- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Aquaculture disease management and microbiota
- Cancer-related molecular mechanisms research
- Genetic and phenotypic traits in livestock
- Aquaculture Nutrition and Growth
- Microplastics and Plastic Pollution
- Genetic diversity and population structure
- MicroRNA in disease regulation
- Physiological and biochemical adaptations
- Ichthyology and Marine Biology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Recycling and Waste Management Techniques
- Plant Molecular Biology Research
- Nanoparticles: synthesis and applications
- Genetic Mapping and Diversity in Plants and Animals
- Animal Nutrition and Physiology
- Environmental Toxicology and Ecotoxicology
- Graphene and Nanomaterials Applications
- Plant nutrient uptake and metabolism
- Cultural Heritage Management and Preservation
- Water Resources and Sustainability
- Machine Learning in Bioinformatics
- Polysaccharides and Plant Cell Walls
- Transgenic Plants and Applications
Foshan University
2015-2025
Second Military Medical University
2025
Inner Mongolia Normal University
2021-2024
Zhejiang University
2008-2022
Beike Biotechnology (China)
2019-2022
Nanjing Institute of Vegetable Science
2022
Sichuan University
2018-2022
West China Hospital of Sichuan University
2018-2022
BGI Group (China)
2015-2021
Ministry of Agriculture and Rural Affairs
2018
An emerging cavefish model, the cyprinid genus Sinocyclocheilus, is endemic to massive southwestern karst area adjacent Qinghai-Tibetan Plateau of China. In order understand whether orogeny influenced evolution these species, and how genomes change under isolation, especially in subterranean habitats, we performed whole-genome sequencing comparative analyses three species this genus, S. grahami, rhinocerous anshuiensis. These are surface-dwelling, semi-cave-dwelling cave-restricted,...
Abstract The Asian arowana ( Scleropages formosus ), one of the world’s most expensive cultivated ornamental fishes, is an endangered species. It represents ancient lineage teleosts: Osteoglossomorpha. Here, we provide a high-quality chromosome-level reference genome female golden-variety using combination deep shotgun sequencing and high-resolution linkage mapping. In addition, have also generated two draft assemblies for red green varieties. Phylogenomic analysis supports sister group...
Largemouth bass is an important commercially farmed fish in China, but the rapid expansion of its breeding has resulted increased incidence diseases caused by bacteria, viruses and parasites. In this study, moribund largemouth containing ulcer foci on body surfaces indicated most likely pathogens were iridovirus rhabdovirus members was confirmed using a combination immunohistochemistry, cell culture, electron microscopy conserved gene sequence analysis. We identified that these had been...
Vibrio parahaemolyticus is a leading cause of foodborne infections in China and threat to human health worldwide. The main objective this study determine the prevalence characteristic V. isolates fish, oyster shrimp samples from South domestic consumer market. To accomplish this, we examined 504 seafood 11 provinces China. rates were 9.38, 30.36, 25.60%, respectively. In summer (33.33%), was more common than that detected winter (14.01%). addition, identified 98 strains. antimicrobial...
Nanoplastics (NPs) can be taken up by aquatic organism and profoundly impact the growth fitness of animals in ecosystem. Currently, influence NPs commercial fish is still poorly documented, especially carnivorous freshwater fish. To investigate effects water on performance, oxidative stress, histopathology, intestinal microbiota Micropterus salmoides, juvenile (initial weight 14.56 ± 0.09 g) were exposed to 10 100 μg/L polystyrene (100 nm) for seven days nineteen days. The results showed...
This study measured the impact of alisol B 23‐acetate and A 24‐acetate, main active ingredients traditional Chinese medicine Alismatis rhizoma, on total cholesterol (TC), triglyceride (TG), high density lipoprotein‐cholesterol (HDL‐C), low (LDL‐C) levels hyperlipidemic mice. The binding 24‐acetate to key enzyme involved in metabolism TC, 3‐hydroxy‐3‐methylglutary‐coenzyme (HMG‐CoA) reductase, was studied using reagent kit method western blotting technique combined with a molecular simulation...
Mapping of quantitative trait loci (QTL) is essential for the discovery genetic structures that related to complex traits. In this study, we identified 264,072 raw SNPs (single-nucleotide polymorphisms) by double digest restriction site associated DNA sequencing (ddRADseq), and utilized 3029 these construct a linkage map in orange-spotted grouper (Epinephelus coioides) using regression mapping algorithm. The contained 24 groups (LGs) spanning total distance 1231.98 cM. Twenty-seven...
Abstract Purpose We used bioinformatics methods and Mendelian randomization (MR) analysis to investigate the hub genes involved in acute myeloid leukemia (AML) their causal relationship with hemolysis, explore a new direction for molecular biology research of AML. Methods first differentially analyzed peripheral blood samples from 62 healthy volunteers 65 patients AML Gene Expression Omnibus database obtain expressed (DEGs), intersected them sourced weighted gene co-expression network...
Transgene spreading is a major concern in cultivating genetically modified (GM) corn. Cross-pollination may cause the spread of transgenes from GM cornfields to conventional fields. Occasionally, seed lot contamination, volunteers, mixing during sowing, harvest, and trade can also lead transgene escape. Obviously, new biological confinement technologies are highly desired mitigate addition physical separation isolation methods. In this study, we report development built-in containment method...
All living organisms synchronize biological functions with environmental changes; melatonin plays a vital role in regulating daily and seasonal variations. Due to rhythmic activity of the timezyme aralkylamine N-acetyltransferase (AANAT), blood level increases at night decreases during daytime. Whereas other vertebrates have single form AANAT, bony fishes possess various isoforms aanat genes, though reasons are still unclear. Here, we taken advantage multiple unpublished teleost sequences...
Long noncoding RNAs (lncRNAs) are non-protein-coding that involved in a variety of biological processes. The pig is an important farm animal and ideal biomedical model. In this study, we performed genome-wide scan for lncRNAs multiple tissue types from pigs. A total 118 million paired-end 90 nt clean reads were obtained via strand-specific RNA sequencing, 80.4% which aligned to the reference genome. We developed stringent bioinformatics pipeline identify 2,139 high-quality multiexonic...
The monophyly of flatfishes has not been supported in many molecular phylogenetic studies. Pleuronectoidei, which comprises all but one family flatfishes, is broadly supported. However, the Psettodoidei, comprising single Psettodidae, often found to be most closely related other carangimorphs based on substantial sequencing efforts and diversely analytical methods. In this study, we examined why particular result obtained.The mitogenomes five were determined. Select representative...
Abstract Background Chinese clearhead icefish, Protosalanx hyalocranius, is a representative icefish species with economic importance and special appearance. Due to its great value in China, the fish was introduced into Lake Dianchi several other lakes from Taihu half century ago. Similar theSinocyclocheilus cavefish, has certain cavefish-like traits, such as transparent body nearly scaleless skin. Here, we provide whole genome sequence of this surface-dwelling generated draft assembly,...