- Retinal Imaging and Analysis
- Asthma and respiratory diseases
- Medical Imaging Techniques and Applications
- Urticaria and Related Conditions
- Families in Therapy and Culture
- Digital Imaging for Blood Diseases
- Glaucoma and retinal disorders
- Advanced MRI Techniques and Applications
- Ottoman and Turkish Studies
- Islamic Thought and Society Studies
- Allergic Rhinitis and Sensitization
- Medical Image Segmentation Techniques
- Retinal Diseases and Treatments
- Advanced Vision and Imaging
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pediatric health and respiratory diseases
- Colorectal Cancer Treatments and Studies
- AI in cancer detection
- Blood groups and transfusion
- Food Allergy and Anaphylaxis Research
- Advanced X-ray and CT Imaging
- Drug-Induced Adverse Reactions
- Cell Image Analysis Techniques
- Underwater Vehicles and Communication Systems
- Turkish Literature and Culture
Sağlık Bilimleri Üniversitesi
2023-2025
Ministry of Health
2023-2025
Istanbul University
2020-2025
University of Health Sciences
2023
Education Training And Research
2023
University of Health Science
2023
GE Global Research (United States)
2007-2020
Ümraniye Eğitim ve Araştırma Hastanesi
2020
Turkcell (Turkey)
2020
Ankara Sosyal Bilimler Üniversitesi
2017
Algorithms are presented for rapid, automatic, robust, adaptive, and accurate tracing of retinal vasculature analysis intersections crossovers. This method improves upon prior work in several ways: automatic adaptation from frame to without manual initialization/adjustment, with few tunable parameters; robust operation on image sequences exhibiting natural variability, poor varying imaging conditions, including over/under-exposure, low contrast, artifacts such as glare; does not require the...
This paper describes a robust hierarchical algorithm for fully-automatic registration of pair images the curved human retina photographed by fundus microscope. Accurate is essential mosaic synthesis, change detection, and design computer-aided instrumentation. Central to 12-parameter interimage transformation derived modeling as rigid quadratic surface with unknown parameters. The parameters are estimated matching vascular landmarks recursively tracing blood vessel structure. parameter...
A fully automated approach is presented for robust detection and classification of changes in longitudinal time-series color retinal fundus images diabetic retinopathy. The method to: 1) spatial variations illumination resulting from instrument limitations both within, between patient visits; 2) imaging artifacts such as dust particles; 3) outliers the training data; 4) segmentation alignment errors. Robustness to variation achieved by a novel iterative algorithm estimate reflectance retina...
A number of marine biological, geological, and archaeological applications share the need for high‐resolution optical acoustic imaging sea floor [Ballard et al., 2002; Greene 2000; Shank 2002]. In particular,there is a compelling to conduct studies in depths beyond those considered reasonable divers (∼50 m) down at shelf edge continental slope (∼1000–2000 m). Some constraints associated with such work include requirement off small coastal vessels or fishing boats opportunity,and vehicle...
An algorithm for constructing image mosaics from multiple, uncalibrated, weak-perspective views of the human retina is presented and analyzed. It builds on an registering pairs retinal images using a noninvertible, 12-parameter, quadratic transformation model hierarchical, robust estimation. The major innovation linear, feature-based, noniterative method jointly estimating consistent transformations all onto mosaic "anchor image." Constraints this estimation are derived pairwise registration...
Large area mapping at high resolution underwater continues to be constrained by sensor-level environmental constraints and the mismatch between available navigation sensor accuracy. In this paper, advances are presented that exploit aspects of sensing modality, consistency redundancy within local measurements build high-resolution optical acoustic maps a consistent representation environment. This work is in context real-world data acquired using autonomous vehicles (AUVs) remotely operated...
Epithelial organ morphogenesis involves reciprocal interactions between epithelial and mesenchymal cell types to balance progenitor retention expansion with differentiation for evolution of tissue architecture. Underlying submandibular salivary gland branching is the regulated proliferation perhaps several populations, which have not been characterized throughout development, yet are critical understanding regeneration, disease. Here we applied a serial multiplexed fluorescent...
