Hülya Dirol
- Asthma and respiratory diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- COVID-19 Clinical Research Studies
- Medical Imaging and Pathology Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tracheal and airway disorders
- Lung Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Sarcoidosis and Beryllium Toxicity Research
- Extracellular vesicles in disease
- Climate Change and Health Impacts
- SARS-CoV-2 and COVID-19 Research
- Vitamin D Research Studies
- Pneumothorax, Barotrauma, Emphysema
- Eosinophilic Disorders and Syndromes
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Respiratory and Cough-Related Research
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Inflammatory mediators and NSAID effects
- Dermatological and COVID-19 studies
- Synthesis of β-Lactam Compounds
- Parathyroid Disorders and Treatments
Akdeniz University
2018-2025
Akdeniz University Hospital
2020-2023
Chest Diseases Hospital
2022
Pamukkale University
2021
Antalya Bilim University
2021
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in management remain limited. This registry-based study evaluated use montelukast adult patients, examining demographic disease characteristics, control status, phenotypes, presence atopy, regimens. Among 2053 patients analyzed, 61.76% (n = 1268; mean age: 46.2 ± 14.3 years), predominantly females (~76%), received...
Abstract Background Asthma is one of the most common causes chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence asthma asthma‐related death. Objective In this study, we aimed to determine levels asthmatic patients according national database investigate effects social markers on disease control in our region. Methods This an analysis data from 2053 adult multicentre chart study Turkey. Socioeconomic (SES) were collected questionnaires form was...
Objective The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess differences between obese and non-obese patients with asthma.
National data on asthma characteristics and the factors associated with uncontrolled seem to be necessary for every country. For this purpose, we developed Turkish Adult Asthma Registry patients aiming take a snapshot of our patients, thereby assigning unmet needs niche areas intervention.Case entries were performed between March 2018 2022. A web-based application was used record data. Study outcomes demographic features, disease characteristics, control levels, phenotypes.The registry...
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal fibrotic lung disease. While recent studies have suggested the potential efficacy of tyrosine kinase inhibitors in managing IPF, masitinib, clinically used inhibitor, has not yet been investigated for its diseases. In previous study on an vitro neurodegenerative model, we demonstrated synergistic antitoxic antioxidant effects masitinib combined with cromolyn sodium, FDA‐approved mast cell stabilizer. This aims to...
Introduction: Pneumomediastinum (PM) is a self-limiting disease with good prognosis. Mediastinitis rare but potentially fatal complication of PM. Identification risk factors for mediastinitis essential better management. Methods: This single-center, retrospective study conducted in university hospital. Adult patients PM between January 2016 and June 2020 were involved the study. The data about age, gender, symptoms, signs, treatment, development mediastinitis, hospital stay, mortality...
It has been suggested that Vitamin D Deficiency (VDD) worsens lung functions and COPD lowers vitamin levels, but this not proven yet.The study was carried out between January 2014 September 2015. All the patients with 25 (OH) D3 measurements were included in study. The < 40-year-old, or a smoking history of less than 10 package-year, asthma, bronchiectasis, pneumonia, tuberculosis, cancer, excluded from Medical records about age, gender, pulmonary function test, body mass index (BMI), annual...
Pulmonary large cell neuroendocrine carcinomas (LCNEC) are one of the rare malignant neoplasms lung. A standard management model for LCNEC has not yet been established and poor prognostic factors treatment modalities still uncertain.LCNEC fairly have a prognosis. Determination risk associated with survival can contribute to its management.In this retrospective study, we analyzed data 42 patients. We obtained about age, gender, smoking history, symptoms, tumor size, location, pathological...
Objective: To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during vaccination period nationwide in Turkey. Methods: COVID-19 patients followed pandemic services across Turkey between January 1, 2021, March 31, 2022 were investigated retrospectively. Nosocomial was defined as a patient neither diagnosed with nor suspected at hospital admission confirmed ≥5 days after admission. The primary outcome this study in-hospital mortality; demographic...
Objective The older adult population in Turkey has increased by 22.6% the last 5 years, and characteristics of such patients with asthma remain uninvestigated. Therefore, we aimed to evaluate adults according sex control status provide an in-depth overview this Turkey.
Pulmonary aspergilloma (PA) is a chronic lung infection. Lobectomy the recommended surgical modality. However, recent studies have suggested that wedge resection may be better than lobectomy.We compared short-term complications and mortality according to methods in pulmonary aspergilloma.In this study, we analyzed patients diagnosed with PA period 2015-2019 at tertiary hospital. We obtained data about age, gender, smoking history, symptoms, radiological findings, operation technique,...
Psöriasis, genellikle benign
Amyloidosis is characterized by extra-cellular deposition of an insoluble fibrillary protein, amyloid in organs and tissues. It classified as either primary or secondary based on the presence concomitant diseases, ranging from chronic infection inflammation to malignancy limited systemic extent organ invasion. The clinical radiological manifestations amyloidosis are varrious often nonspecific, making a diagnostic challenge. Here, we present asymptomatic local pulmonary case, diagnosed during...
Background: The aim of this study was to investigate the effect bronchiectasis operation on anxiety and depression. Methods: Between August 2014 March 2019, a total 167 patients with (107 males, 60 females; mean age: 43.5±13.9 years; range, 18 84 years) who received medical (n=70) surgical (n=97) treatment were retrospectively analyzed. Data including patients" characteristics, indication, type, localization obtained from electronic patient files. reached via phone calls evaluated whether...
Although many years have passed since the first speculation that Human chorionic gonadotropin (hCG) could be effective in obesity treatment, its efficacy this regard has yet to proven.Unfortunately, we still come encounter hCG misuse, complicated with pulmonary thromboembolism.A 54-yearold female patient no prior medical history presented outpatient clinic pleuritic chest pain, but other respiratory symptoms.Two months earlier, she had applied a nutrition center lose weight and been started...
Smooth muscle tumors of uncertain malignant potential, the borderline arising from smooth cells, usually grow slowly and do not fulfill diagnostic criteria leiomyosarcoma its variants, but may behave in a manner. A 15-year-old female patient with an endobronchial mass left main bronchus on thoracic computed tomography underwent thoracotomy tracheobronchoplasty wide safe margin. Histopathological evaluation revealed tumor potential. There were no complications related to operation during...
Background: We have been encountering pulmonary nodules more frequently due to increased lung cancer screening programs and tomography imaging for other reasons. Although various guidelines developed regarding nodules, uncertainty continues on the follow-up management of nodules. Aim study: To define patients risk factors nodule characteristics that differentiate malignant from benign nodules.Material Methods: Patients with detected between August 2014 January 2019 in a university hospital...
Yellow nail syndrome (YNS) is a rare characterized by yellow-thick nails, lymphedema, and recurrent respiratory symptoms. Respiratory symptoms occur due to asthma, bronchitis, bronchiectasis, pneumonia, sinusitis, pleural, pericardial effusion. Pleural effusion usually bilateral, exudative, lymphocyte-predominant. Although about half of patients have pleural effusion, it not component the triad. Two classical triad, symptoms, enough for diagnosis. About hundred cases been reported in...
Aim: EBUS TBNA is an important diagnostic procedure for the intrathoracic lymph nodes. 21 G, 22 G and 25 needles are used sampling. Better samples can be expected to taken via needle, as inner diameter of needle larger. However, results studies comparing controversial. Methods: The study population consists patients with performed (Group 1; n=40) whom 2; n=40). data were retrospectively analyzed. ROSE was all samples. Results: sensitivity, specificity accuracy 95%, 85%, 93%, respectively....