- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Ocular Infections and Treatments
- Intraocular Surgery and Lenses
- Scoliosis diagnosis and treatment
- Dermatoglyphics and Human Traits
- Reliability and Agreement in Measurement
- Clinical Laboratory Practices and Quality Control
- Olfactory and Sensory Function Studies
- Peripheral Artery Disease Management
- Reconstructive Surgery and Microvascular Techniques
- Urologic and reproductive health conditions
- Sleep and Wakefulness Research
- Infrared Thermography in Medicine
- Optical Coherence Tomography Applications
- Medical and Biological Sciences
- Nasolacrimal Duct Obstruction Treatments
- Cerebral Venous Sinus Thrombosis
- Mediterranean and Iberian flora and fauna
- Congenital limb and hand anomalies
- Retinal and Optic Conditions
- Antiplatelet Therapy and Cardiovascular Diseases
Instituto de Olhos de Goiânia
2014-2024
Universidade Federal de São Paulo
2015-2024
Instituto Benjamin Constant
2018-2024
Hospital de São João
2012-2024
Universidade Federal do Estado do Rio de Janeiro
2024
Hospital Braga
2024
Wills Eye Hospital
2024
Huangshan University
2022
ORCID
2022
Universidade do Estado do Rio de Janeiro
2018
PURPOSE: To present the Tomographic and Biomechanical Index (TBI), which combines Scheimpflugbased corneal tomography biomechanics for enhancing ectasia detection. METHODS: Patients from different continents were retrospectively studied. The normal group included 1 eye randomly selected 480 patients with corneas keratoconus 204 keratoconus. There two groups: 72 ectatic eyes no surgery 94 very asymmetric (VAE-E group) fellow of these topography (VAE-NT group). Pentacam HR Corvis ST (Oculus...
To report a case of progressive corneal ectasia after LASIK with no detectable preoperative risk factors and to present three-dimensional tomographic biomechanical findings on the contralateral unoperated eye that would be considered low for thereby good candidate based Randleman Ectasia Risk Score System (ERSS).A report, literature review, description novel screening criteria Pentacam (Oculus Optikgeräte GmbH) tomography are presented as well Ocular Response Analyzer (ORA, Reichert...
To compare the incidence of laser in situ keratomileusis (LASIK)-associated dry eye and need for postoperative cyclosporine A treatment after flap creation with a femtosecond mechanical microkeratome.Cole Eye Institute, Cleveland, Ohio, USA.Eyes were randomized to an IntraLase (30 or 60 kHz) Hansatome microkeratome. No patient had signs, symptoms, preoperatively. Flap thickness was determined by intraoperative ultrasonic pachymetry. Slitlamp assessments cornea dry-eye evaluated...
To optimize artificial intelligence (AI) algorithms to integrate Scheimpflug-based corneal tomography and biomechanics enhance ectasia detection.Multicenter cross-sectional case-control retrospective study.A total of 3886 unoperated eyes from 3412 patients had Pentacam Corvis ST (Oculus Optikgeräte GmbH) examinations. The database included 1 eye randomly selected 1680 normal (N) 1181 "bilateral" keratoconus (KC) patients, along with 551 topography very asymmetric (VAE-NT), their 474 ectatic...
Background: Ectasia development occurs due to a chronic corneal biomechanical decompensation or weakness, resulting in stromal thinning and protrusion. This leads steepening, increase astigmatism, irregularity. In refractive surgery, the detection of mild forms ectasia pre-operatively is essential avoid post-operative progressive ectasia, which also depends on impact procedure cornea. Method: The advent 3D tomography proven as significant advancement further characterize shape beyond front...
Purpose: To review the role of corneal biomechanics for clinical evaluation patients with ectatic diseases. Methods: A total 1295 eyes were included analysis in this study. The normal healthy group (group N) one eye randomly selected from 736 corneas, keratoconus KC) 321 keratoconus. 113 nonoperated 125 very asymmetric ectasia VAE-E), whose fellow presented relatively topography VAE-NT), also included. parameters tomography and obtained using Pentacam HR Corvis ST (Oculus Optikgeräte GmbH,...
To report the first clinical experience with topical losartan for treating a case of severe corneal haze after complicated laser in situ keratomileusis (LASIK).A 36-year-old woman presented left eye femtosecond laser-assisted LASIK. The had flap dislocation and significant striae, which been re-lifted. Uncorrected distance visual acuity (UDVA) was 20/200 corrected 20/30 at presentation, 52 days procedure. A dense layer subepithelial opacity (haze) noted cornea. patient elected to start...
ABSTRACT Purpose To compare topometric (front surface curvature) and tomographic (3D corneal shape) indices for diagnosing keratoconus. Methods Pentacam data from one eye randomly selected of 200 normals (N) 177 keratoconus (KC) were analyzed. Tomographic tested. Receiver operating characteristic (ROC) curves calculated, along with pairwise comparisons. Results All tested variables had significant differences among N KC (Mann-Whitney, p < 0.001). Most accurate higher AUC than best ones...
Introduction: Keratoconus and ectatic corneal diseases represent a hot area of research. The need to enhance diagnosis in order recognize milder forms the disease identify inherent predisposition for ectasia progression has gained significant importance because refractive surgery also due development new treatment modalities treat diseases. This article discusses nomenclature related diagnostic tests used characterize keratoconus diseases, providing prospective discussion on latest...
Purpose: To prospectively review the importance of biomechanical assessment in screening, diagnosis, prognosis, individualized planning, and clinical follow-up for ectatic corneal diseases.Methods: We demonstrate two commercially available devices to assess biomechanics vivo, Ocular Response Analyzer (ORA, Reichester, NY, USA) Corvis ST (Oculus, Wetzlar, Germany). Novel have been demonstrated provide vivo measurements, including Brillouin optical microscopy OCT elastography. Conclusion: The...
To investigate corneal wound healing following ultraviolet-A (UVA)/riboflavin collagen cross-linking (CXL) in rabbit corneas.Thirty-six rabbits were enrolled the study. Animals divided into three treatment groups and corneas analyzed at 24 hours 4 weeks postoperatively. Thus, each group had 6 time point. Treatment were: 1) standard UVA+riboflavin CXL, 2) UVA alone, 3) riboflavin alone. One eye of served as an untreated control eye. TUNEL assay was performed to detect stromal cell apoptosis....
To evaluate and compare tomographic, clinical, biomechanical data of patients with unilateral keratoconus healthy controls.Observational, case-control study. Complete clinical eye examination was followed by topographic (ATLAS), tomographic (Pentacam), (Ocular Response Analyzer) evaluation. Cases were sex- age-matched individuals for controls.Four had keratoconus, eight served as controls. Central corneal thickness 508±16 μm in the group, 531±12.7 fellow 528.6±40.7 control group (P>.125, all...
Abstract The aim of this study was to evaluate whether OCT topography the Bowman's layer and artificial intelligence (AI) can result in better diagnosis forme fruste (FFKC) clinical keratoconus (KC). Normal (n = 221), FFKC 72) KC 116) corneas were included. Some patients had fellow eye (VAE‐NT) with normal 30). Scheimpflug scans cornea analyzed. curvature surface aberrations (ray tracing) anterior corneal [air‐epithelium (A‐E) interface OCT] epithelium‐Bowman's (E‐B) (in only) calculated....
The biostatistics has gained significant importance in recent years, being one of the mainstays current scientific research. It a series concepts and rules that must be understood to carry out or analyze an article. In this review we will discuss some main tools utilized works interest ophthalmology, its applications limitations. Biostatistics: fundamental practical