Ultraviolet (UV) B radiation can cause skin aging by increasing matrix metalloproteinase (MMP) production and collagen degradation, leading to the formation of wrinkles. This study investigated whether hawthorn polyphenol extract (HPE) protects against UVB-induced photoaging using HaCaT human keratinocytes, normal dermal fibroblasts (HDFs), mice. Analysis phenol composition HPE high-performance liquid chromatography-mass spectrometry showed that chlorogenic acid (13.5%), procyanidin B2...

Exercise fatigue can exert deleterious effects on the body. This study evaluated and mechanisms by which Lonicera caerulea berry polyphenols extract (LCBP) improved treadmill endurance of mice. Comparison was performed between at 25°C low temperatures (-5°C). Energy storage, product metabolism, other biochemical indices were determined using vitamin C (VC) as a positive control. Co-immunoprecipitation to detect interaction different proteins. Dietary supplementation with LCBP significantly...

Chestnut is popular worldwide for its unique flavor, high eating quality and nutrition. Here, we evaluated the influence of phosphorylation acetylation on structural, physicochemical functional properties chestnut starch. Scanning electron micrographs showed agglomeration starch granules appearance numerous dents granule surface under acetylation. X-ray diffractograms confirmed that modification treatments did not affect C-type crystal pattern, but reduced relative crystallinity starch,...

This study aimed to determine the anti-obesity effects and mechanisms of Cerasus humilis polyphenol (CHP) in C57BL/6 obese mice 3T3-L1 cells. High-performance liquid chromatography–electrospray ionization-tandem mass spectrometry was used for qualitative quantitative identification CHP components. The mice, induced by feeding high-fat diet (HFD), were treated with (250 mg/kg/day) gavage 12 weeks. Orlistat gavaged at 15.6 mg/kg bw/day, as a positive control group. analysis revealed that main...

Dietary fiber can be fermented and utilized by gut microbiota to reshape the microbiota, thereby alleviating constipation. This experiment mainly studied physicochemical functions of hawthorn soluble dietary (HSDF)and its effect mechanism in constipation mice. Forty-five mice were divided into blank control group C, model M, positive HS group, low-dose LHSDF (1 g/kg/bw), high-dose HHSDF (2 g/kg/bw). The modeled at a dose 10 mg/kg/bw loperamide hydrochloride for 7 days, while remaining groups...

This study prepared hawthorn polyphenol microcapsules (HPM) by microencapsulation and revealed that its potential mechanism of action in fatigued mice involves regulation AMPK signaling pathway balancing the intestinal microflora. Spray drying process improved thermal stability polyphenol. After HPM treatment, weight-bearing swimming ability was significantly (p < 0.05). can effectively improve skeletal muscle substrate consumption product metabolism enhance antioxidant capacity 0.05 or p...

Chinese chestnut shell is a by-product of food processing and rich in polyphenols. This study sought to investigate the effect polyphenol extract (CSP) on weight loss lipid reduction 12-week high-fat diet (HFD)-induced murine obesity model. CSP (300 mg per kg body weight) was administered intragastrically daily. AG490, JAK2 protein tyrosine kinase inhibitor, also intraperitoneally injected. The results showed that an HFD induced leptin resistance (LR). Compared corresponding values group,...

Lonicera caerulea berry polyphenols (LCBP) are known to reduce cholesterol accumulation. Currently, it is unknown whether LCBP can activate Sirtuin 1 (SIRT1) regulate the formation of RAW264.7 macrophage foam cells. In this study, effect on lipid accumulation in macrophages was evaluated. Fluorescently labeled ox-LDL and 25-NBD were used detect uptake outflow rate from macrophages. Gene silencing performed using siRNA changes expression ATP-binding cassette transporter A1 (ABCA1), sterol...

Diabetic retinopathy is a major complication in patients with diabetes. Herein, we investigate how hawthorn polyphenol extract (HPE) affects high glucose-induced oxidation, inflammation, and apoptosis ARPE-19 cells. HPLC-MS/MS was used to determine HPE content composition. Reactive oxygen species (ROS) production assessed using fluorescence microscopy, while gene protein expressions were analyzed real-time PCR western blotting cells transfected miR-34a mimics. We found that treating 10 μg/ml...

This study investigated the effect of a hawthorn polyphenol extract (HPE) on ultraviolet B (UVB)-induced damage in HaCaT cells and mice. High-performance liquid chromatography/electrospray ionization tandem mass spectrometry was used to analyze phenolic composition HPE. The protective effects HPE its main components were compared cells. An enzyme-linked immunosorbent assay detect DNA (8-hydroxydeoxyguanosine levels). Flow cytometry western blotting measure extent apoptosis levels...

Summary Chestnut rice wine, also called banli mijiu (BLMJ), uses Chinese chestnut ( Castanea mollissima Blume) in the fermentation of traditional glutinous wine. This study characterised microbial communities and volatile compounds BLMJ explored their correlations. Headspace solid‐phase microextraction‐gas chromatography–mass spectrometry (HS‐SPME‐GC–MS) revealed that major during include eighteen important (OAV &gt; 1). High‐throughput sequencing (HTS) demonstrated abundance diversity...

This study aims to obtain the physicochemical properties of hawthorn fruit powder produced using different methods. Two drying methods, hot-air and freeze-drying, three grinding mortar grinding, shear pulverization, jet milling, were applied powders. The six powders compared scanning electron microscopy, X-ray diffraction (XRD) analysis, differential calorimetry. phenolic content analyses performed EIS-MS2 high-pressure liquid chromatography. results showed that freeze-drying pulverization...