A5076452942- Lung Cancer Treatments and Mutations
- MRI in cancer diagnosis
- Molecular Biology Techniques and Applications
- Nutrition and Health in Aging
- Atrial Fibrillation Management and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Reproductive Biology and Fertility
- Genomics, phytochemicals, and oxidative stress
- Inflammatory mediators and NSAID effects
- COVID-19 Clinical Research Studies
- Salivary Gland Disorders and Functions
- Hemispheric Asymmetry in Neuroscience
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Physical Education and Pedagogy
- Music Therapy and Health
- Cancer, Hypoxia, and Metabolism
- Lymphatic System and Diseases
- Advanced Fluorescence Microscopy Techniques
- Heat shock proteins research
- Cell Image Analysis Techniques
- Sport Psychology and Performance
- Medical Imaging Techniques and Applications
- Paraoxonase enzyme and polymorphisms
- Natural Products and Biological Research
- Advanced MRI Techniques and Applications
Erzincan University
2022-2025
Ankara University
2018-2024
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
<title>Abstract</title> <bold>Background:</bold> We aimed to examine whether serum magnesium level is related cardiovascular events in hemodialysis patients by investigating the relationship between (Mg) and carotid intima media thickness (CIMT). <bold>Methods:</bold> In this cross-sectional study, we evaluated 88 patients. The mean CIMT of these was measured recorded doppler ultrasonography. Patients were divided into two groups according their level. Correlation analysis linear regression...
Previous research indicates that different exercise modes might create effects on cognition and peripheral protein signals. This study aimed to compare the of long-term participation in an open closed-skill cognitive functions Brain-derived neurotrophic factor Cathepsin B levels. 18 fencers, swimmers, sedentary controls between 18–25 years old participated study. Participants performed visuospatial working memory, verbal fluency selective attention tasks. Blood samples were tested for using...
According to population-based studies, lung cancer is the prominent reason for cancer-related mortality worldwide in males and also rising females at an alarming rate. Sorafenib (SOR), which approved treatment of hepatocellular carcinoma renal cell carcinoma, a multitargeted protein kinase inhibitor. Additionally, SOR subject interest preclinical clinical trials cancer. This study was designed assess vivo possible effects sorafenib (SOR) diethylnitrosamine (DEN)-induced carcinogenesis...
Background The aim of the study is to assess effect chronic lung disease on mortality in patients hospitalized with diagnosis prevariant COVID-19 Pneumonia compared without disease. Research design and methods A cohort 1,549 admitted pandemic clinic a was analyzed. Group 1 2 were terms treatment they received, admission intensive care, follow-up parameters. Results patient group consisted 231 participants (14.91%) (Group 1). but had 1,318 (85.19%). cases found receive more oxygen therapy...
To investigate the diagnostic performance of multiparametric magnetic resonance imaging (mpMRI) in differentiating prostate cancer (PCa) from prostatitis foci.This retrospective analysis included 81 biopsy-proven lesions (44 and 37 PCa). Normalized T2-signal intensity (nT2SI) SI on diffusion-weighted (b=1000 2000 mm2/s), apparent diffusion coefficient (ADC) values, peak SI, at end dynamic curves, mean time, enhancement percentage, washout percentage obtained contrast-enhanced (DCEI) were...
Abstract Chemical fixation is one of the most critical steps to retaining cellular targets as naturally possible. Recent developments in microscopy allow sophisticated detection and measuring techniques with which spatio-temporal molecular alterations conceivable. Here, we document competence glyoxal (Gly), a less-toxic dialdehyde molecule, paraformaldehyde (PFA) side-by-side (with or without Triton-X 100 permealization) live- fixed-cell preparations including human stem cells, spermatozoa,...
It is known that the use of inhaled corticosteroids increases incidence pneumonia in patients followed up with diagnosis chronic asthma and obstructive pulmonary disease (COPD). This study aimed to investigate contribution steroid severity mortality cases COVID-19 pneumonia.
