs were assessed tuberculin skin tests, interferon-gamma release assays (IGRAs), smear microscopy, serology, cultures, speciation nucleic-acid amplification tests (NAATs), drug susceptibility adenosine-deaminase (ADA). Data obtained from electronic databases...
To evaluate the feasibility of radiofrequency (RF)-enhanced vascular gene transduction and expression by using a magnetic resonance (MR) imaging-heating guidewire as an intravascular heating vehicle during MR imaging-guided therapy.The institutional committee for animal care use approved experimental protocol. The study included in vitro evaluation RF energy to enhance cells, well vivo validation RF-enhanced pig arteries. For experiments, approximately 10(4) smooth muscle cells were seeded...
Coronary artery stenosis (CAS) ≥ 50% frequently coexists in patients with acute ischemic cerebrovascular disease (AICVD), which portends unfavorable outcomes. We sought to examine whether AICVD CAS had more severe and diffused cervicocephalic atherosclerosis (CA).Patients were consecutively enrolled underwent simultaneous computed tomography angiography (CTA) of the coronary arteries. A total 140 divided into "AICVD+CAS" "AICVD only" groups according CTA showed at least one arterial segment....
Abstract Patients with ischemic cerebrovascular disease (ICVD) frequently develop concomitant peripheral artery (PAD) or renal stenosis (RAS), and multiterritorial atherosclerotic patients usually have a worse prognosis. We aimed to evaluate the status of atherosclerosis (AS) cervicocephalic AS (CAS) in ICVD AS, their correlation, related risk factors contributing coexisting cervicocephalic-peripheral (CPAS). Based on severity extent evaluated by computed tomography angiography ultrasound,...