A5066752125- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Heart rate and cardiovascular health
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- COVID-19 and Mental Health
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Sodium Intake and Health
- Regulation of Appetite and Obesity
- Polyomavirus and related diseases
- COVID-19 Clinical Research Studies
- Bone and Joint Diseases
- Vasculitis and related conditions
- Thermoregulation and physiological responses
- Aortic Disease and Treatment Approaches
- ECG Monitoring and Analysis
- Neurological and metabolic disorders
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Dialysis and Renal Disease Management
- Cardiovascular Disease and Adiposity
University of Milano-Bicocca
2019-2025
University of Milan
2022
Weatherford College
2022
Orano (United States)
2022
Zero to Three
2022
Azienda Ospedaliera San Gerardo
2018
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2014
According to some guidelines, white-coat hypertension (WCH) carries little or no increase of cardiovascular risk in the absence organ damage (OD), but data are available on this issue.Using population from PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni), we evaluated and total mortality over a median follow-up 29 years WCH (elevated office normal 24-hour home blood pressure [BP]) normotensive controls (normal in- out-of-office pressure) with echocardiographic left ventricular...
Previous studies focused on the relationships between Serum Uric Acid (SUA) and lipids have found an association mainly with triglycerides. Furthermore, previous adiposity indices been evaluation of Visceral Adiposity Index (VAI). The present study was aimed at providing within same population a systematic SUA, employing both classic cutoff for hyperuricemia newly one identified by Right Heart Health (URRAH) study. We analyzed data collected in 1892 subjects Pressioni Arteriose Monitorate E...
Left ventricular hypertrophy (LVH) is an independent predictor of cardiovascular events, and evidence has been obtained that increase a normal left mass (LVM) or new-onset LVH over time augments outcomes.We addressed this issue in sample general population at relatively low risk. We analyzed subjects with echocardiographic LVM enrolled the PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) study to follow assess prognostic impact change on incidence events (mean follow-up 18.5...
Background: The value of the association arterial stiffness with left ventricular concentric remodelling/left hypertrophy (LVH) assessed by echocardiography, for prediction masked hypertension defined office and ambulatory blood pressure monitoring (ABPM) in general population is largely undefined. We investigated this topic participants to Pressioni Monitorate E Loro Associazioni (PAMELA) study. Methods: study included 272 (153 normotensives 119 hypertension) who attended second third...
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In patients with end-stage renal disease (ESRD) undergoing haemodialysis, hypertension is of common detection and frequently inadequately controlled. Multiple pathophysiological mechanisms are involved in the development progression ESRD-related high blood pressure state, which has been implicated increased cardiovascular risk reported this hypertensive clinical phenotype. Renal sympathetic efferent afferent nerves play a relevant role elevated values ESRD, often leading to resistant...
Rationale: Granulomatosis with polyangiitis (GPA) is an antineutrophil cytoplasmatic antibodies (ANCA)-associated vasculitis affecting small- and medium-sized blood vessels, mostly involving lung kidney. Patient concerns: We report the case of a 33-year-old man that presented acute respiratory distress syndrome caused by alveolar hemorrhage. Diagnoses: Aggressive GPA presenting diffuse hemorrhage multiorgan involvement. Inteventions: Immunosuppressive therapy, plasma exchange, extracorporeal...
Results of recent clinical trials have shown that in heart failure (HF) rate (HR) values > 70 beats/minute are associated with an increased cardiovascular risk. No information is available on whether the sympathetic nervous system differently activated HF patients displaying resting HR above or below this cutoff.In 103 aged 62.7 ± 0.9 (mean SEM) years and 62 heathy controls similar age we evaluated muscle nerve traffic (MSNA, microneurography) venous plasma norepinephrine (NE, HPLC assay),...
Abstract BACKGROUND Evidence on the association of arterial stiffness and left ventricular (LV) concentric remodelling/LVH assessed by echocardiography, with abnormal blood pressure (BP) phenotypes, defined office ambulatory BP monitoring (ABPM) in community is scanty. Thus, we investigated this issue participants to Pressioni Monitorate E Loro Associazioni (PAMELA) study. METHODS The present study included 491 who attended second third survey PAMELA performed after 10 25 years from initial...
Vitamin B12 deficiency-induced thrombotic microangiopathy, known as pseudothrombotic is a rare condition which resembles the clinical features of thrombocytopenic purpura but requires markedly different treatment. Most cases vitamin deficiency have only mild hematological findings, in approximately 10% patients life-threatening conditions been reported.We report case 46-year-old Moroccan man presenting with severe hemolytic anemia, thrombocytopenia, and renal failure absence macrocytosis,...
Scarce and non-homogeneous data are available on the prognostic value of clinic heart rate (HR) in coronavirus disease 2019 (COVID-19).The present study evaluated 389 patients hospitalized for COVID-19 in-hospital resting HR, assessed over different time periods, i.e., at hospital admission, during initial 3 days 7 hospitalization.Results show that assessment this hemodynamic variable hospitalization provides information clinical outcome patients, greater HR values being associated with a...
We examined whether to what extent resting heart rate (HR) values are capable reflect in the metabolic syndrome (MS) a different degree of sympathetic activation. also thought determine at which HR cutoff nervous system becomes more activated MS.In 70 MS patients aged 55.5 ± 1.8 (mean SEM) years we evaluated muscle nerve traffic (MSNA, microneurography) and venous plasma norepinephrine (NE, HPLC assay), subdividing study population three subgroups according clinic 24-h (< 70, 70-79 ≥ 80...
We assessed the value of 3 electrocardiographic (EKG) voltage criteria in detecting variations left ventricular mass (LVM) over time, taking echocardiographic (ECHO) LVM as reference, Pressioni Arteriose Monitorate E Loro Associazioni study. In 927 subjects (age 47 ± 13 years on entry, 49.9% men) an ECHO evaluation and EKG suitable for measurement EKG-LVH (Sokolow-Lyon voltage, Cornell R-wave aVL) were available at baseline a 2nd performed 10 later. Δ (delta) LVM, LVMI, parameters values...
Abstract Rationale: Whereas metronidazole-induced hepatotoxicity is quite rare in the general population, individuals carrying a nucleotide excision repair disorder, namely Cockayne syndrome, there high risk of developing this complication. Patient concerns: We report case 44-year-old man, affected by xeroderma pigmentosum, who was admitted to hospital presenting aspiration pneumoniae caused worsening dysphagia and with severe during hospitalization. Diagnoses: Acute hepatitis, which leading...
According to some guidelines white-coat hypertension (WCH) carries little or no increase of cardiovascular (CV) risk in absence organ damage (OD) but data are available on this issue.Using the population from Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA), we evaluated CV and total mortality over a median follow-up 29 years WCH (elevated office normal 24-hour home blood pressure, BP) normotensive controls (N, in- out-of-office with echocardiographic left ventricular hypertrophy...
We evaluated the relationships between Berlin questionnaire (BQ) scores, hypertension and other metabolic variables in 598 subjects (age: 65.8 ± 10 years, mean SD) enrolled PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) study representative of general population, treated or untreated with antihypertensive drugs. Two hundred eleven (35%) had a positive BQ two more categories inquiry. Compared to those without sleep disorders these showed greater male prevalence (55.9%), worse...
We examined in 11 young subjects (age 29.7±3.6 years, mean±SEM) whether carotid baroreceptor stimulation via the neck chamber device may affect central venous pressure (CVP), thus potentially involving other reflexogenic areas responses. Application of progressively greater subatmospheric pressures caused a progressive lengthening RR interval, which reached peak at maximal value negative applied. This was accompanied by significant and reduction CVP values when data were calculated...