Pamela Mda
A5027143210- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Emergency and Acute Care Studies
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Vaccine Coverage and Hesitancy
- HIV/AIDS Impact and Responses
- SARS-CoV-2 and COVID-19 Research
- Migration, Health and Trauma
- Hepatitis B Virus Studies
- vaccines and immunoinformatics approaches
- HIV/AIDS oral health manifestations
- Viral Infections and Immunology Research
- Trauma and Emergency Care Studies
- Poverty, Education, and Child Welfare
- Tuberculosis Research and Epidemiology
- Suicide and Self-Harm Studies
- COVID-19 Impact on Reproduction
- Immune responses and vaccinations
- Sepsis Diagnosis and Treatment
- Homelessness and Social Issues
Nelson Mandela Academic Hospital
2019-2025
Walter Sisulu University
2018-2021
Mthatha General Hospital
2013
A safe, effective vaccine is essential to eradicating human immunodeficiency virus (HIV) infection. canarypox–protein HIV regimen (ALVAC-HIV plus AIDSVAX B/E) showed modest efficacy in reducing infection Thailand. An analogous using HIV-1 subtype C potent humoral and cellular responses a phase 1–2a trial South Africa. Efficacy data additional safety were needed for this larger population
HIV type 1 (HIV-1) remains a global health concern, with the greatest burden in sub-Saharan Africa. Despite 40 years of research, no vaccine candidate has shown durable and protective efficacy against HIV-1 acquisition. Although pre-exposure prophylaxis groups high vulnerability can be very effective, barriers to its use, such as perceived low acquisition risk, fear stigma, concerns about side-effects, remain. Thus, population-based approach, an vaccine, is needed. The current study aimed...
The Eastern Cape province of South Africa has one the highest burdens HIV in world. Emergency Departments (EDs) can serve as optimal clinical sites for identification new infections and entry into care. We sought to determine current burden disease among ED patients Cape. conducted a prospective cross-sectional observational study EDs three Hospitals from June 2017 July 2018. All adult, non-critical presenting were systematically approached offered Point-Of-Care (POC) test accordance with...
South Africa faces the highest burden of HIV infection globally. The National Strategic Plan on recommends provider-initiated counselling and testing (HCT) in all healthcare facilities. However, continues to overwhelm system. Emergency department (ED)-based HCT could address unmet needs.This study examines reasons for accepting or declining African EDs inform development implementation strategies.We conducted a prospective observational two rural EDs, from June September 2017. Patients...
Background: In South Africa the teenage fertility rate is high. About 42% of women have their sexual debut by 18 years age and 5% 15. These young are also at risk sexually transmitted infections (STIs) human immunodeficiency virus (HIV) infection. Despite widespread availability contraception, 18% active teenagers do not use any. Previous research on knowledge of, attitudes to practices contraception has focused older adolescents.Objectives: This study explored knowledge, about amongst 12–14...
Emergency medicine accounts for a large proportion of medical care in many low- and middle-income countries. A better understanding the burden disease will guide training resource allocation priorities, but lack electronic records standardised data collection systems makes it difficult to obtain this information.To draw attention proportionally trauma emergency centres (ECs) throughout Eastern Cape Province, South Africa (SA), hope influencing provider protocols accordingly.A secondary...
BackgroundEmergency Departments (EDs) can serve as clinical sites for identification of new HIV infections and their entry into care. We examined if HIV-positive patients who present to EDs in South Africa are able successfully link care.MethodsWe conducted a one-year longitudinal prospective cohort study four hospitals across the Eastern Cape, Africa, with participants followed between July 2016 2018. All adult, non-critical presenting ED were systematically approached, asked about status,...
Background. Despite the breadth of data supporting evidence-based practice for sepsis care in high-resource settings, there are relatively few to guide management low-resource particularly areas where HIV and tuberculosis (TB) prevalent. Furthermore, studies had broadened parameters include all patients with acute infectious illness or followed up after hospital discharge. Understanding epidemiology outcomes infections a local context is critical first step developing locally informed...
Background: The Eastern Cape province of South Africa has one the highest burdens HIV in world. Emergency Departments (EDs) can serve as optimal clinical sites for identification new infections and entry into care. We sought to determine current burden disease among ED patients Cape. Methods: conducted a prospective observational study EDs three Hospitals from June 2017 July 2018. All adult, non-critical presenting were systematically approached offered Point-Of-Care (POC) test accordance...
HIV is a worldwide health problem with continuing high rates of new infections in many parts the world. This lack progress decreasing overall incidence has sparked innovative testing strategies, including expansion into emergency department (ED) setting. Emergency departments have been shown to be high-yield venues United States and other developed world settings. The feasibility expanding public services ED limited-resource countries unclear.We performed cross-sectional assessment...
Background: Emergency department (ED)-based screening for substance use, suicide, and safety is commonly conducted in the United States. We sought to adopt this ED-based strategy South Africa determine potential unmet needs of population.Materials Methods: This prospective, observational study was at two sites Eastern Cape from June September 2017. Adult patients presenting ED with noncritical conditions were approached collect demographic data, respond questions, receive point-of-care human...
Background: Emergency Departments (EDs) can serve as clinical sites for identification of new HIV infections and their entry into care. We examined if HIV-positive patients who present to EDs in South Africa are able successfully link care.Methods: conducted a one-year longitudinal prospective cohort study four hospitals across the Eastern Cape, between July 2016 2018. All adult, non-critical presenting ED were systematically approached, asked about status, and, unknown, offered...