A5054490944- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Allergic Rhinitis and Sensitization
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Retinal Diseases and Treatments
- Olfactory and Sensory Function Studies
- Multiple Myeloma Research and Treatments
- Systemic Lupus Erythematosus Research
- Nasolacrimal Duct Obstruction Treatments
- Ergonomics and Musculoskeletal Disorders
- Contact Dermatitis and Allergies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Biomedical Research and Pathophysiology
- Lysosomal Storage Disorders Research
- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Cytomegalovirus and herpesvirus research
- Retinal and Macular Surgery
- Drug-Induced Ocular Toxicity
Osaka University
2016-2025
Institut Penyelidikan Veterinar
2024
Toho University
2012-2023
Japan Society for the Promotion of Science
2023
Menicon (Japan)
2022
Suzuki (Japan)
2022
The Ohio State University
2021
Humanitas University
2021
Ophthalmology Associates (United States)
2021
Beihang University
2021
purpose. To study the sequential postblink changes in ocular higher-order aberrations (HOAs) patients with dry eye. methods. A wavefront sensor was used to measure HOAs sequentially for 30 seconds 20 eyes of The were classified into two groups, or without superficial punctate keratopathy (SPK) central cornea. During measurement, subjects required blink every 10 seconds. aberration data analyzed 4-mm diameter coma-like, spherical-like, and total up sixth-order Zernike polynomials. Total HOAs,...
To evaluate the prevalence and risk factors of relationship between meibomian gland dysfunction (MGD) dry eye (DE) in Japan.A population-based cross-sectional study.Participants filled questionnaires regarding ocular symptoms, systemic diseases, lifestyle factors. Meibomian gland-related parameters tear film-related were evaluated. Risk for MGD DE analyzed by using univariate multivariate logistic regression. Age-specific was estimated a general additive model with degree-3 natural splines....
To optimize artificial intelligence (AI) algorithms to integrate Scheimpflug-based corneal tomography and biomechanics enhance ectasia detection.Multicenter cross-sectional case-control retrospective study.A total of 3886 unoperated eyes from 3412 patients had Pentacam Corvis ST (Oculus Optikgeräte GmbH) examinations. The database included 1 eye randomly selected 1680 normal (N) 1181 "bilateral" keratoconus (KC) patients, along with 551 topography very asymmetric (VAE-NT), their 474 ectatic...
To investigate the effect of non-invasive tear stability assessment with forced eye opening on lower meniscus.Twenty-three eyes 23 patients aqueous-deficient dry and normal subjects were enrolled. All underwent imaging a Keratograph 5M equipped modified film scanning function. Lower meniscus images captured, height (TMH) was measured an integrated ruler before after break-up time (NIKBUT) measurements in each subject. Subjects instructed to keep their open as long possible during NIKBUT...
purpose. To investigate sequential changes in the optical quality of normal eyes associated with blinking. methods. Ocular higher-order aberrations (HOAs) were measured sequentially by using a wavefront sensor for 30 seconds 20 subjects. During measurement, subjects forced to blink every 10 seconds. The obtained aberration data analyzed central 4-mm diameter coma-like, spherical-like, and total HOAs up sixth-order Zernike polynomials. results. serial blinking classified into four groups...
To evaluate ocular forward light scattering and corneal backward in patients with dry eye.Thirty-five eyes 35 eye 20 of healthy control subjects were enrolled. The classified into two groups according to whether superficial punctate keratopathy the central 6-mm zone (cSPK) was present or not. Ocular quantified a straylight meter. Corneal from anterior, middle, posterior parts assessed densitometry program using Scheimpflug imaging system.Both had significantly higher intraocular than group...
Purpose: To determine the effect of rebamipide ophthalmic suspension on optical quality in patients with dry eye short break-up time (BUT) tear film. Methods: Twenty-six eyes 16 BUT type were enrolled and treated 2% suspension. At baseline at 2 4 weeks after initiating treatment, serial corneal higher-order aberrations (HOAs), BUT, fluorescein staining, Schirmer test measured. Patients asked to complete questionnaires about changes eye–related ocular symptoms treatment. Results: Before...
To investigate the association between visual function and ocular surface regularity in dry eye.We enrolled 52 eyes of eye patients (34 with superficial punctate keratopathy [SPK] central corneal region [central SPK] 18 without SPK) 20 normal control subjects. All had a best-corrected distance acuity better than 20/20. We measured two indices contrast sensitivity under photopic conditions: letter sensitivity. The area log (AULCSF) was calculated from obtained data. Straylight quantified...
PURPOSE: To test the detection of subclinical corneal ectasia using integrated Scheimpflug tomography and biomechanical assessment in a Japanese population. METHODS: This prospective, case–control study included 23 patients with very asymmetric (VAE) 70 normal controls. Patients VAE had defined clinical one eye fellow topography (VAE-NT). Objective for confirming VAE-NT cases having 0% similarity severity derived from Placido-disk based topography. Scheimpflug-based were performed. The...
Purpose: To validate and evaluate the use of a new biomechanical index known as Corvis index–laser vision correction (CBI-LVC) method for separating stable post-LVC eyes from with ectasia. Setting: 10 clinics 9 countries. Design: Retrospective, multicenter, clinical study. Methods: The study was designed 2 purposes: to develop CBI-LVC, which combines dynamic corneal response (DCR) parameters provided by high-speed Scheimpflug camera (CorVis ST; OCULUS Optikgeräte GmbH) then its ability...
Purpose: To study the effects of suppression blinking on quality vision in borderline cases evaporative dry eye. Methods: Ocular higher-order aberrations (HOAs) were measured sequentially for 30 seconds 10 eyes with a short tear film breakup time (TBUT; 3.0 ± 0.6 seconds) without ocular surface staining or deficiency. During measurements, subjects suppressed to every seconds, which is more than double TBUT. The aberration data analyzed comalike and spherical-like total HOAs sixth-order...
Purpose.: To investigate the effects of viscosity and suspensibility eyedrops for dry eye by evaluating an eyedrop with one solutions or no solution (0.3% sodium hyaluronate ophthalmic solution, 3% diquafosol 2% rebamipide suspension) on ocular higher-order aberrations (HOAs) forward light scatter. Methods.: We evaluated HOAs scatter before 1, 5, 10 minutes after instillation three in 15 healthy subjects. Saline served as control. The were measured a 4-mm pupil using wavefront sensor....