A5079543317- Herpesvirus Infections and Treatments
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Influenza Virus Research Studies
- interferon and immune responses
- Veterinary Oncology Research
- Viral gastroenteritis research and epidemiology
- Cytomegalovirus and herpesvirus research
- Infectious Encephalopathies and Encephalitis
- Rabies epidemiology and control
- Toxoplasma gondii Research Studies
- Bird parasitology and diseases
- Parasitic Infections and Diagnostics
- T-cell and Retrovirus Studies
- Infectious Diseases and Mycology
- Heavy Metal Exposure and Toxicity
- Pediatric Hepatobiliary Diseases and Treatments
- RNA regulation and disease
- Virology and Viral Diseases
- HIV Research and Treatment
- Insect and Pesticide Research
- Oral and Maxillofacial Pathology
- Microbial infections and disease research
- Bacterial Infections and Vaccines
- Mercury impact and mitigation studies
Iwate University
2016-2024
Kagoshima University
2020
Tokyo Zoological Park Society
2020
Gifu University
2016
Hokkaido University
2005-2014
Intranasally inoculated neurotropic influenza viruses in mice infect not only the respiratory tract but also central nervous system (CNS), mainly brain stem. 26 , 34 Previous studies suggested that route of invasion virus into CNS was via peripheral system, especially vagus nerve. To evaluate transvagal transmission virus, we intranasally unilaterally vagectomized with a virulent (strain 24a5b) and examined distribution viral protein genome by immunohistochemistry situ hybridization over...
Abdominal ultrasonography is one of the most common diagnostic imaging modalities used for dogs with suspected insulinoma; however, pancreatic masses are clearly identified in fewer than half affected and benign nodules can be difficult to differentiate from malignant ones. The purpose this prospective study was describe contrast‐enhanced (CEUS) characteristics confirmed insulinoma a group dogs. Inclusion criteria were as follows: (1) repeated hypoglycemia (blood glucose levels <60 mg/dl,...
During spring 1989, thirty-three whooper swans (Cygnus cygnus) died at Lake Miyajima in Hokkaido, Japan; 15 were examined. The birds diagnosed as having subacute lead poisoning due to ingestion of spent shot. main gross findings bile-stained liver, edematous or gelatinous bone marrow, lining with hyperkeratosis and pellets the gizzard, proventricular impaction. Histopathologically, there was lead-hemolytic jaundice hemosiderosis liver spleen, hypoplasia marrow increased numbers polychromatic...
A six-month-old shiba dog with a one-month history of progressive motor dysfunction showed clinical signs cerebellar disorder, including ataxia, dysmetria and intention tremor the head. Histopathological ultrastructural studies revealed distended neurons packed membranous cytoplasmic bodies throughout central nervous system. The activities lysosomal acid beta-galactosidase in its leucocytes liver were less than 2 per cent control levels, compound accumulated brain was identified as GM1...
Swine hemagglutinating encephalomyelitis virus (HEV) causes or vomiting and wasting disease in suckling piglets. Neurotoropism of the has been demonstrated previous vivo studies. In present study, we investigated infectivity propagation HEV comparison with those pseudorabies (PRV), another neurotropic virus, using dorsal root ganglia cells newborn mice containing nerve non-neuronal cells. infected but did not infect cells, whereas PRV both cell types. By cytoskeletal inhibitors, it was...
The present study was conducted to determine the clinical and clinico-pathologic characteristics of Shiba dogs with GM1 gangliosidosis, which is due an autosomal recessively inherited deficiency lysosomal acid β-galactosidase activity. Clinical clinico-pathological features were investigated in 10 homozygous gangliosidosis. age at onset 5 6 months manifested progressive neurologic signs including loss balance, intermittent lameness, ataxia, dysmetria intention tremor head. unable stand by a...
Neural involvement following infections of influenza viruses can be serious. The neural transport from the periphery to central nervous system has been indicated by using mouse models. However, no direct evidence for neuronal infection obtained in vitro and mechanisms transmission have not reported. In this study, transneural a neurotropic A virus was examined compartmentalized cultures neurons dorsal root ganglia, results were compared with those pseudorabies virus, well-established...
