- Child and Adolescent Psychosocial and Emotional Development
- Migration, Health and Trauma
- Eating Disorders and Behaviors
- Child Abuse and Trauma
- Posttraumatic Stress Disorder Research
- Functional Brain Connectivity Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Education and experiences of immigrants and refugees
- Transcranial Magnetic Stimulation Studies
- Attention Deficit Hyperactivity Disorder
- Child Nutrition and Feeding Issues
- Autism Spectrum Disorder Research
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Genetic Associations and Epidemiology
- Mental Health Research Topics
- Obesity, Physical Activity, Diet
- Obsessive-Compulsive Spectrum Disorders
- Personality Disorders and Psychopathology
- Regulation of Appetite and Obesity
- European Politics and Security
- Social and Demographic Issues in Germany
- Suicide and Self-Harm Studies
- Genetic Syndromes and Imprinting
- Identity, Memory, and Therapy
- Sexuality, Behavior, and Technology
VA Palo Alto Health Care System
2015-2020
Stanford University
2015-2020
Neurosciences Institute
2015-2020
Medical University of Vienna
2010-2020
Mental Illness Research, Education and Clinical Centers
2015-2019
Universitätsklinik für Kinder und Jugendpsychiatrie
2016-2018
Genomics (United Kingdom)
2017
University of Duisburg-Essen
2016
University of Vienna
2011-2016
American Academy of Child and Adolescent Psychiatry
2014
Insufficient default mode network (DMN) suppression was linked to increased rumination in symptomatic Major Depressive Disorder (MDD). Since is known predict relapse and a more severe course of MDD, we hypothesized that similar DMN alterations might also exist during full remission MDD (rMDD), condition be associated with rates specifically patients adolescent onset. Within cross-sectional functional magnetic resonance imaging study activation connectivity (FC) were investigated 120 adults...
A mechanistic understanding of the pathology psychiatric disorders has been hampered by extensive heterogeneity in biology, symptoms, and behavior within diagnostic categories that are defined subjectively. We investigated whether leveraging individual differences information-processing impairments patients with post-traumatic stress disorder (PTSD) could reveal phenotypes disorder. found a subgroup PTSD from two independent cohorts displayed both aberrant functional connectivity ventral...
BackgroundAlthough attention-deficit/hyperactivity disorder (ADHD) and eating disorders (EDs) frequently co-occur, little is known about the shared etiology. In this study, we comprehensively investigated genetic association between ADHD various EDs, including anorexia nervosa (AN) other EDs such as bulimia nervosa.MethodsWe applied different genetically informative designs to register-based information of a Swedish nationwide population (N = 3,550,118). We first examined familial...
Summary Background Alzheimer’s disease has chronic inflammatory components, which can be enhanced by systemic immune activation resulting in inflammation or vice versa . There is growing evidence that periodontitis drives and finally disease. Thus, a link might exist between oral pathogens This may of special significance as there an age-related incidence periodontitis. Methods In this study, 20 consecutive patients with probable were investigated. Diagnosis was established cognitive tests,...
Hippocampal volume loss has been related to chronic stress as well genetic factors. Although and environmental variables affecting hippocampal have extensively studied mental illness, limited evidence is available with respect G × E interactions on volume. The present MRI study investigated interaction effects between three well-studied functional variants (COMT Val158Met, BDNF Val66Met, 5-HTTLPR) associated a measure of adversity (life events questionnaire) in large sample healthy humans...
Abstract Due to lacking predictors of depression recovery, successful treatment major depressive disorder (MDD) is frequently only achieved after therapeutic optimization leading a prolonged suffering patients. This study aimed determine neural prognostic identifying non-remitters prior or early initiation. Moreover, it intended detect time-sensitive mediators indicating recovery. longitudinal, interventional, single-arm, open-label, phase IV, pharmacological functional magnetic resonance...
To examine the implications of an ontology aggressive behavior which divides aggression into reactive, affective, defensive, impulsive (RADI) or "emotionally hot"; and planned, instrumental, predatory (PIP) cold." Recent epidemiological, criminological, clinical neuroscience studies converge to support a connection between emotional trauma related psychopathology disturbances in emotions, self-regulation has important for diagnosis treatment, especially delinquent populations. Selective...
Prefrontal dopamine levels are relatively increased in adolescence compared to adulthood. Genetic variation of COMT (COMT Val158Met) results lower enzymatic activity and higher availability Met carriers. Given the dramatic changes synaptic during adolescence, it has been suggested that effects Val158Met genotypes might have oppositional adolescents adults. The present study aims identify such adults prefrontal brain networks at rest. Resting state functional connectivity data were collected...
There is limited research exploring attachment style and defenses in adolescents. The purpose of the current to explore relationship between adolescent development defense mechanisms, as well problem behaviors. A total 1487 students from two California high-schools completed three self-report questionnaires establish psychiatric symptoms, style. Attachment styles characterized by a positive self-image predict greater levels mature lower immature both interpersonal intrapsychic domains....
This study examines retrospective correlates of nonshared family environment prior to onset disease, by means multiple familial informants, among anorexia and bulimia nervosa patients.A total 332 participants was included (anorexia nervosa, restrictive type (AN-R): n = 41 plus families); bulimic patients binge-purging type; nervosa: 59 families). The EATAET Lifetime Diagnostic Interview used establish the diagnosis; Subjective Family Image Test derive emotional connectedness (EC) individual...