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
Hypersensitivity reactions (HSRs) to colecalciferol (vitamin D) have been rarely reported and the mechanism is unknown. As an alternative treatment was not recommended for vitamin D deficiency, a desensitization protocol with can be performed. We found that there no standard D. In this study, we aimed investigate clinical features skin test results of patients HSRs effectiveness 6-step in which applied oral drops colecalciferol. This retrospective cross-sectional study included 18 history...
Objective The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess differences between obese and non-obese patients with asthma.
Although laser retinal surgery is the best available treatment for choroidal neovascularization, current procedure has a low success rate (50%). Challenges, such as motion-compensated beam steering, ensuring complete coverage and minimizing incidental photodamage, can be overcome with improved instrumentation. This paper presents core image processing algorithms (1) rapid identification of branching crossover points vasculature; (2) automatic montaging video angiograms; (3) real-time...
Algorithms are presented for integrated analysis of both vascular and nonvascular changes observed in longitudinal time-series color retinal fundus images, extending our prior work. A Bayesian model selection algorithm that combines change information, image understanding systems outputs a novel manner is used to analyze such as increase/decrease width, disappearance/appearance vessels, well appearance/disappearance different kinds lesions. The overall system robust false due inter-image...
Abstract Purpose: The association hepatocyte growth factor receptor (Met) tyrosine kinase with prognosis and survival in colon cancer is unclear, due part to the limitation of detection methods used. In particular, conventional chromagenic immunohistochemistry (IHC) has several limitations including inability separate compartmental measurements. Measurement membrane, cytoplasm, nuclear levels Met could offer a superior approach traditional IHC. Experimental Design: Fluorescent-based IHC for...
This paper describes computer vision algorithms to assist in retinal laser surgery, which is widely used treat leading blindness causing conditions but only has a 50% success rate, mostly due lack of spatial mapping and reckoning capabilities current instruments. The novel technique described here automatically constructs composite (mosaic) image the retina from sequence incomplete views. mosaic will be useful ophthalmologists for both diagnosis surgery. new goes beyond published methods...
National data on asthma characteristics and the factors associated with uncontrolled seem to be necessary for every country. For this purpose, we developed Turkish Adult Asthma Registry patients aiming take a snapshot of our patients, thereby assigning unmet needs niche areas intervention.Case entries were performed between March 2018 2022. A web-based application was used record data. Study outcomes demographic features, disease characteristics, control levels, phenotypes.The registry...
Background: Although sleep disturbance is known to be common in patients with chronic spontaneous urticaria (CSU), hormone levels the blood have never before been studied CSU. Objective: In this study, we aimed evaluate serum melatonin Methods: For patient group, 80 recently diagnosed CSU, and, for control 75 healthy controls (HC) were included. The study participants' measured by using enzyme-linked immunosorbent assay method. CSU disease activity was evaluated score-7 (UAS-7), and quality...
Hereditary angioedema (HAE) attacks can be provoked with psychological factors. The aim of this study was to assess the effects anxiety, depression and stress related COVID-19 pandemic on disease activity HAE patients during quarantine period (QP) return normal (RTNP).
Background: Allergy to dental materials in prostheses and implants that leads device dysfunction is a challenging problem. Objective: In this prospective study, we aimed investigate the diagnostic role impact of patch test (DPT) results on outcome proceeding procedures with collaboration our allergy clinic clinics. Methods: A total 382 adult patients oral or systemic signs symptoms due applied were included. DPT 31 items was administered. The clinical findings after restoration according...
In 2020, World Allergy Organization (WAO) updated their diagnostic criteria for anaphylaxis, which differed as a result from the National Institute of and Infectious Diseases/Food Anaphylaxis Network (NIAID/FAAN) were still used in 2021 update European Academy Clinical Immunology (EAACI) anaphylaxis guideline. Our aim was to evaluate compare both attempt identify factors affecting severity anaphylaxis.The medical records patients who evaluated with suspected at 3 centers Türkiye between 2014...