Fowl glioma-inducing virus (FGV), which belongs to subgroup A of avian leukosis (ALV), is tumorigenic in the nervous system. In a zoological garden Japan, approximately 40% chickens, including Japanese fowls, were infected with FGV. Because this plays role as major supplier fowl for other gardens, FGV infection suspected have spread among ornamental chickens. study, prevalence disease was examined total 129 chickens three gardens by nested polymerase chain reaction (PCR), reverse...
So-called fowl glioma is characterized by multiple nodular gliomatous growths associated with disseminated non-suppurative encephalitis. To investigate the possibility of induction lesions, chicks Japanese bantams (Gallus gallus domesticus) and specific pathogen free chickens (C/O strain White Leghorn) were intracerebrally inoculated a brain homogenate or culture supernatant from bantam affected glioma. All 16 (89%) in groups showed encephalitis, 18 (82%) five (28%) developed nodules...
Odontogenic cysts, which showed cystic radiolucency in the jaw bone by radiographic examination and computed tomography, were enucleated operation 3 dogs. One dog had a odontogenic keratocyst incisive of right maxilla another 2 cases revealed dentigerous cysts mandible. These cyst walls or transpired semiconductor laser. Afterwards, osteogenesis was confirmed at defective part extirpation all cases, no recurrence has been noted any cases. is disease should be treated surgical transpiration.
The complete nucleotide sequence of the avian leukosis virus causing so-called fowl glioma has been previously determined. Primers were designed for detection glioma-causal (FGV) based on 3′ untranslated region viral genome. provirus and RNA FGV specifically detected in various organs tissues, including feather pulp, from experimentally infected birds using nested polymerase chain reaction (PCR) reverse transcription PCR. prevalence was evaluated 131 Japanese fowls a zoological garden Japan...
Fowl glioma is characterized by multiple nodular growth of astrocytes, and fowl glioma-inducing virus belonging to avian leukosis has been isolated from Japanese bantam as a causal agent. Subcutaneous neoplasms the head neck have reported in layer chickens since 2003 Japan, concurred these affected layers. In present study, histopathology 240 layers, including 18 layers with subcutaneous 222 kept was performed clarify characteristics Microscopically, 103 showed non-suppurative encephalitis,...
Fowl glioma-inducing virus (FGV), which belongs to avian leukosis (ALV) subgroup A, induces fowl glioma. This disease is characterized by multiple nodular gliomatous growths of astrocytes and has been previously reported in Europe, South Africa, Australia, the United States Japan. FGV variants have spread ornamental Japanese fowl, including bantams (Gallus gallus domesticus), However, it unclear how where emerged whether related past glioma European countries. In this study, prevalence...
A 72-day-old, female, Golden Retriever dog showed anorexia, coughing, nasal discharge, diarrhea and hematochezia, died on the 15th clinical day. Pathological examination revealed dual infection with canine distemper virus (CDV) adenovirus (CAV). CAV inclusion bodies occurred only in liver, biliary respiratory system, whereas CDV inclusions were demonstrated visceral organs systematically. The associated multifocal hepatocellular necrosis edematous swelling of wall gall bladder, suggesting...
Nineteen lead-poisoned white-fronted geese ( Anser albifrons), including nine immature birds, were examined pathologically. Subacute lead poisoning due to ingestion of spent shots was diagnosed pathologically and confirmed by demonstrating high concentration in the liver. The liver ranged from 6.9 67.7 mg/kg wet weight. most suggestive gross lesions mottled bile-stained eight proventricular impaction and/or presence pellets gizzard. Histologic consisted Kupffer cell hemosiderosis, large bile...
We have previously isolated an avian leukosis virus (ALV) from a chicken affected with so-called fowl glioma. A resistance-inducing factor test indicated that the isolate was classified into subgroup A. The distribution and pathogenicity were investigated in C/O specific pathogen free chickens infected ovo this virus. Histologically, 11 of 12 (92%) birds had non-suppurative encephalitis three (25%) showed characteristic nodules glioma at 50 or 100 days age. Non-suppurative myocarditis matrix...
The present review summarizes the current information on lead poisoning of waterfowl with special attention to that occurred in Japan. reviewed items are concerning incidence toxic disease, source toxicity and ecological environmental factors, absorption other relevant, susceptibilty toxicosis, clinical signs, pathology, diagnosis involving interpretation chemical analysis. pathological lesions associated vary considerably depending upon degree present. show any conclusive should be based a...