Cihan Örçen
A5019710966- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mast cells and histamine
- Food Allergy and Anaphylaxis Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- IL-33, ST2, and ILC Pathways
- Sinusitis and nasal conditions
- Pediatric health and respiratory diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- PI3K/AKT/mTOR signaling in cancer
- Vaccine Coverage and Hesitancy
- Viral Infections and Immunology Research
- School Health and Nursing Education
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Health, psychology, and well-being
- Inflammatory mediators and NSAID effects
- Contact Dermatitis and Allergies
- Synthesis of β-Lactam Compounds
Kocaeli Üniversitesi
2021-2025
Sağlık Bilimleri Üniversitesi
2022-2025
University of Health Sciences Antigua
2024-2025
University of Health Science
2025
University of Health Sciences
2025
Istanbul Medeniyet University
2024
Weatherford College
2023
Association for Language Learning
2023
ENT and Allergy
2021-2023
İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2022
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
Objective The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess differences between obese and non-obese patients with asthma.
Considerable overlaps exist between asthma phenotypes and the clinical significance of these remains undetermined. The objective this study is to analyze characteristics overlap using data from Turkish Adult Asthma Registry (TAAR). This cross-sectional registry included 2053 adult patients (74.8% female) with asthma. Overall, 39.3% (n = 697) had allergic-eosinophilic (AE), 26.0% 461) allergic-non-eosinophilic (ANE), 21.3% 377) non-allergic-eosinophilic (NAE), 13.4% 237)...
Abstract Objectives It is aimed to assess how physicians use chest imaging in asthma and the relationship between pathological findings related disease characteristics radiological of asthmatic patients. Background The daily practice its contribution management are not well defined. common investigate pathologies that cause respiratory symptoms evaluate differential diagnoses In this study, as a subanalysis Turkish Adult Asthma Registry, outcomes patients were examined. Methods Between March...
Background and Objectives: Real-life data on the efficacy of biologic agents (BAs) asthma-comorbid CRSwNP are needed. Our primary goal is to investigate effects BAs symptoms, as well endoscopic tomography scores. secondary show a reduction in frequency acute sinusitis exacerbations need for surgery. Materials Methods: We conducted multicenter, retrospective, real-life study. screened patients with treated omalizumab or mepolizumab. A total 69 (40 F/29 M; n = 55, mepolizumab 14) were...
National data on asthma characteristics and the factors associated with uncontrolled seem to be necessary for every country. For this purpose, we developed Turkish Adult Asthma Registry patients aiming take a snapshot of our patients, thereby assigning unmet needs niche areas intervention.Case entries were performed between March 2018 2022. A web-based application was used record data. Study outcomes demographic features, disease characteristics, control levels, phenotypes.The registry...
To evaluate drug resıstant tuberculosis patients who developed hypersensitivity to antituberculosis drug.This was a retrospective study. The primary aim of the study is determine demographic and clinical characteristics develop in resistant patients. secondary examine treatment results. Demographic features, diagnostic indicator, signs developing reaction, reaction time, were evaluated.A total 25 included prevalence resistance 11.9%. Twelve (48%) cases women. Mean age (mean ± SD) 37.24 14.44...
Th2/Th1 mix pathological pathway may be seen as a common set of low eosinophilic phenotype in severe allergic asthma. This affect omalizumab treatment response. In our study, we aimed to investigate whether eosinophil count (EOS) and percentage (EOS%), lymphocyte ratio (ELR) neutrophil (NLR) predict treatment.Patients who received at least for one year allergy clinic were screened retrospectively. Baseline hemogram parameters, pre- post-treatment emergency admissions, annual attacks...
IntroductionNon-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) accompanies severe asthma in about 15% of the patients and may adversely affect prognosis. Omalizumab mepolizumab are biologics used with asthma. The objective this study is to assess improvements, after these asthmatic stratifed by presence concomitant Non-erosive reflux effect omalizumab asthmatics N-ERD.Material & methodThe population three-center, retrospective, cross-sectional, observational...
Approximately 1-third of patients with severe asthma are candidates for both omalizumab and mepolizumab treatment. We aimed to compare the clinical, spirometric inflammatory efficacy these 2 biologics in atopic eosinophilic "overlap" patients. In our 3-center retrospective cross-sectional observational study, data who received or at least 16 weeks treat were examined. Atopic (perennial allergen sensitivity total IgE level 30-1500 IU/mL) (blood eosinophil counts ≥150 cells/µL admission; ≥300...
In obese severe asthmatics, the degree of type 2 inflammation may vary according to their atopic status and past smoking history. this study, we aimed analyze clinical physiopathological features nonobese asthmatics treated with omalizumab or mepolizumab treatment. addition compare clinical, spirometric outcomes total peripheral eosinophilic count (TEC) changes after treatment these biologic agents in groups. retrospective, cross sectional 121 asthmatic (omalizumab = 88 33) for at least 16...
Objective: Omalizumab treatment has shown promise in managing Chronic spontaneous urticaria (CSU). This study focuses on evaluating its effect improving the quality of life and reducing CSU activity severity patients different age groups. Materials Methods: Conducted at Derince Training Research Hospital, this observational involved 50 patients, categorized into adolescents (≤18years, n=15) adults (>18years, n=35). Data were collected through clinical demographic assessments, including...
Background/aim: Allergic rhinitis can be associated with bronchial hyperreactivity (BHR) and create an increased risk for allergic asthma development. We aimed to investigate the effects of subcutaneous immunotherapy (SCIT) on BHR development in adult patients rhinitis. Material methods: The retrospective case-control study was carried out between November 2018 May 2019 Süreyyapaşa Chest Diseases Thoracic Surgery Training Research Hospital. In this study, data recorded a mite and/or...
Objective The older adult population in Turkey has increased by 22.6% the last 5 years, and characteristics of such patients with asthma remain uninvestigated. Therefore, we aimed to evaluate adults according sex control status provide an in-depth overview this Turkey.
Aim: Abdominal obesity (AO) can affect some disease developments such as diabetes, cardiovascular diseases, or thyroid autoimmunity.To date, there is no data on the anthropometric parameters' impact development of refractory chronic spontaneous urticaria (CSU).We evaluated AO course presence CSU and to determine possible associated risk factors for having CSU.Methods: This study was designed a retrospective collected from January 2021 April 2022.For determining AO, waist-to-height ratio...
Kounis sendromu alerji, hipersensitivite, anafilaksi veya anafilaktoid durumlar ile birlikte akut koroner sendromun eş zamanlı olarak meydana gelmesi tanımlanmaktadır.Patofizyolojide ana enflamatuar hücreler olan mast hücrelerinin degranulasyonuyla başta histamin olmak üzere çeşitli mediatörlerin salınımı rol almaktadır
Effectiveness of mepolizumab in patients with severe eosinophilic asthma: In a real life studyIntroduction : We analyzed the effects treatment on symptoms, asthma attacks, pulmonary function test parameters peripheral blood eosinophil level, and percentage receiving as baseline, sixth twelfthmonth data. Materials Methods:The medical records diagnosed treated at our clinic were retrospectively reviewed for period between January 2018 December 2021.Demographic data patients, duration disease,...