Tuğçe Yakut
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- Drug-Induced Adverse Reactions
- Systemic Sclerosis and Related Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dermatology and Skin Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Urticaria and Related Conditions
- Herpesvirus Infections and Treatments
- Eosinophilic Disorders and Syndromes
- Obstructive Sleep Apnea Research
- IL-33, ST2, and ILC Pathways
- Pediatric health and respiratory diseases
- Synthesis of β-Lactam Compounds
- Contact Dermatitis and Allergies
- Vascular Tumors and Angiosarcomas
- Inflammatory mediators and NSAID effects
- Respiratory Support and Mechanisms
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and Treatment of Venous Diseases
- Health, psychology, and well-being
- Pulmonary Hypertension Research and Treatments
- School Health and Nursing Education
- Voice and Speech Disorders
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2022-2025
Sağlık Bilimleri Üniversitesi
2020-2024
Koç University
2024
Diyarbakır Askeri Hastanesi
2023
Weatherford College
2023
Association for Language Learning
2023
ENT and Allergy
2023
Yedikule Teaching Hospital
2020
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
Objective The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess differences between obese and non-obese patients with asthma.
National data on asthma characteristics and the factors associated with uncontrolled seem to be necessary for every country. For this purpose, we developed Turkish Adult Asthma Registry patients aiming take a snapshot of our patients, thereby assigning unmet needs niche areas intervention.Case entries were performed between March 2018 2022. A web-based application was used record data. Study outcomes demographic features, disease characteristics, control levels, phenotypes.The registry...
To evaluate drug resıstant tuberculosis patients who developed hypersensitivity to antituberculosis drug.This was a retrospective study. The primary aim of the study is determine demographic and clinical characteristics develop in resistant patients. secondary examine treatment results. Demographic features, diagnostic indicator, signs developing reaction, reaction time, were evaluated.A total 25 included prevalence resistance 11.9%. Twelve (48%) cases women. Mean age (mean ± SD) 37.24 14.44...
IntroductionNon-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) accompanies severe asthma in about 15% of the patients and may adversely affect prognosis. Omalizumab mepolizumab are biologics used with asthma. The objective this study is to assess improvements, after these asthmatic stratifed by presence concomitant Non-erosive reflux effect omalizumab asthmatics N-ERD.Material & methodThe population three-center, retrospective, cross-sectional, observational...
In obese severe asthmatics, the degree of type 2 inflammation may vary according to their atopic status and past smoking history. this study, we aimed analyze clinical physiopathological features nonobese asthmatics treated with omalizumab or mepolizumab treatment. addition compare clinical, spirometric outcomes total peripheral eosinophilic count (TEC) changes after treatment these biologic agents in groups. retrospective, cross sectional 121 asthmatic (omalizumab = 88 33) for at least 16...
Abstract Purpose Pulmonary involvement is common in adults with scleroderma. The effect of concomitant obstructive sleep apnea (OSA) on risk for pulmonary hypertension scleroderma unknown. An enlarged main artery diameter (mPAD) derived from chest computer tomography (CT) a useful predictor hypertension. We addressed the OSA and mPAD Methods All participants underwent function testing, carbon monoxide diffusion capacity, CT, overnight recording home testing. diagnosis was based an...
(1) Background: Systemic sclerosis (SSc) is a rare systemic disease, which often affects the esophagus, leading to dilation and complications such as dysphagia reflux. Obstructive sleep apnea (OSA) chronic condition with recurrent episodes of upper airway collapsibility known impair quality life (QoL). The primary aim this study was investigate occurrence esophagus in patients SSc concomitant OSA and, further, address impact these conditions on QoL. (2) Methods: In cross-sectional cohort...
Approximately 1-third of patients with severe asthma are candidates for both omalizumab and mepolizumab treatment. We aimed to compare the clinical, spirometric inflammatory efficacy these 2 biologics in atopic eosinophilic "overlap" patients. In our 3-center retrospective cross-sectional observational study, data who received or at least 16 weeks treat were examined. Atopic (perennial allergen sensitivity total IgE level 30-1500 IU/mL) (blood eosinophil counts ≥150 cells/µL admission; ≥300...
Objective The older adult population in Turkey has increased by 22.6% the last 5 years, and characteristics of such patients with asthma remain uninvestigated. Therefore, we aimed to evaluate adults according sex control status provide an in-depth overview this Turkey.
<b>Objective:</b> Obstructive sleep apnoea (OSA) may contribute to pulmonary hypertension in patients with scleroderma (SSc). Main artery (mPA) diameter derived from chest computer tomography (CT) is a reliable predictor of hypertension. In the current study, we explored relationship between OSA indices and enlarged mPA SSc. <b>Material Methods:</b> Sixty-two consecutive SSc (58 female) were included. All underwent lung function test, carbonmonoxide diffusion capacity (DLCO), CT, overnight...
Effectiveness of mepolizumab in patients with severe eosinophilic asthma: In a real life studyIntroduction : We analyzed the effects treatment on symptoms, asthma attacks, pulmonary function test parameters peripheral blood eosinophil level, and percentage receiving as baseline, sixth twelfthmonth data. Materials Methods:The medical records diagnosed treated at our clinic were retrospectively reviewed for period between January 2018 December 2021.Demographic data patients, duration disease,...
<b>Introduction:</b> Many patients couldn't reach sufficient expiration time during spirometry testing, which reduces the FVC value relatively, and FEV1 / ratio appears to be incorrectly high. We aimed determine prediction point for in with insufficient expiratory maneuver based on bronchoprovocation tests (BPT). <b>Methods:</b> In our retrospective cross-sectional study, pd20 values, FET plateau presence volume-time curve, FIVC - value, were recorded BPT suspended between 2018-2019....
Eczema herpeticum (EH), also known as Kaposi's varicelliform eruption, is a herpes simplex virus infection that develops mainly on the basis of pre-existing chronic dermatoses such atomic dermatitis, ichthyosis, seborrheic Darier's disease, pemphigus foliaceus, mycosis fungoides, psoriasis.Its association with atopic dermatitis has been reported most frequently.In this article, an 18-year-old female patient who was diagnosed eczema after subcutaneous allergen immunotherapy for allergic...