A5043216431- Functional Brain Connectivity Studies
- Traumatic Brain Injury Research
- Health, Environment, Cognitive Aging
- Posttraumatic Stress Disorder Research
- Mental Health Research Topics
- Anesthesia and Neurotoxicity Research
- Neural dynamics and brain function
- Traumatic Brain Injury and Neurovascular Disturbances
- Treatment of Major Depression
- Advanced MRI Techniques and Applications
- Neonatal and fetal brain pathology
- EEG and Brain-Computer Interfaces
- Electrochemical Analysis and Applications
- Memory and Neural Mechanisms
Neurosciences Institute
2018-2020
Stanford University
2017-2020
Mental Illness Research, Education and Clinical Centers
2018-2019
VA Palo Alto Health Care System
2018-2019
New York University
2019
A mechanistic understanding of the pathology psychiatric disorders has been hampered by extensive heterogeneity in biology, symptoms, and behavior within diagnostic categories that are defined subjectively. We investigated whether leveraging individual differences information-processing impairments patients with post-traumatic stress disorder (PTSD) could reveal phenotypes disorder. found a subgroup PTSD from two independent cohorts displayed both aberrant functional connectivity ventral...
Abstract Concurrent single‐pulse TMS‐EEG (spTMS‐EEG) is an emerging noninvasive tool for probing causal brain dynamics in humans. However, addition to the common artifacts standard EEG data, spTMS‐EEG data suffer from enormous stimulation‐induced artifacts, posing significant challenges extraction of neural information. Typically, signals are analyzed after a manual time‐intensive and often subjective process artifact rejection. Here we describe fully automated algorithm A key step this...
The authors sought to identify brain regions whose frequency-specific, orthogonalized resting-state EEG power envelope connectivity differs between combat veterans with posttraumatic stress disorder (PTSD) and healthy combat-exposed veterans, determine the behavioral correlates of connectomic differences.The first conducted a method validation study in control subjects (N=36). They then two-site case-control without PTSD who were deployed Iraq and/or Afghanistan. Healthy individuals (N=95)...
A major challenge in understanding and treating posttraumatic stress disorder (PTSD) is its clinical heterogeneity, which likely determined by various neurobiological perturbations. This heterogeneity also reduces the effectiveness of standard group comparison approaches. The authors tested whether a statistical approach aimed at identifying individual-level neuroimaging abnormalities that are more prevalent case subjects than control could reveal new clinically meaningful insights into...