Background/aim: Studies are showing that pulmonary rehabilitation (PR) increases diaphragmatic excursion by decreasing hyperinflation in patients with chronic obstructive disease (COPD). However, there is a lack of knowledge about its effects on the diaphragm thickness (dt) and contractility. This study aims to evaluate dt contractility before after PR COPD. Materials methods: All subjects participated an out-patient 6 weeks 3 sessions per week prospectively. Dyspnea severity,...
Background & objective: Perioperative anxiety affects 25-80% of all surgical patients. It has a negative impact on postoperative recovery, potentially increasing morbidity and mortality. The anxiolytic effects music therapy are well recognized, but its cognitive implications unknown. We examined the 440 Hz 432 pre-operative functions in patients scheduled for surgery. Methodology: study took place operating room our hospital. Following ethical committee approval, was launched....
Background & Objective: Cognitive impairment is common in people with multiple sclerosis (MS). The Framingham Risk Score (FRS) an algorithm used to estimate the 10-year risk of developing cardiovascular disease (CVDr). This study aimed evaluate possible associations between FRS and cognitive MS. Methods: Demographic characteristics, laboratory parameters, clinical findings, vascular factors, Brief International Assessment for MS (BICAMS) test results, CVDr scores were recorded 110...
ÖzAmaç: Bu pilot çalışma, tenis oynamanın ve tenisçilerde el tercihinin bilişsel işlevler üzerindeki etkilerini araştırmayı amaçlamıştır
Cyclooxygenase 2 (COX-2) is responsible for the therapeutic effects of indomethacin, while inhibition COX-1 enzyme and oxidative stress are its gastro-toxic effects. It has been reported that pycnogenol increases expression COX-1, suppresses rate COX-2 stress. Our aim in this study to investigate antiinflammatory activities pycnogenol, their combination (PI) rats examine on stomach tissue. In study, anti-inflammatory activity was investigated carrageenan-induced inflammatory paw edema albino...
Sarcopenia is a progressive and generalized loss of muscle mass function. The aim this study was to evaluate the frequency sarcopenia among patients with primary Sjögren's syndrome (SS) factors related sarcopenia.Forty-four female SS 44 control subjects were included in cross-sectional between February August 2019. evaluated by handgrip test, Skeletal Muscle Mass Index, gait speed test.Eleven (25.0%) had presarcopenia group 2 (4.5%) (p = 0.007). Compared subjects, lower results hand grip...
GİRİŞ ve AMAÇ: Atriyal fibrilasyon (AF),
Abstract Background: This study was designed to assess the possible beneficial effects of sorafenib (SOR) in diethylnitrosamine (DEN) induced lung carcinogenesis male rats and also examine its probable mechanisms action. Methods results: A total 30 adult were divided into three groups as (1) control, (2) DEN, (3) DEN+SOR. The chemical induction performed by injection DEN intraperitoneally at 150 mg/kg once a week for two weeks. DEN-administered co-treated with SOR 10 oral gavage 42 alternate...
Metastases and primary malignancies are common in the liver. Local ablative applications such as transarterial chemoembolization (TACE), radioembolization (TARE) provide minimally invasive safe treatment unresectable liver tumors. Early detection of response to prevents unnecessary toxicity cost non-responder patients provides an earlier use other options that may be effective. This study aimed identify role 18F-fluorothymidine (FLT) positron emission tomography/computed tomography (PET/CT)...
Purpose: Diabetic retinopathy (DR) is a frequent complication of DM (Diabetes Mellitus) and leading cause visual impairments. Serum paraoxonase 1 (PON1) an antioxidant enzyme that has antiatherogenic properties plays role in inhibiting the oxidation low-density lipoprotein (LDL). We investigate levels serum PON1 activity low-grade inflammatory markers patients with proliferative DR (PDR) or nonproliferative (NPDR); without diabetic macular edema (DME). Methods: evaluated 91 40 controls....