A5003320020- Nanoplatforms for cancer theranostics
- Insect Resistance and Genetics
- Luminescence and Fluorescent Materials
- Crystallization and Solubility Studies
- Nanoparticles: synthesis and applications
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Radioactive element chemistry and processing
- Entomopathogenic Microorganisms in Pest Control
- Analytical chemistry methods development
- Chemical synthesis and alkaloids
- Photodynamic Therapy Research Studies
- Chromium effects and bioremediation
- Adsorption and biosorption for pollutant removal
- Mosquito-borne diseases and control
- Insect Pest Control Strategies
- Catalytic Cross-Coupling Reactions
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Advanced Nanomaterials in Catalysis
- Bone Tissue Engineering Materials
- Covalent Organic Framework Applications
- Probiotics and Fermented Foods
- Insect symbiosis and bacterial influences
- Antimicrobial Peptides and Activities
Fujian Agriculture and Forestry University
2016-2025
Binzhou Medical University
2024
Binzhou University
2024
Fujian Institute of Research on the Structure of Matter
2011-2023
University of Chinese Academy of Sciences
2022-2023
Ministry of Education
2017-2023
Chinese Academy of Sciences
2011-2021
ZheJiang Institute For Food and Drug Control
2018
Scripps Research Institute
2014-2016
University of Pittsburgh
2010-2013
Here we reported the antibacterial effect and related mechanism of three nano-Mg(OH)(2) slurries using Escherichia coli as model bacteria. X-ray diffraction (XRD), scanning electron microscopy (SEM) laser particle size analysis revealed that as-synthesized Mg(OH)(2)_(MgCl2), Mg(OH)(2)_(MgSO4) Mg(OH)(2)_(MgO) are all composed by nanoflakes with different sizes, their aggregates in water 5.5, 4.5, 1.2 μm, respectively. Bactericidal tests showed efficiency is conversely correlated Mg(OH)(2)...
Functionalization of hydrogen-bonded organic frameworks (HOFs) for specific applications has been a long-lasting challenge in HOF materials. Here, an efficient way to integrate functional species the structure through constructing anionic framework is presented. The obtained HOFs, taking PFC-33 (PFC = porous materials from FJIRSM,CAS) as example, porphyrin photosensitizer backbone and commercial biocide counterions structure. permanent channels electrostatic interaction between provide...
Exploration of effective ways to integrate various functional species into hydrogen-bonded organic frameworks (HOFs) is critically important for their applications but highly challenging. In this study, according the "bottle-around-ship" strategy, core-shell heterostructure upconversion nanoparticles (UCNPs) and HOFs was fabricated first time via a ligand-grafting stepwise method. The UCNPs "core" can effectively upconvert near-infrared (NIR) irradiation (980 nm) visible light (540 nm 653...
A Pd(II)-catalyzed, selective δ-C(sp3)–H and δ-C(sp2)–H arylation method for free primary aliphatic amines using NH2 as a native directing group has been developed. variety of with adjacent quaternary centers and/or alpha esters react diverse range aryl heteroaryl iodides to provide δ-aryl δ-heteroaryl amines.
In recent years, aggregation-induced emission photosensitizers (AIE-PSs) for antibacterial photodynamic therapy (aPDT) have received increasing attention because of their ability to increase reactive oxygen species (ROS) generation in the aggregation state. However, effect still has great room improvement. Herein, we propose that if rotation some bonds AIE-PSs is restricted, nonradiative decay could be further suppressed boost fluorescence and ROS, so as improve efficacy. Following this...
Abstract BACKGROUND Citrus canker caused by Xanthomonas citri subsp. (Xcc) is a devastating bacterial disease that reduces citrus yield and quality, posing serious threat to the industry. Several conventional chemicals have been used control canker. However, this approach often leads excessive use of chemical agents, can exacerbate environmental pollution promotes development resistant Xcc. Therefore, there significant interest in efficient environmentally friendly technologies RESULTS In...
The mechanism of the interaction between nano-Mg(OH)2 adsorbent and uranyl in water was studied. At trace levels, is adsorbed as a monolayer on nano-Mg(OH)2, occupied small proportion adsorption sites. As concentration crosses over threshold, continuous increase capacity takes place. It indicates that, by taking pre-adsorbed nucleation centers, additional crystallizes forms U-rich nanocrystals well-scattered surface nano-Mg(OH)2. A strategy inducing fast crystal growth to micrometer-sized...
A general synthetic approach to β-carboline-containing alkaloids was developed. Two consecutive palladium-mediated processes, a Sonagashira coupling and Larock indole annulation reaction, are central the method. The scope of investigated found be amenable for constructing variety biologically significant natural products also preparing substituted analogues optimization analysis their biological properties.
In the present study, we used CaCO3 nanoparticles (CCNPs) as carriers to assess physicochemical characteristics and antibacterial effect of gentamicin sulfate (GS)-loaded CCNPs (CGPs). The results indicated that had relatively regular chain-like structure, size crystallites was around 62.5 nm. FT-IR analysis GS could effectively load onto CCNPs. Meanwhile, dosage would affect drug loading entrapment efficiency GS. prolong release GS, complete from extended up 24 h. Additionally, obviously...
A new approach for the convenient synthesis of dibenzazepinones is reported. The key step formation seven-membered ring through palladium-catalyzed intramolecular arylation an anilide enolate. reactions were completed in 10 min at 100 °C with moderate to excellent yields. Aminodibenzazepinone 1, core structure γ-secretase inhibitor LY411575, can be prepared five steps from 2-bromophenylboronic acid and 2-iodoaniline 60% overall yield. reported here compares favorably presently available...
Some nanomaterials, such as Mg(OH)2 nanoflakes, are heavily used in pollutant adsorption and removal. Residues from these environmental remediations potential hazardous materials. Safety evaluations of materials needed for protection human health. Although nanotoxicity has been widely investigated recent years, research on the toxicity nanoparticle/pollutant adducts rather inadequate. Here, we report cellular perturbations cytotoxicity nano-Mg(OH)2/Cr(VI) a case study to elucidate how impact...
Engineering probiotics have emerged as a potential strategy for the treatment of metabolic diseases. However, due to exceptional complexity these disorders and intricate relationship between gut microbes, it is difficult achieve an ideal therapeutic effect in specific disorder using only single engineered strain. In this work, we proposed probiotic cocktail by engineering two cascade bacteria treat hyperlysinemia, inherited lysine with loss α-aminoadipate semialdehyde synthase (AASS) activity. A
The traditional Bacillus thuringiensis (Bt) formulations for field applications are not resistant to harsh environmental conditions. Hence, the active ingredients of Bt bioinsecticides could degrade quickly and has low anti-ultraviolet ability in field, which significantly limits its practical application. In present study, we developed an efficient stable delivery system Cry11Aa toxins. We coated proteins with Mg(OH)2 nanoparticles (MHNPs), then assessed effects MHNPs on bioactivity...